Mortality and morbidity due to cardiovascular disease are prevalent and costly for the 30 million patients who undergo noncardiac surgery annually in the United States, affecting more than 1 million of them.¹,² In the subgroup of 3 million patients who ...

Chronic neck pain after whiplash injury has defied diagnosis and treatment. The Quebec Task Force on Whiplash-Associated Disorders found almost no literature to substantiate the use of commonly practiced treatments for this condition.¹ In about half of ...

Stage II or Dukes' stage B2 colorectal cancer accounts for approximately one third of the cases of colorectal cancer diagnosed annually in the United States. Surgery can cure 80 percent of these cases, but the prognosis is poor in the remainder, and ...

Figure 1. A 52-year-old man with no history of serious illness presented with abdominal pain, dark-colored urine, light-colored stools, and jaundice. Abdominal ultrasonography revealed dilatation of the intrahepatic and extrahepatic bile ducts. Surgical ...

Recent research indicates that academic–industrial relationships in the life sciences have substantial benefits for industrial sponsors and that the rate of industrial support of academic life-science research may have increased over the past 10 years.¹ ...

Chorionic tumors, or gestational trophoblastic diseases, originate from placental tissues and are among the rare human tumors that can be cured even in the presence of widespread metastasis.¹–⁴ Gestational trophoblastic diseases include a spectrum of ...

Currently, there are 50,000 to 75,000 girls and women with Turner's syndrome in the United States alone. Turner's syndrome, first described in 1938,¹ is the most common sex-chromosome abnormality in females, affecting an estimated 3 percent of all females ...

Stage

A 73-year-old man came to the emergency room because of progressive weakness in his left leg. One year earlier, he had noted a sudden weakness in the left lower leg as he was climbing a flight of stairs. He did not seek medical attention at that ...

The cardiovascular assessment of patients undergoing noncardiac surgery has been intensively investigated over the past 10 years. These studies have culminated in guidelines recently published by a joint task force of the American College of Cardiology ...

Controlled studies of surgical and other invasive procedures to treat pain are few and far between. By their very nature, such procedures are not amenable to the study designs that have become standard in pharmacologic trials.¹ Many of the procedures ...

To the Editor: The proposal by Miller and Fins (June 27 issue)¹ that hospital care be restructured, with more explicit attention to dying patients, highlights an important and unmet need within our health care system. The quality of hospice care has been ...

To the Editor: Petitti et al. (July 4 issue)¹ reported a low risk of stroke among women using oral-contraceptive preparations low in estrogen, a result that agrees with the findings of our case–control study.² Their study shows an apparent protective ...

To the Editor: In their review of postherpetic neuralgia Drs. Kost and Straus (July 4 issue) ¹ suggest that narcotic analgesic drugs be given before antidepressant drugs (or carbamazepine) in patients with this disorder. The use of opioid narcotic drugs ...

To the Editor: In their study of treatment with co-trimoxazole (trimethoprim–sulfamethoxazole) to prevent relapses of Wegener's granulomatosis (July 4 issue),¹ Stegeman et al. do not report the cumulative doses of cyclophosphamide and prednisolone in ...

To the Editor: The α-tocopherol–transfer protein (α-TTP) is presumed to function in the intracellular transport of α-tocopherol, the most biologically active form of vitamin E. We described a patient with adult-onset Friedreich's ataxia in whom a ...

To the Editor: I have been a reader of the Journal for many years and learn a great deal from it. From the Brief Report on Mycobacterium ulcerans osteomyelitis by Hofer et al. (April 8, 1993, issue),¹ I learned for the first time about this new strain of ...

Epidemiology came of age during the last half of the 20th century as a fundamental scientific discipline for the advancement of our understanding of disease. From the association between cigarette smoking and lung cancer to the link between munitions ...

In this book . . .,” states Dr. Mayhall in the preface, “an attempt has been made to pull together all the information in this field under one cover.” This is indeed an ambitious goal, given that hospital epidemiology is related to microbiology, ...

The Art and Science of Cytopathology is a comprehensive textbook and atlas, with one volume on exfoliative cytology and another on fine-needle–aspiration cytology. It is extensively cross-referenced and provides a complete and up-to-date examination of ...

This multiauthored textbook and atlas on digestive tract surgery in adults is for the benefit of both future and practicing general surgeons. It contains substantial information about the diseases for which digestive tract surgery is intended, the ...

This book has 14 symptom-oriented chapters (on topics such as right-upper-quadrant pain, diarrhea, and trauma). Each chapter gives a brief discussion of the clinical presentation, followed by a review of relevant radiologic studies grouped according to ...

The Marlboro Man and Joe Camel have become public health enemies number one and two, and removing their familiar faces from the gaze of young people has become a goal of President Bill Clinton and his health care officials.¹ The strategy of limiting the ...

Recurrence of Autoimmune Diabetes Mellitus in Recipients of Cadaveric Pancreatic Grafts Original Article, N Engl J Med 1996:335;860-863.. On page 860, in the legend to Figure 1, the sentence that begins on line 5 should have read, “In Patient 1, serum C ...