Surfactant therapy has substantially improved the survival of premature infants with respiratory distress syndrome¹ but is not uniformly effective. Ventilation with perfluorocarbon liquids improves lung function in conditions involving surfactant ...

Although it is widely believed that pregnancy and the period shortly after pregnancy are associated with an increased risk of stroke, quantitative data supporting this assumption are scant.¹ Most of the studies of stroke and pregnancy have been based on a ...

In recent years, the common underlying pathophysiology of acute coronary syndromes involving the fissure or rupture of atherosclerotic plaques with mural or occlusive thrombus has been increasingly recognized.¹–⁴ Therapy for the various acute coronary ...

Polychlorinated biphenyls — synthetic hydrocarbon compounds once used as insulating materials in electrical transformers and capacitors — are among the most ubiquitous and persistent environmental contaminants.¹,² Although these lipophilic compounds have ...

Figure 1. A 14-year-old girl and her 6-year-old sister presented with pruritus in the postauricular area. Multiple small, white capsules were found firmly attached to their hair. Examination of the hair under a light microscope at a magnification of 100 ...

Studies of the use of services in the first two decades of the Medicare program showed that racial disparities were disappearing with regard to overall measures, such as rates of visits to physicians and hospital discharges.¹–³ In 1967, the first full ...

Malaria is the world's most important parasitic infection. Although it has been eradicated from temperate zones, increasing numbers of travelers from temperate areas each year visit tropical countries, where the disease remains a major cause of morbidity ...

Presentation of Case

A 45-year-old woman (gravida 3, para 0) was admitted to the hospital because of increasing lower abdominal pain.

Four weeks before admission, the patient had been seen at another hospital because of lower abdominal pain on urination. ...

These are exciting times in neonatology. During the past decade, treatment with exogenous surfactant has improved survival among infants with very low birth weight and respiratory distress syndrome, and new regimens of surfactant treatment and methods of ...

More than half a century has passed since the publication of Gunnar Myrdal's An American Dilemma, a monumental study that illuminated the profound disparity between this nation's democratic principles and egalitarian commitments and the realities of its ...

To the Editor: Stanley et al. (May 9 issue)¹ report that a booster dose of tetanus toxoid increases the expression of human immunodeficiency virus type 1 (HIV-1) in HIV-1–infected subjects. We have observed the effect of tetanus-toxoid boosters on five ...

To the Editor: The report by Miller et al. (May 16 issue)¹ on the development of a serologic test for Kaposi's sarcoma–associated herpeslike virus (KSHV) is an important initial step in determining the potential causative role of this new agent in Kaposi'...

To the Editor: In their review of coronary artery disease in women, Douglas and Ginsburg (May 16 issue)¹ define major, intermediate, and minor determinants of coronary artery disease. They define a high-risk group (with a pretest probability of disease ...

To the Editor: In the clinical discussion of Case 11-1996 (April 11 issue),¹ no mention was made of the possible role of anticoagulation in the patient's progressive illness. The patient had chronic renal insufficiency with marked proteinuria. Three ...

To the Editor: O'Dell et al. (May 16 issue)¹ addressed the important topic of optimal therapy for rheumatoid arthritis. However, we are concerned that the authors' conclusions — “in patients with rheumatoid arthritis, combination therapy with ...

To the Editor: From June 1992, when finasteride (Proscar) was approved for the treatment of prostatic hyperplasia, to February 1995, the Food and Drug Administration (FDA) received reports of gynecomastia in 214 men (ages, 47 to 90 years; median, 71) in ...

To the Editor: The anaerobic bacterium Clostridium botulinum produces the most potent food-related toxin known to humans.¹ Although the effects of botulinum toxin are well documented, little is known about the effects of the toxin on the developing ...

To the Editor: In their study of a national outbreak of Salmonella enteritidis infections associated with the consumption of ice cream (May 16 issue),¹ Hennessy and colleagues show how effective the appropriate use of epidemiologic tools can be. However, ...

Weight and size impressed me as I pulled the two volumes of Cutaneous Medicine and Surgery out of the box. The two books together weigh about 15 lb and take up nearly 5 in. of shelf space. Bound in a handsome black cloth cover with gold and red print, ...

Skin biopsies are as important to dermatologists as radiographs are to orthopedists and as electrocardiograms are to cardiologists. But students and primary care physicians are usually sheltered from dermatopathology. Many do not realize that training in ...

This book begins with dramatic color plates showing the different forms of skin involvement in systemic sclerosis (or scleroderma) and pictures of the histopathology of the disease. Also commendable is the opening chapter, an interesting and scholarly ...

Skin cancer is the number-one type of cancer in the United States, with over 1 million diagnoses expected in 1996. Management of this huge problem is complicated, because so many dermatologic conditions are dealt with by primary care physicians — only the ...