In the United States, Salmonella enteritidis has become the most commonly reported serotype of salmonella causing disease in humans.¹ A major factor in this change has been the consumption of undercooked eggs or egg products contaminated with S. ...

Rheumatoid arthritis is a common disease¹ that causes substantial morbidity in most patients² and premature mortality in many.²–⁴ Conventional therapy for rheumatoid arthritis includes the administration of antiinflammatory drugs, followed by disease-...

Kaposi's sarcoma, a multifocal vascular tumor, was first described by the Hungarian-born dermatologist Moritz Kaposi in 1872.¹ The classic form predominantly affects men of Eastern European and Mediterranean heritage.² Kaposi's sarcoma also occurs in ...

Recent guidelines from the Centers for Disease Control and Prevention (CDC)¹ assert that the majority of health benefits from physical activity can be achieved by walking 2 miles (3.2 km) briskly most days of the week (the energy equivalent of running 8 ...

Figure 1. The last case of smallpox within a 20-nation area of west and central Africa was found in Nigeria on May 21, 1970. This event marked the success of a five-year program to eradicate smallpox from a large area in which it was endemic. The 27-year-...

Many studies have documented racial and ethnic disparities in the U.S. health care system. Blacks and Hispanics have less access to health care, and the quality and outcomes of the care they receive are worse than those of non-Hispanic whites.¹–⁴ Little ...

The evaluation of chest pain is a critical step in the care of women with heart disease. It is a point at which women are likely to be treated differently from men,¹–⁶ especially when the diagnosis has not been established. Among patients known to have ...

Presentation of Case

A 79-year-old woman was admitted to the hospital because of anorexia, weight loss, dehydration, and diarrhea.

The patient had been well until six months earlier, when anorexia developed. Six weeks before admission, diarrhea began. ...

The microbiologic hazards of food present an issue of increasing concern.¹,² In the not-so-distant past, most food was produced and consumed locally. In the 20th century, however, the production and distribution of food in the developed countries of the ...

Regular physical activity is important for health and has been linked to a reduced risk of numerous chronic diseases.¹ Nonetheless, fewer than half of American adults engage in regular exercise.² A recent federal recommendation regarding regular exercise³ ...

With a record number of applicants to medical schools in the United States in 1995 and concern about a surplus of physicians, it is sometimes forgotten that many people are underserved by the medical profession, particularly the poor, members of minority ...

In late January 1996, President Bill Clinton signed a continuing resolution to keep the government open. Among other things, the resolution prohibits the use of federal funds for research on human embryos.¹ This prohibition, which continues until ...

To the Editor: In the West of Scotland Coronary Prevention Study, reported by Shepherd et al. (Nov. 16 issue),¹ the net benefit of taking pravastatin (40 mg per day for five years), as compared with placebo, was a 2.2 percent reduction in the combined ...

To the Editor: Although the publication of questionable immunocytochemical illustrations — and results — is unfortunately not infrequent, Figure 1 of the article by Baldini et al. (Nov. 23 issue)¹ cannot be ignored, particularly because the conclusions ...

To the Editor: The report by Hillier et al. on vaginal infections and preterm birth (Dec. 28 issue)¹ adds conclusive weight to over a dozen descriptive studies linking bacterial vaginosis and prematurity. The comparatively modest 40 percent increase in ...

To the Editor: Winawer et al. (Jan. 11 issue)¹ found that the siblings and parents of patients with adenomatous polyps are at increased risk for colorectal cancer. The article indicates that 35.6 percent of the polyps studied were larger than 1 cm and ...

To the Editor: Two years ago (Aug. 25, 1994, issue),¹ we reported on two patients who had relief of spinal cord compression after the direct injection of ethanol into a vertebral hemangioma. The improvement in their condition has been maintained for over ...

To the Editor: Disulfiram causes an aversive response to alcohol that is used therapeutically to foster abstinence. There is no similarly effective and safe aversive treatment for cocaine abuse. We report here that flupentixol decanoate can cause ...

To the Editor: Human herpesvirus 8 (HHV-8), also known as Kaposi's sarcoma–associated herpesvirus (KSHV), has recently been proposed as a possible cofactor in the development of Kaposi's sarcoma.¹ Specific sequences of the virus were detected by the ...

One of my most treasured possessions is an old textbook on the examination of the urine by James Tyson, one of the early chairmen of medicine at the University of Pennsylvania (A Guide to the Practical Examination of Urine: For the Use of Physicians and ...

This comprehensive review of renal vascular hypertension in children and adults deals with the various disorders whose final common pathway is renal vascular hypertension. Of particular interest is the account of the pathology and pathophysiology of ...

This is a weighty book — approximately 11 1/4 lb on my bathroom scale. It is cast in the classic form of a large-scale medical reference work, and its size and organization discourage browsing. Consequently, this book is not the best place to seek ...

Unarguably, the specialties of pulmonary and critical care medicine have come a long way in the past quarter of a century. This progress has depended on the application of bioengineering, physiology, biochemistry, pharmacology, molecular biology, and ...