Survivors of acute myocardial infarction are at increased risk for death, recurrent infarction, and unstable angina for many months. Assessing the risk of these events is an important component of subsequent management. The exercise test is the most ...

Signs of parkinsonism¹–³ are frequently found on neurologic examination of older people.⁴–⁹ Although these signs are often considered to be benign concomitants of aging,¹⁰,¹¹ data regarding their prevalence and relation to mortality are derived primarily ...

Hepatitis C virus (HCV), which has a positive-sense, single-stranded RNA genome with approximately 9400 nucleotides, causes most cases of chronic non-A, non-B hepatitis.¹,² Chronic hepatitis C infection can progress to liver cirrhosis and hepatocellular ...

The risk of colorectal cancer in the families of patients with colorectal cancer has been characterized,¹–¹² but it has been less clearly defined for the families of patients with adenomatous polyps.⁷–¹¹ Several studies have provided data supporting the ...

Figure 1. A fracture of a retention wire in an atrial J pacemaker lead (model 330-801, Telectronics, Englewood, Colo.) was detected by chest radiography. The wire, which maintains the J shape of the lead, had fractured, and the distal fragment had ...

Approximately 1 million people in the United States have permanent pacemakers, and 426 new pacemakers were implanted per million members of the population in 1993¹,² (and Bernstein AD, Parsonnet V: personal communication). Since the late 1950s, when the ...

Our understanding of the nature and consequences of upper-airway obstruction in adults during sleep has evolved considerably over the past two decades. Sleep apnea — defined as repeated episodes of obstructive apnea and hypopnea during sleep, together ...

Presentation of Case

A 69-year-old woman was admitted to the hospital because of severe, persistent congestive heart failure after treatment for bacteremia.

The patient had been well until several months earlier, when chronic fatigue developed. Three ...

Reducing morbidity and mortality from coronary artery disease continues to be a major challenge. Many patients with coronary artery disease are asymptomatic or nearly so for long periods, and even when symptoms are present, their severity alone does not ...

It has been more than 20 years since I first learned that I had Parkinson's disease. I had complained for about six months of aching discomfort in my right arm, fairly typical of thoracic outlet syndrome, or so I believed. I was a vascular surgeon, ...

Someone reportedly once teased H.L. Mencken, a proudly self-proclaimed atheist, by asking him if he believed in infant baptism. “Believe in it?” Mencken replied. “Hell, I've seen it with my own eyes.” Were Mencken alive today and asked to comment on the ...

To the Editor: In the recent report from the Nurses' Health Study about the relation between aspirin use and the risk of colorectal cancer (Sept. 7 issue),¹ a key question was whether the investigation inadvertently identified women who were resistant to ...

To the Editor: The thought-provoking results of Pathmanathan et al. (Sept. 14 issue)¹ concerning the role of Epstein–Barr virus (EBV) in nasopharyngeal cancer are of great interest and may have therapeutic implications, especially in areas of the world ...

To the Editor: In their report, Chaisson and colleagues (Sept. 21 issue)¹ suggest that their findings are inconsistent with our finding that lower income at base line was associated with shorter subsequent survival in our cohort of homosexual men ...

To the Editor: Bellet and associates (Sept. 14 issue)¹ report their use of incentive spirometry in patients with painful crises due to sickle cell anemia. They show that patients in crisis had a high incidence of chest-wall involvement. Patients with ...

To the Editor: Administration of praziquantel for 15 days is effective therapy for patients with parenchymal brain cysticercosis.¹ Because the plasma and cerebrospinal fluid concentrations of praziquantel are highest two hours after its administration, ...

To the Editor: One of us, a 40-year-old physician (C.H.R.), decided to take up white-water kayaking. After he had two hours of instruction on flat water, his thumbs and the first two fingers of both hands became numb. He attributed the symptoms to the ...

In July 1995, the U.S. Department of Energy published and posted on the Internet a list of human radiation experiments involving the department or its predecessors. This list was followed in October by the final report of the Advisory Committee on Human ...

Professor Orme of the department of history at Exeter University and his associate Margaret Webster provide an inclusive, scholarly account of the hospitals of England in the clerically dominated centuries before the Reformation. At that historic ...

For anyone interested in the history of medicine, and the history of hospitals in particular, this is an intriguing and entertaining book. Reflecting on hospital care at the turn of the century, we tend to envision long wards with many beds and nurses in ...

In less than a decade, the treatment of mental disorders and substance abuse has undergone a dramatic change with the emergence of for-profit companies that provide managed “behavioral health care.” To the angry dismay of many psychiatrists and other ...

Childhood Dermatomyositis Associated with Hepatocarcinoma Correspondence, N Engl J Med 1995:333;1083.. The figure described in the legend and the text as a computed tomographic (CT) scan is, in fact, a magnetic resonance imaging (MRI) scan.