Hodgkin's disease is likely to have different causes in young adulthood and old age.¹ The characteristic clinical presentation and histopathological appearance suggest that in young adults the disease is initiated by an environmental exposure, possibly to ...

Bartonella quintana, the agent of trench fever, affected about 1 million soldiers during World War I and a smaller number during World War II. Sporadic reports have suggested that infection with this agent, which is transmitted by the body louse, is not ...

Bartonella quintana (formerly known as Rochalimaea quintana ¹) is a fastidious gram-negative bacterium first identified as the cause of louse-borne epidemic trench fever in Europe during World War I.² B. quintana was subsequently recognized as the cause ...

Squamous-cell carcinoma of the head and neck is one of the most common cancers, with a global incidence of 500,000 cases per year.¹ Surgical resection is the principal treatment for the majority of advanced-stage carcinomas of the upper aerodigestive ...

Figure 1. A 50-year-old man had fever, night sweats, and nonproductive cough for 10 weeks. He took antipyretic medications during the febrile periods. His wife recorded his temperatures, shown above, on 56 of the 71 days. Biopsy of a rapidly enlarging ...

The metaphor of domestic violence as chronic disease is a useful one for clinicians. Studies of domestic violence over the life span suggest that, like many ongoing illnesses that are typified by periods of quiescence and exacerbation, abuse is more often ...

Exposures to blood-borne pathogens pose a serious occupational threat to health care workers. Safer needle devices for performing phlebotomy and other procedures and universal infection-control precautions will not completely eliminate the risk, and ...

Presentation of Case

A 73-year-old right-handed man was admitted to the hospital because of weakness, drowsiness, headache, and confusion.

The patient had been well until four weeks earlier, when fatigue, anorexia, somnolence, confusion, and a severe, ...

Hodgkin's disease has been thought by some to be an infectious or inflammatory disease, but the Reed–Sternberg cells characteristic of the disorder are monoclonal and aneuploid and can form tumors in immunocompromised animals — characteristics of a ...

To those unfamiliar with the disease the man who has never been in the trenches cannot be suffering from trench fever, and for this reason the spread of the disease to new districts, and among those unfamiliar with its symptoms, will go unrecognised. . . ...

The demise of federal legislation to reform our health care system has frustrated the hopes (or quieted the fears) of millions of Americans. Nevertheless, the problems of our health care system persist, and efforts to reform it will proceed at several ...

To the Editor: . . . In the study by Mark et al. (Oct. 27 issue),¹ I am struck by the large difference between Canada and the United States in the use of invasive diagnostic and therapeutic procedures in patients with acute myocardial infarction, despite ...

To the Editor: The study of differences in knowledge between cardiologists and primary care physicians by Ayanian and colleagues (Oct. 27 issue)¹ raises interesting questions. The authors assume that the results of the studies they cite are valid, that ...

To the Editor: In your recent editorial “Access to Specialty Care” (Oct. 27 issue),¹ you mention informal, unofficial “sidewalk” or telephone consultations. Many physicians refer to such consultations as “curbsides.”¹ These consultations save health ...

Sheila Rothman's new book is an important contribution to the growing body of scholarly literature devoted to an understanding of the history of medicine from the patient's perspective. With an approach that is self-consciously interdisciplinary — ...

This book is a unique collection of information about what some now call vaccinology. Its 35 chapters include the epidemiologic and clinical studies leading up to the licensure of vaccines currently in use and pay some attention to newer approaches to ...

It is difficult to summarize this book, because it is more than a history of obstetrics and gynecology — and also less. History can be written in different ways and for different reasons. The authors never define their goals, and this lack of definition ...

This ambitious textbook covers the entire scope of clinical maternal–fetal medicine. High Risk Pregnancy: Management Options distinguishes itself from other standard perinatology textbooks, such as Maternal–Fetal Medicine: Principles and Practice (edited ...

Without question, the technological revolution of the past two decades has elevated the fetus to the level of the corecipient of obstetrical health care. Thus, The Fetus as a Patient, edited by Asim Kurjak, M.D., and Frank A. Chervenak, M.D., is a timely ...

Radiofrequency Catheter Modification of Atrioventricular Conduction to Control the Ventricular Rate during Atrial Fibrillation Original Article, N Engl J Med 1994:331;910-917.. On page 915, in lines 10 through 12 of the left-hand column, the workloads ...