Previous studies have suggested that higher intakes of vitamin E (alpha-tocopherol) and beta carotene may be associated with a reduced risk of lung cancer. In particular, epidemiologic studies have linked the intake of vegetables rich in beta carotene ...

Acetylcholine relaxes intact blood vessels by means of muscarinic receptors that stimulate the synthesis and release of an endothelium-derived relaxing factor (EDRF)¹. EDRF is identical to nitric oxide²,³ or very closely related to it. Nitric oxide ...

During the past 20 years, the role of family history in early-onset coronary heart disease in men has been well established¹–¹⁴. However, only a few prospective studies have investigated the influence of familial factors on this disease in women¹⁵,¹⁶. ...

The cervical zygapophyseal joints, which are paired synovial joints between the neural arches of the cervical vertebrae, are a common source of chronic post-traumatic neck pain¹. Uncontrolled observations have suggested that the intraarticular injection ...

The number of cases of tuberculosis in women of childbearing age increased 41 percent in the United States between 1985 and 1992 (Centers for Disease Control and Prevention [CDC]: unpublished data). The risk of tuberculosis in pregnancy has probably also ...

Figure 1. Acid-Fast Organisms.

A bone marrow-biopsy specimen, stained by the Ziehl-Neelsen technique (x1000), was obtained from a 47-year-old man with the acquired immunodeficiency syndrome who presented with a high fever and pancytopenia. The small ...

That positive-pressure mechanical ventilation can save lives was proved during the poliomyelitis epidemics of the 1950s¹. Since that time there has been a growing increase in the use of ventilatory support, and it has been closely associated with the ...

Many postmenopausal women have been treated with ovarian hormones in an attempt to alleviate the symptoms of menopause and, more recently, in the hope of preventing osteoporosis and reducing the risk of ischemic heart disease. The postmenopausal period ...

Presentation of Case

A 14-year-old girl was admitted to the hospital because of biochemical features of advanced renal failure.

The patient had been apparently well and active until two months earlier, when she began to experience fatigue after exercise, ...

Over the past decade, there has been increasing scientific and public interest in the theoretical possibility that antioxidant vitamins, such as beta carotene (provitamin A)¹ or more recently alpha-tocopherol (vitamin E),² might help prevent cancer or ...

Cardiovascular disease accounts for considerable mortality and morbidity in Western countries. Most of the common forms of cardiovascular disease, such as atherosclerosis, are caused by functional and structural changes in the blood-vessel wall. These ...

Whiplash injuries occur in more than 1 million people in the United States every year¹. Although the majority become asymptomatic in a matter of weeks to a few months, 20 to 40 percent have symptoms that are sometimes debilitating and persist for years. ...

To the Editor: In their article “Professional Courtesy -- Current Practices and Attitudes” (Nov. 25 issue),¹ Levy et al. do not mention an important point. To be asked to treat one's colleague or his or her family is the greatest honor bestowed on a ...

To the Editor: Despite its impressive scope and detail, Starr's description of the Health Security plan (Nov. 25 issue)¹ neglected a key element of health care reform: the content of the federally mandated minimal-benefit package. Its content will ...

To the Editor: In their review of rabies (Nov. 25 issue),¹ Fishbein and Robinson state that persons who have not been vaccinated before possible exposure to rabies should be given rabies immune globulin as a component of prophylaxis, whereas persons who ...

To the Editor: The GUSTO (Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries) angiographic investigators (Nov. 25 issue)¹ concluded that normal coronary flow in the infarct-related artery early after ...

To the Editor: In the November 18 issue of the Journal, Dann et al.¹ reported a case of tumor lysis syndrome after treatment with 2-chlorodeoxyadenosine (cladribine) in a patient with refractory chronic lymphocytic leukemia. We would like to report ...

To the Editor: The report by Neumann et al. (Nov. 18 issue)¹ underscores the importance of screening for hereditary disorders in patients with pheochromocytoma. The authors' determination, however, that 23 percent of unselected patients with ...

To the Editor: Congenital erythropoietic porphyria is a defect of uroporphyrinogen III synthase, with accumulation of uroporphyrin I, extreme hemolysis, and photosensitivity¹,². We previously reported the effectiveness of aggressive transfusion in a ...

To the Editor: Congenital erythropoietic porphyria is a rare autosomal recessive disorder with progressive photomutilation and hemolysis due to excessive porphyrin production. Published studies have shown that oral treatment with activated charcoal to ...

To the Editor: We wish to describe what initially appeared to be a right orbital pseudotumor and was ultimately discovered to be an embedded conjunctival foreign body causing a granulomatous reaction.

The mother of a four-year-old noted swelling in the ...

I hate Bosco,

It's full of DDT.

Mommy put it in my milk to try to poison me.

But I fooled Mommy, I put some in her tea.

Now there's no more Mommy to try to poison me.

-- Children's rhyme

The accessibility and power of poisons make them common and ...

Adolescent health care is coming of age as a new medical subspecialty. Several new textbooks have recently been published, a testament to the need for physicians to understand better this unique population, wedged between conventional pediatrics and ...

This is an extremely thorough encyclopedia of gynecology, covering everything from the embryology and anatomy of the female genital tract to the diagnosis and treatment of benign and malignant diseases of women. It has a special focus on pregnancy ...

Operative Gynecology contains 33 chapters by 48 authors, all but 2 of whom are from the United States. It is organized along traditional lines with an anatomically based approach to both benign and malignant gynecologic conditions and includes a useful ...

A book crystalizing fundamental aspects of the normal and abnormal menstrual cycle is an invaluable addition to the library of any primary care physician. Understanding the events of the menstrual cycle, and the fluctuations in gonadotropin and sex-...

Adashi and Leung have compiled an outstanding group of chapters by leading authorities on the physiology, molecular biology, and clinical disorders of the ovary. Their book is an invaluable compendium for serious students. Each chapter extends the breadth ...