Tetralogy of Fallot (obstruction of right ventricular outflow, ventricular septal defect, right ventricular hypertrophy, and an overriding aorta) is the commonest cause of cyanotic congenital heart disease worldwide. It is estimated to occur in ...

Differences between blacks and whites have been reported for the prevalence of many cardiovascular diseases, such as hypertension, renal failure, and stroke¹. In the case of cardiac arrest, however, there is a paucity of data and conflicting results²–⁸. ...

To reduce the risk of Rh alloimmunization in a subsequent pregnancy, RhD-negative women are given anti-RhD antibodies after miscarriage, the birth of an RhD-positive baby, or any obstetrical procedure that may cause fetomaternal hemorrhage. As a result, ...

Although the autonomic nervous system has a recognized role in the maintenance of sodium and water balance and the regulation of plasma volume, little is known about its role in the regulation of red-cell volume. This question is of interest because some ...

Until recently, evidence of a relation between plasma renin activity and the risk of major coronary events has come largely from prevalence or cross-sectional studies. In 1972, Brunner et al.¹ suggested that high levels of plasma renin activity in ...

Figure 1. Endovascular Stents for Iliac Arterial Disease.

The angiogram shown in Panel A was recorded in a 57-year-old man with no right femoral pulse; arrows indicate a 5-cm total occlusion of the right common iliac artery. The occlusion was crossed with ...

Access to technologically advanced care for certain segments of society is an important health care issue in the United States¹. Previous studies have found racial differences in the use of invasive procedures in the management of cardiac disease²–⁸. ...

Mood Disorders

Mood disorders include the depressive and manic states and are often intertwined with irritability, anger, emotional upheaval, and anxiety. The disorders may be associated with substance abuse, alcoholism, eating disorders, medical illness, ...

American trypanosomiasis (Chagas' disease) is a zoonosis caused by the protozoan parasite Trypanosoma cruzi¹,². As is typical of tropical diseases, it is a major cause of morbidity and mortality among poor people in developing countries, but health care ...

Presentation of Case

A 36-year-old man with the acquired immunodeficiency syndrome (AIDS) was admitted to the hospital because of increasing dyspnea and respiratory failure.

The patient was homosexual; his companion was known to have human ...

There are approximately 500,000 adults with congenital heart disease in the United States, and each year another 10,000 children who have undergone surgical repair reach adulthood¹. The largest diagnostic category among patients undergoing repair is ...

Despite the dismantling of legal barriers that enforced segregation and limited opportunity for black Americans, racial disparities persist in all areas of American society¹. Health care is no exception. Two studies in this issue of the Journal²,³ ...

Hemolytic disease of the newborn occurs as a result of sensitization of the mother's immune system to red-cell antigens of the fetus. This sensitization results from the transplacental passage of fetal red cells possessing an antigen that is not present ...

To the Editor: The report by Komaromy et al. (Feb. 4 issue)¹ on sexual harassment in medical training has given a high profile to a problem that many have chosen to ignore. We conducted a descriptive, cross-sectional survey of full-time faculty and ...

To the Editor: Patterson et al. (Feb. 18 issue) question whether patients with cervical-level quadriplegia should ever be allowed to refuse life support early in their care¹. This includes the acute phase in the intensive care unit, a period that can ...

To the Editor: In their discussion of graft-versus-host disease (GVHD) associated with the transfusion of blood from unrelated HLA-homozygous donors, Shivdasani et al. (March 18 issue)¹ cite data indicating that the risk of transfusion of blood from HLA ...

To the Editor: The Food and Drug Administration, after receiving 6 reports of benign intracranial hypertension (pseudotumor cerebri) in patients treated with recombinant growth hormone, actively identified an additional 17 affected patients in the United ...

To the Editor: In their article (March 4 issue), Welch et al. analyze geographic variations in expenditures for physicians' services in the United States¹. They cite a positive correlation between age-adjusted mortality among Medicare patients and the ...

To the Editor: Exposure of the fetus to cocaine may lead to serious destructive lesions in the brain¹–³. Results of brain imaging studies in newborns have revealed that ischemic cerebral lesions may occur, leading to clinical manifestations when large. ...

Periodically, another Cassandra publishes more bad news about the health of African Americans. No one likes to see it coming because, short of eliminating racism or overhauling the health care system, there seems so little one can do about it.

This book ...

The title of this book is misleading, for there is little in it on the subject of clans. Its subtitle, “The Influence of Human Relationships on Heart Disease,” is more informative, since the subject is the authors' study of heart disease and human ...

The concepts of community-oriented primary care and medical anthropology have been with us for more than 30 years, yet rarely do we see work that combines the two successfully. In this book, the author reports on a Yemenite immigrant community with which ...

Books devoted entirely to a comprehensive study of sickle cell anemia are few in number, so a new book is to be welcomed. As in many multiauthored books, the chapters vary in quality and usefulness and tend to be repetitive in their introductions, but on ...

The rhetoric of health care reform now bombards us daily, with the often unspoken message that once there is universal health insurance, the health problems of America's vulnerable populations will cease to exist or to be matters of concern. Two recent ...

Reducing Mortality from Colorectal Cancer by Screening for Fecal Occult Blood Original Article, N Engl J Med 1993:328;1365-1371.. On page 1370, in Table 6, the second footnote should have read, “Sensitivity was defined as the number of true positive ...