Although digitalis has been used for more than 200 years, its role in the treatment of chronic heart failure has been highly controversial. For many years, the debate surrounding digitalis was focused on the question of its usefulness in patients with ...

Cat scratch disease was first described more than 40 years ago¹. Its classic clinical feature is self-limited, regional lymphadenopathy occurring after a cat scratch or bite distal to the affected node. The etiologic agent has not been conclusively ...

Diarrhea is a common complication in immunocompromised persons infected with human immunodeficiency virus type 1 (HIV-1), occurring in 30 to 60 percent of North American and European patients and in nearly 90 percent of patients in developing countries¹–⁹...

To reduce blood cholesterol levels and prevent coronary heart disease, major agencies recommend reduced consumption of saturated fat and cholesterol¹,² and increased intake of carbohydrate foods high in fiber, especially soluble fiber. One benefit of ...

Non-Hodgkin's lymphoma after organ transplantation is a recognized complication of immunosuppressive therapy. A number of cases of post-transplantation lymphoma arising in allografted tissue have been described¹. In addition, leukemia and lymphoma arising ...

Figure 1. Neurocardiogenic (Vasodepressor) Syncope.

A 72-year-old woman with breast cancer that had metastasized to the glossopharyngeal region had recurrent episodes of sudden lightheadedness, diaphoresis, and syncope. A dual-chamber pacemaker was ...

The growing popularity of travel to the tropics (more than 9 million tourists arrive in Africa each year and more than 32 million in Asia and the southwestern Pacific region¹) is placing an increasing number of travelers at risk for acquiring malaria. The ...

Stage

A 72-year-old man was sent to the emergency room by a visiting nurse, who had found him at home in respiratory distress. He had a two-week history of malaise, anorexia, dyspnea, and chest pain.

Response

My primary concern is to determine the cause ...

Presentation of Case

A 73-year-old man was admitted to the hospital with a diagnosis of a contained, ruptured aneurysm of the left femoral artery.

The patient was a retired shipyard pipe fitter, with known exposure to asbestos. He had smoked one pack of ...

Many people gasped several weeks ago when Boston Celtics captain Reggie Lewis slumped to the parquet floor during a playoff game at Boston Garden. In part, their memory of Hank Gathers, the college basketball star who only three years earlier collapsed ...

Although two centuries of anecdotal clinical evidence support the use of cardiac glycosides for the treatment of heart failure, controversy has surrounded their efficacy and appropriate indications. Early in this century, two of the founders of the ...

Although cat scratch disease was first recognized more than 60 years ago, only in the past few years has real progress been made in identifying the microbes that cause this disorder. The diagnosis of cat scratch disease has relied on several criteria: a ...

Recently, there has been growing interest in the problem of cardiovascular disease in young athletes. Some of the compelling issues are the causes of sudden cardiac death during physical exertion, the appropriateness and practicality of cardiovascular ...

To the Editor: A problem with the study by Fan et al. (Jan. 28 issue)¹ is the authors' inability to distinguish reliably patients presenting with acute pancreatitis and secondary biliary obstruction from those presenting with primary biliary obstruction ...

To the Editor: Hentschel et al. (Feb. 4 issue)¹ discuss the effect of ranitidine and amoxicillin plus metronidazole on the eradication of Helicobacter pylori and the recurrence of duodenal ulcer. They conclude that the combination of amoxicillin and ...

To the Editor: Protein-losing hypertrophic gastropathy is a life-threatening disease characterized by hypoproteinemia,¹ often with the development of gastric cancer². In a retrospective study of 138 patients, we found that hypertrophic gastropathy was ...

To the Editor: Miles et al. (Feb. 4 issue)¹ suggest that the immune-complex-dissociated HIV p24 antigen assay may be of value in the early diagnosis of pediatric human immunodeficiency virus (HIV) infection. We do not believe that the data they present ...

To the Editor: Mooren's corneal ulcer is a chronic, painful, progressive disorder that characteristically affects the peripheral cornea in a circumferential manner¹. The disease may be unilateral or bilateral and may progress to involve the entire cornea,...

To the Editor: Moore et al. (Dec. 17 issue)¹ reported that plasma endothelin concentrations were elevated in patients with the hepatorenal syndrome, but they provided no data indicating that endothelin may cause the renal dysfunction. Was the glomerular ...

To the Editor: Skoog et al. and Larson (Jan. 21 issue)¹,² emphasize that a lack of diagnostic criteria is one of the major reasons for the paucity of epidemiologic studies of vascular dementia. To address this problem, the National Institute of ...

To the Editor: Dr. Modell's discussion of drowning (Jan. 28 issue)¹ was extremely informative. In the article he concluded that prevention is the best solution to the problem of drowning among children. Unfortunately, there is no evidence that early ...

How do we care for the elderly? How should we care for the elderly? These two books examine these questions, providing some insights yet raising more issues of concern for professionals who provide care, administer programs, or develop policy for elderly ...

Since 2 million elderly people are receiving medical care in 19,000 nursing homes, it is appropriate and timely to devote careful thought to optimizing the care of nursing home residents. Medical Care in the Nursing Home is a distinguished contribution to ...

Dementia poses an enormous ethical problem to U.S. society and to other societies and cultures in the world. The “old old” are the fastest-growing segment of our population, and dementia is alarmingly prevalent in this group. The most common dementias are ...

This book is the first of a series that is planned to review new knowledge about Alzheimer's disease and other adult-onset dementias, with particular emphasis on less well known topics. This book discusses the scientific bases of innovative approaches to ...

This book appears to have two goals. The first is to supply physicians with useful information that allows them to recognize common endocrine conditions in older patients and special problems in the diagnosis and treatment of diseases in this population. ...

The topic of this book -- the pharmacology of drugs used in elderly patients -- is an important one. Because the aging process modifies the metabolism and clinical effects of some medications, elderly patients are susceptible to adverse drug reactions, ...

There is an ever-growing number of elderly patients in the United States and the United Kingdom. It is estimated that by the year 2025, 16 percent of the U.S. population will be over the age of 65. As the population ages, the elderly represent a larger ...

Age-related macular degeneration is the main cause of legal blindness in developed nations. It is already a major health problem, and with the continuous increase in our aging population, the number of affected patients will grow. Although numerous ...

Case Records of the Massachusetts General Hospital (Case 19-1993) Case Records of the Massachusetts General Hospital, N Engl J Med 1993:328;1406-1414.. On page 1406, in the left-hand column, the sentence beginning on line 14 should have read, “A computed ...