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December 31, 1992  Vol. 327 No. 27

Original Articles
1893-1898

MORE than 30 million Americans are obese, and many require medical care for diabetes, high blood pressure, and hyperlipidemia.1 Some obese subjects seek medical evaluation for failure to lose weight despite a history of severe caloric restriction. These ...

1899-1905

ONE of the most important features of non-A, non-B hepatitis is the frequency with which chronic liver disease develops. Most studies of chronic non-A, non-B hepatitis have been follow-up studies of patients who have received transfusions. An average of ...

1906-1911

NON-A, NON-B HEPATITIS was recognized in the mid-1970s during the course of several prospective studies of transfusion-associated hepatitis in the United States.1 2 3 4 5 6 7 These studies found an incidence of hepatitis ranging from 7 to 17 percent, 78 ...

1912-1918
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HYPERTENSION occurs in up to 80 percent of patients with chronic renal failure and is a major risk factor for the excessive cardiovascular morbidity and mortality among these patients.1 2 3 However, the underlying causes of this hypertension are not fully ...

1919-1923
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IN tertiary care centers, up to 10 percent of all patients with idiopathic peripheral neuropathy have an underlying plasma-cell dyscrasia.1 , 2 Osteosclerotic myeloma is a plasma-cell dyscrasia characterized by sclerotic bone lesions and progressive ...

1924-1926

ORGAN-TRANSPLANT recipients are prone to the development of cutaneous and extracutaneous malignant tumors.1 , 2 Lymphomas occur in 1 to 2 percent of graft recipients and are usually of the B-cell type.3 Cutaneous T-cell lymphomas are extremely rare. We ...

Images in Clinical Medicine
1927
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Panel A shows massive obesity of the lower legs of a 64-year-old woman. Note the bilateral symmetric, nonpitting swelling of the legs with sparing of the feet, which can be mistaken for lymphedema. In Panel B, a radionuclide lymphangiogram taken 30 ...

Review Article
1928-1937

    ASTHMA is a chronic illness that causes widespread narrowing of the tracheobronchial tree. The disease is characterized by acute exacerbations of varying degrees of severity that resolve spontaneously or with therapy. In unusual circumstances acute ...

    Case Records of the Massachusetts General Hospital
    1938-1946

    Presentation of Case

    A 71-year-old man was admitted to the hospital because of a suspected exacerbation of chronic obstructive pulmonary disease.

    The patient had smoked three packs of cigarettes daily for 20 years and stopped 28 years before entry. ...

    Editorials
    1947-1948

      Lichtman et al. report in this issue of the Journal 1 that a subgroup of obese subjects whom they identified as resistant to dieting have failed to lose weight because they eat more and exercise less than they think. Doubly labeled water was used to ...

      1949-1950

      The existence of non-A, non-B hepatitis was deduced in the mid-1970s when the new serologic tests for hepatitis B virus infection could not explain a substantial proportion of the cases of transfusion-associated hepatitis.1 Subsequent studies showed that ...

      Correspondence
      1951-1953

      To the Editor: Haddow and colleagues (Aug. 27 issue)1 reported that the use of three maternal markers improved the efficacy of prenatal screening for Down's syndrome. We think that the exact gestational age should be determined by ultrasonography before ...

      1953

      To the Editor: Infection with the hepatitis B virus (HBV) has been a serious problem for residents of institutions for the developmentally handicapped.1 The recently discovered2 hepatitis C virus (HCV) has similar risk factors, but the prevalence of ...

      1953-1955

      To the Editor: Dr. Byrne's fine review of spinal cord compression from epidural metastases (Aug. 27 issue)1 demonstrates how frustrating the treatment of this disease can be. The treatment of patients with neurologic symptoms from epidural metastases has ...

      1955-1956

      To the Editor: We have two areas of concern about the data on cysticercosis presented by Vazquez and Sotelo (Sept. 3 issue).1 First, the findings they report for groups 1 and 2 (patients with lesions without inflammation) are inconsistent with other data ...

      1956

      To the Editor: I wish to describe how recurrent pneumothorax led to the diagnosis of pulmonary leiomyomatosis in a young woman receiving hormone-replacement therapy. Uterine leiomyomas found in the lung were first reported by Steiner.1 The phenomenon is ...

      1956-1957

      To the Editor: In his article on managed care (Sept. 3 issue),* Iglehart discusses the challenge of identifying cost-effective physicians. Whereas many debate the appropriateness of selecting physicians on the basis of the numbers, managed-care entities, ...

      Book Reviews
      1958

      This is an encyclopedic textbook whose purpose is to describe the diagnosis, evaluation, and treatment of the medical and obstetrical complications of pregnancy as they affect the mother and the fetus. It begins with conception and ends with the newborn ...

      1958-1959

      Effective medical writing informs and challenges, and both tasks are equally important. Nowhere is this more critical than in the field of perinatal care, which is now under intense medical and legal scrutiny. There are three components of any adverse ...

      1959

      In the mid-1920s, Hans Hinselmann of Hamburg, Germany, described the technique of examining the cervix with a high-powered series of lenses and a bright light. Thus, the technique of colposcopy was inaugurated. For a multiplicity of reasons, it was not ...

      1960

      Fetal Doppler imaging has stirred up intense interest in perinatology. Meetings are devoted to the subject, more articles appear with the arrival of each obstetrical journal, and countless abstracts have been submitted to conferences. We have been able to ...

      1960-1961

      The Pill, Pygmy Chimps, and Degas' Horse is a formidable title for any book. I shall remember the book, but never the title. Dr. Djerassi has led a remarkable life and has put together a readable autobiography. He has been credited, along with at least ...

      1961

      The management of gynecologic neoplasms has become increasingly multidisciplinary over the past decade. In addition, the contribution of the basic scientist is becoming increasingly important in developing clinical strategies. This book effectively ...

      Books Received
      1962-1963

      Medicine

      Rheumatology Examination and Injection Techniques. By Michael Doherty, Brian L. Hazleman, Charles W. Hutton, Peter J. Maddison, and J. David Perry. 135 pp., illustrated. Philadelphia, W.B. Saunders, 1992. $40. ISBN 0–7020–1442–7.

      Saunders Review ...

      Notices
      1964

      CALL FOR NOMINATIONS

      Nominations are being accepted for the "1993 Healthtrac Prize for Improvement of Health." Deadline for submission is May 3.

      Contact Dr. James F. Fries, Healthtrac Fdn., 525 Middlefield Rd., Suite 250, Menio Park, CA 94025; or call (...