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September 3, 1992  Vol. 327 No. 10

Original Articles
669-677

SURVIVORS of acute myocardial infarction are at a greatly increased risk for subsequent fatal and nonfatal cardiovascular events.1 This heightened risk is influenced by many factors, the most important of which is the severity of left ventricular ...

678-684

BOTH the short-term and the long-term prognosis for patients with acute myocardial infarction has improved in recent years with the use of beta-adrenergic blockers, thrombolytic agents, and aspirin.1 Mortality not prevented by these treatments is related ...

685-691

ANGIOTENSIN-converting—enzyme inhibitors reduce mortality and the need for hospitalization and improve functional status in patients with symptomatic congestive heart failure.1 2 3 Despite such treatment, however, the mortality and morbidity rates ...

692-695

NEUROCYSTICERCOSIS is an infection of the central nervous system with the larval forms (cysticerci) of the pork tapeworm Taenia solium. The two-host life cycle of the tapeworm involves humans as definitive hosts and swine as intermediate hosts. Pigs are ...

696-701

EPILEPSY is a common sign of a brain abnormality; however, little is known about its outcome when the primary cause is removed.1 2 3 4 5 6 7 8 9 10 In the case of epilepsy due to neurocysticercosis, the epileptogenic area is in the brain tissue that ...

702-706

SEVERAL renal syndromes have been described in patients with human immunodeficiency virus (HIV) infection. The most common renal abnormality is focal segmental glomerulosclerosis,1 2 3 but some patients have evidence of immune-complex nephropathy,1 2 3 ...

Review Article
707-713

DIABETES mellitus is characterized by both fasting hyperglycemia and exaggerated postprandial increases in the plasma glucose level. Understanding the causes of these abnormalities is important for the rational use of current treatments and for developing ...

Clinical Problem-Solving
714-717

    A 70-year-old man was referred to a cardiologist for evaluation of exertional chest pain and dyspnea.

    The first thing that comes to mind in a man in this age group with exertional chest pain and dyspnea is the possibility of myocardial ischemia, most ...

    Case Records of the Massachusetts General Hospital
    718-724

      The following is a list of reference values, general methods, and conversion factors for tests commonly ordered at the Massachusetts General Hospital and recorded in the Case Records. It reflects the revision of tabular summaries previously published (...

      Editorials
      725-727

      Chronic congestive heart failure is often a lethal disease. Even though clinical trials have documented improved survival when enalapril1 2 3 or hydralazine plus isosorbide dinitrate3 , 4 was added to digoxin and diuretic therapy, more than 40 percent of ...

      727-728

      A diagnosis of neurocysticercosis, commonly caused by the larva of the pork tapeworm, Taenia solium, is rare enough to qualify for presentation at grand rounds in most medical centers throughout the United States. However, in Latin America and South ...

      729-730

        In 1984, a distinct nephropathy was described in patients with the acquired immunodeficiency syndrome (AIDS) in New York and Miami. The nephropathy is typically characterized by a severe nephrotic syndrome. The proteinuria can be of sudden onset and can ...

        Correspondence
        731-732

        To the Editor: Dr. Eisenberg's impressive plea for primary care physicians to treat depression and anxiety (April 16 issue)* echoes sentiments expressed by official organizations in family medicine, internal medicine, and pediatrics. The largest ...

        732-734

        To the Editor: I had hoped that Cunningham and Lindheimer, in their review of hypertension during pregnancy (April 2 issue),1 would revise the statement, made in an earlier article by Lindheimer and Katz,2 that epidural anesthesia should be avoided in ...

        734-735

        To the Editor: The patients with uremic pruritus who were treated with erythropoietin in the study by De Marchi et al. (April 9 issue)1 had not only a decrease in the severity of pruritus and lower plasma histamine concentrations but also a modest ...

        735

        To the Editor: In their study of the use of thalidomide in the treatment of graft-versus-host disease (GVHD), Vogelsang et al. (April 16 issue)1 minimize the seriousness of thalidomide neuropathy. Follow-up studies of patients who took thalidomide as a ...

        735-736

        To the Editor: Geisler et al. reported (June 27, 1991, issue) that monosialotetrahexosylganglioside (GM-1) ganglioside produces improvement when injected up to 72 hours after a spinal-cord injury.1 The Food and Drug Administration has made special ...

        736

        To the Editor: The adverse effects that occur in transplant recipients treated with the monoclonal antibody OKT3 include chills, fever, headaches, digestive symptoms, and occasionally pulmonary edema, aseptic meningitis, and even intragraft thromboses.1 ,...

        737

        To the Editor: Since May 1990, at the request of the Ministry of Health of the U.S.S.R., now the Ministry of Health of Russia, the Maine Academy of Family Physicians has been working to help develop family medicine as a specialty in Russia. Since ...

        737-738

        To the Editor: In the recent Clinical Problem-Solving article by Duffy (April 2 issue),* the expert clinician states that it would be best to withdraw nutrition from the dying patient but to continue hydration, because it has "important symbolic meaning."...

        Book Reviews
        738-739

        Nelson Textbook of Pediatrics is a venerable mainstay of American pediatrics. Now in its 14th edition, the textbook, edited by Richard E. Behrman and others, has chapters contributed by 137 authors. The editors have followed the traditional format of ...

        739

        In the late 1920s, a young Canadian student doing graduate work in London developed an interest in collecting feeding bottles and other objects related to the nutrition of infants. After Theodore Drake obtained his bachelor of medicine degree in 1914, he ...

        739-740

        Dysmorphology, the identification of birth-defect syndromes, involves a method of pattern recognition that is similar to the interpretation of histologic slides or radiographic images. The diagnosis is discerned through an understanding of normal and ...

        740

        The author says in the preface that "visual recognition is a major factor in making the correct diagnosis." Therefore, the main appeal of an atlas is its pictures and illustrations, with the text merely for augmentation or clarification. In many of the ...

        740

        Pediatric rheumatology has only recently emerged as a distinctive specialty with its own subspecialty boards. Its beginnings can largely be traced to the Canadian Red Cross Memorial Hospital in Taplow, England, which was the site of a rheumatic research ...

        740-741

        This atlas comprises photographs, light and electron micrographs, radiographs, and other pictorial material that illustrate various aspects of common and exotic pediatric infections. Chapters are organized according to organ system, with illustrative ...

        741-742

        One of the joys of pediatric cardiology is the formulation of a clinical impression based only on the history and cardiovascular examination, perhaps supplemented by an electrocardiogram and a chest x-ray. For cost-effectiveness and efficient use of ...

        Notices
        742

        ASSOCIATION FOR THE ADVANCEMENT OF MEDICAL INSTRUMENTATION

        The following will be offered: "Support of Anesthesia Delivery Systems" (Dallas, Sept. 20–22); "Clinical Engineering Management Seminar (Advanced)" (San Diego, Calif., Oct. 29 and 30); "Mid-Year ...

        Health Policy Report
        742-747

        America's private and public third-party payers, squeezed by health care costs that continue to soar at rates well above inflation, are persuaded that "managed care" plans will produce demonstrable savings as compared with the current cost trends of ...

        Information for Authors
        748

        These guidelines are in accordance with the "Uniform Requirements for Manuscripts Submitted to Biomedical Journals." (The complete document appears in the February 9, 1991, issue of the British Medical Journal and the February 7, 1991, issue of the New ...