CORONARY heart disease is a leading cause of morbidity and mortality in the United States among both men and women. Since 1950, the incidence of coronary heart disease has risen among women while it has declined among men.¹ Major advances in diagnosis and ...

CORONARY artery disease is the leading cause of death in women. It is estimated that 500,000 women die of the disorder each year, a mortality rate in this group that exceeds that for all neoplastic diseases combined.¹ However, several lines of evidence ...

PERINATAL growth failure is common among infants with very low birth weights (<1.5 kg). In 1977 we initiated a prospective study of the effects of very low birth weight and associated growth failure on outcome. We showed that head size at the age of eight ...

INTRATHYROIDAL lymphocytic infiltrates have recently been characterized in human autoimmune thyroid disease.^{1 2 3} The majority of such cells are T lymphocytes, and there is extensive selection of particular T-cell subgroups, as determined by their surface ...

THE frequency of malpractice claims among patients injured by medical negligence has been the subject of much speculation and little empirical investigation. Two fundamental questions about malpractice litigation have been how well it compensates patients ...

DURING the past two decades viral causes of gastroenteritis have been uncovered for the first time, and viruses have joined bacteria and parasites as recognized pathogens involved in medically important diarrheal disease. For example, rotavirus is now ...

Presentation of Case

An 85-year-old woman was admitted to the hospital because of progressive impairment of renal function, neurologic deterioration, and seizures.

The patient was in excellent health and appeared well when visited by her family in the ...

Yentl, the 19th-century heroine of Isaac Bashevis Singer's short story,¹ had to disguise herself as a man to attend school and study the Talmud. Being "just like a man" has historically been a price women have had to pay for equality. Being different from ...

Each year approximately 45,000 infants with very low birth weights are born in the United States, and approximately 80 to 85 percent survive the neonatal period. All too often, these survivors have overt motor deficits (cerebral palsy) or substantial ...

Autoimmune diseases are characterized by the persistent activation of immunologic effector mechanisms that alter the function and integrity of individual cells and organs. This process of abnormal self-reactivity may be initiated by environmental agents, ...

To the Editor: Ziegler and collaborators (Feb. 14 issue)¹ recently reported on an impressive reduction in 28-day mortality, from 49 percent to 30 percent, in a subgroup of patients who had bacteremia due to gram-negative bacilli. The patients were ...

To the Editor: The article by Pizarro et al. on rice-based oral electrolyte solutions for the management of infantile diarrhea (Feb. 21 issue)¹ presents several problems for me as a clinician treating gastroenteritis and dehydration. First, the article ...

To the Editor: Human T-cell lymphotropic virus Type I (HTLV-I) is the etiologic agent of adult T-cell leukemia and a chronic neurologic syndrome. The only known modes of transmission of this virus are from mother to child, predominantly through breast ...

To the Editor: Recombinant human erythropoietin (Epogen) is widely used in patients on dialysis to correct the anemia of chronic renal failure. I wish to draw attention to the observation during the past year of five patients on hemodialysis who had ...

To the Editor: The report by Iwasaki et al. (Feb. 21 issue)¹ of aggravation of diabetes insipidus during pregnancy extends our knowledge of this phenomenon,^{2 3 4 5 6 7} confirming that it may be either responsive or resistant to vasopressin. We wish to ...

To the Editor: Your readers should be aware of four errors related to the following statement from the article by Prinz et al. (Aug. 23 issue).¹ "In elderly patients in whom sundowning occurs in the context of delirium associated with withdrawal from ...

The watch on her wrist Caught my eye And touched my heart

I was the doctor Examining the patient

Eighty-two years old Looks like sixty Walks like fifty Talks like forty Touches her toes like thirty With the enthusiasm That those at twenty Should have

But ...

I have had the good fortune to be asked once again to review a new edition of Best and Taylor for the Journal. In my review of the 11th edition (N Engl J Med 1985; 313:189) I stated that the book was "a good starting point for medical students and an ...

How does one review adequately the 43rd edition of an enormously popular therapeutic guide that contains 291 chapters by more than 300 clinical experts? Rather than attempt to skim a smattering of this huge book, we chose instead to review a selected ...

A clear understanding of the gas-exchange properties of the lung is vital for anyone with more than a casual interest in respiratory physiology. The interrelations among ventilation, lung blood flow, and attendant respiratory gas exchange are among the ...

Like most things, textbooks fall into categories. There are textbooks of internal medicine, physiology, pathology, and clinical chemistry, each directed toward a particular audience. Books that attempt, like this one, "to be of general value to clinicians,...

In his preface, the author states that this book is offered as a sourcebook. It is clearly intended for students and contains several features that should be attractive to them. The title of the book aptly describes the author's primary emphasis: lucid, ...

Essential hypertension, a major contributor to cardiovascular disease, affects as many as 60 million Americans. Nearly 100 antihypertensive drugs are available for the treatment of this condition, and new agents continue to be released. The goal of this ...

This book was written specifically for cardiovascular echocardiographic technologists. It also includes much material that would be useful to physician trainees in cardiology who need to learn the basics of ultrasonography and cardiac imaging; cardiac ...

The receipt of these books is acknowledged, and this listing must be regarded as sufficient return for the courtesy of the sender. Books that appear to be of particular interest will be reviewed as space permits.

Addresses of most overseas publishers are ...

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CALL FOR ENTRIES

The American Association of Critical-Care Nurses is soliciting ...

Thin Stage I Primary Cutaneous Malignant Melanoma: Comparison of Excision with Margins of 1 or 3 cm (May 5, 1988; 318:1159–62). On page 1161, in the left-hand column, fourth line, the mean thickness of melanomas in patients who underwent wide excision ...