THE high prevalence of bone fractures among women with osteoporosis makes prevention of this disease important. Bone densitometry makes it possible to quantify the risk of fracture in both the appendicular and the axial skeleton.^{1 2 3 4} The forearm is a ...

CARDIOVASCULAR disease is the leading cause of death among women in industrialized countries. Postmenopausal women who take estrogens generally have lower rates of cardiovascular disease than women of a similar age who do not,^{1 2 3} possibly because ...

BACILLE Calmette–Guérin (BCG) immunotherapy has recently been approved by the Food and Drug Administration for the treatment of carcinoma in situ of the bladder. Randomized, prospective, controlled trials have confirmed that treatment with BCG is superior ...

THE beneficial effect of a blood transfusion before transplantation on allograft survival has been well documented both in humans and in animal models.^{1 , 2} However, the mechanisms involved are still largely unknown. Recently, as a result of improved ...

EXCESSIVE ingestion of licorice may result in sodium and water retention, hypertension, hypokalemia, and suppression of the renin-aldosterone system.^{1 , 2} It was thought for years that licorice produced these effects through the binding of its active ...

Fibersigmoidoscopy

Although many indications for fibersigmoidoscopy are listed in Table 2, the majority of procedures are surveys for cancer in asymptomatic persons. Although the American Cancer Society¹²³ and the National Cancer Institute¹²⁴ endorse the ...

Presentation of Case

A 27-year-old man with the acquired immunodeficiency syndrome (AIDS) was admitted to the hospital because of a cough, fever, and an abnormal radiograph of the chest.

The patient was well until 8 1/2 months earlier, when he was first ...

IN 1945 Ray Owen reported a remarkable finding.¹ He had examined the blood groups of freemartin cattle, which are fraternal twins born from a common placenta, and concluded that their blood groups could only be explained if hematopoietic cells had been ...

LICORICE extract from the root of Glycyrrhiza glabra is one of the sweetest substances known and has long been used in Chinese medicines. After the discovery of its value in the treatment of peptic ulcer, it was not long before its adverse effects on salt ...

THE ability to transplant solid organs successfully is one of the most miraculous accomplishments of modern medicine. For a patient with end-stage renal disease, a renal transplant offers the best chance of rehabilitation and long-term survival. Renal ...

AS of April 1991, there were 22,842 people in the United States on the waiting lists for organs for transplantation.¹ The list is getting longer each year. Many patients die waiting for organs. Others must be maintained on dialysis for want of a ...

To the Editor: Lee et al. (May 2 issue)¹ are to be congratulated on their excellent paper, which shows the value of clinical decision making. However, there are complementary strategies for the rapid confirmation or exclusion of acute myocardial ...

To the Editor: The publication in the Journal of our report "Human Immunodeficiency Virus Type 1 Infection in Homosexual Men Who Remain Seronegative for Prolonged Periods" (June 1, 1989, issue) generated concern both in the scientific community and among ...

To the Editor: Many diseases with a suspected autoimmune cause have been associated with alleles of the HLA Class II region. A few of the HLA-associated diseases have been related to specific amino acids or epitopes of the domains of the Class II ...

To the Editor: Spinal headache results from the continued leakage of cerebrospinal fluid through a rent in the dura and arachnoid membranes.^{1 2 3 4 5 6 7 8} An autologous epidural blood patch relieves the headache by stopping the leakage and is effective ...

To the Editor: Steenland et al. at the National Institute for Occupational Safety and Health (NIOSH) reported on a study of workers exposed to ethylene oxide (May 16 issue).¹ My colleagues and I have conducted a parallel but independent study based on ...

To the Editor:... Even if a person diligently fills out a detailed document specifying advance directives for medical care, many of the choices made may be very poor ones and probably should not be honored. In the study by Danis et al. (March 28 issue),¹ ...

To the Editor: A growing number of adverse effects of the use of video and hand-held electronic games are being reported, including wrist pain,¹ tenosynovitis,² peripheral neuropathy,³ and seizures.^{4 , 5} Even fecal incontinence has been attributed to ...

This book argues that American physicians have been duped by greedy drug companies and a misguided research establishment into believing that high levels of cholesterol are dangerous and require treatment. The American public is now suffering the ...

In "The Ph.D. Octopus," an essay published in 1903, William James argued that it was the quality of the person — not the doctoral degree — that was more important in hiring a new college professor. Although initials after the name did not necessarily ...

For this ambitious study of the content and quality of primary pediatric care, conducted in the 1970s, Duff and colleagues recruited 436 families and 61 pediatricians and observed 1221 office visits. They examined fee-for-service solo practices and ...

Professor Brandt has set himself two important goals: the description of a wide range of clinical disorders in which vertigo is a feature, and the presentation of new physiologic information concerning the pathogenic mechanisms of vertigo. Because vertigo ...

The 12 chapters of this book review the somatoform disorders, a group of conditions with somatic symptoms for which no organic cause can be demonstrated and that are thought to be due to psychological or "functional" disturbances. The chapters cover ...

It has been estimated that there are 1.1 million to 1.3 million intravenous drug abusers in the United States. Many are considered outcasts from society. They are often poor and unemployed, they usually lack health insurance, they may resort to criminal ...

The editors of this book, now in its second edition, have performed a tour de force in organizing an enormous amount of information on sexually transmitted diseases, ranging from molecular biology through clinical considerations to social and legal ...

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6TH WORLD CONFERENCE ON LUNG CANCER

The conference will meet in Melbourne, ...