IN spite of recent improvements in the medical and surgical treatment of patients hospitalized with acute myocardial infarction,^{1 2 3 4 5 6 7} cardiogenic shock and other manifestations of left ventricular failure continue to occur. The development of ...

OPIOID analgesia has been associated with the activation of opioid receptors in the central nervous system. Recently, however, we and others have demonstrated that exogenous¹–³ as well as endogenous^{4 , 5} opioid agonists have peripheral antinociceptive ...

GASTRIC carcinoma is estimated to be the world's second most common cancer.¹ Although the dramatic decline in the incidence of gastric carcinoma in the United States and Western Europe over the past 50 years has led some to proclaim an "unplanned triumph,"...

GASTRIC carcinoma is one of the most frequently diagnosed malignant diseases worldwide,¹ and in the United States it was the leading cause of death due to cancer in 1930.² Since then, the mortality rate for gastric carcinoma has fallen steadily in the ...

ASPIRIN has been shown to reduce the incidence of death significantly in patients presenting with unstable coronary vascular disease.^{1 2 3} The clinical benefit of aspirin is thought to derive from inhibition of thromboxane A₂ production.⁴ Thromboxane A₂ ...

THE sickle cell trait is generally considered to be benign, because the presence of hemoglobin A in a concentration of more than 50 percent in the red cells of persons heterozygotic for hemoglobin A and hemoglobin S (hemoglobin A/S) prevents the ...

GASTROINTESTINAL endoscopy has grown over the past 25 years from a technical curiosity mastered by a handful of physicians to a major component of our health care system. The volume and total cost of gastrointestinal endoscopic procedures have recently ...

Presentation of Case

A 63-year-old woman was admitted to the hospital because of a question of a tumor of the right lung.

The patient was in stable health until one year earlier, when a dry cough developed. An x-ray film of the chest, obtained elsewhere, ...

In this issue of the Journal, Goldberg et al. have estimated the incidence of cardiogenic shock complicating acute myocardial infarction.¹ Their study includes more than 4000 patients cared for over a 14-year period at hospitals in the Worcester, ...

It is generally accepted that systemically administered opiates produce analgesia through an action in the central nervous system. Indeed, mu, delta, and appa opiate receptors and receptor-selective opioid peptides, although widely distributed in the ...

Two articles in this issue of the Journal reach the conclusion that past infection with Helicobacter pylori increases considerably the risk of gastric carcinoma.^{1 , 2} One reaction to this interesting finding could be a desire to eradicate H. pylori as a ...

To the Editor: I am president of the American Academy of Otolaryngic Allergy (AAOA). We are an American Medical Association-delegated society of more than 1800 members and the second largest subspecialty society of otolaryngology. We are also the second ...

To the Editor: Transmission of human immunodeficiency virus type 1 (HIV-1) is one of the most serious infectious complications of transfusion or transplantation. Soon after this virus was identified as the agent in the acquired immunodeficiency syndrome,^...

To the Editor: Steinberg recently reported his experience with the use of recombinant human erythropoietin for the anemia of renal failure in sickle cell disease (May 9 issue).¹ In the two patients whom he describes, the diagnosis of anemia of renal ...

To the Editor: In his review on erythropoietin (May 9 issue),¹ Erslev states that it is still an unanswered question whether athletes competing in exhausting long-distance events would benefit from a moderate increase in the hematocrit and red-cell mass. ...

To the Editor: In his editorial (May 9 issue)¹ Doolittle acknowledges the demonstrated clinical value of erythropoietin in the treatment of renal disease and its potential value in the treatment of other conditions. Erythropoietin has recently been made ...

To the Editor: Cutaneous herpes zoster infection is a problem frequently encountered in clinical practice. Therapy with a high dose of oral acyclovir (800 mg five times per day for 10 days) has been reported to shorten the duration of viral shedding, ...

To the Editor: A clinically important and hitherto unreported drug interaction between verapamil and phenytoin has come to our notice in the case of a patient with hypertrophic obstructive cardiomyopathy. It resulted in an almost complete lack of ...

The small dark girl makes her way slowly up the long subway stairs because something from her past is shooting through her, like a flame singeing her lashes, her loveliest feature; something about incurable skin, pregnancy at fourteen and an abortion at ...

Efficient and undistorted communication of the findings of medical research is fundamentally important to physicians, researchers, and ultimately the public. Many investigators have assumed that the popular media are an irrelevant and perhaps unseemly ...

Trauma is responsible for an enormous drain on medical resources, for lost lives, and for lost productivity. Important improvements in the care of patients with trauma have occurred over the past several decades, often as a result of military experience. ...

Rosen and Barkin have previously edited two excellent books, Emergency Pediatrics (3rd ed. St. Louis: C.V. Mosby, 1990; $49) and Emergency Medicine: Concepts and clinical practice (St. Louis: C.V. Mosby, 1983; $190). Now they have distilled their efforts ...

This fine addition to the textbooks on gross anatomy available for medical and dental students is intended to be both a textbook and a photographic atlas focusing on dissection of the human cadaver. It gives the student a realistic view of the gross ...

Graft-versus-host disease (GVHD) remains one of the important complications associated with allogeneic bone marrow transplantation and is a major problem, especially in older patients and patients who receive bone marrow from an unrelated donor or from an ...

Practitioners in the field of cytology have waited a long time for a book like this. Not since the last edition of Koss' Diagnostic Cytology and Its Histopathologic Bases (3rd ed. Philadelphia: J.B. Lippincott, 1979) has there been a book of such scope ...

This is a fine collection of photographs, micrographs, radiographs, and other images from modern cardiology. It is comprehensive, current, and organized into clinically relevant chapters on topics such as ischemic, valvular, myocardial, and congenital ...

The receipt of these books is acknowledged, and this listing must be regarded as sufficient return for the courtesy of the sender. Books that appear to be of particular interest will be reviewed as space permits.

Addresses of most overseas publishers ...

Notices submitted for publication should contain a mailing address and phone number of a contact person or department. We regret we are unable to publish all Notices received.

CALL FOR ABSTRACTS

Abstracts are now being accepted for the "158th National ...

Exercise and Decreased Risk of NIDDM (July 18, 1991;325:196–8). On page 197, right-hand column, line 20, "24 percent" should have read "41 percent." We regret the error.