CYTOMEGALOVIRUS (CMV)-associated interstitial pneumonia is the most common infectious cause of death after allogeneic bone marrow transplantation and thus is an important factor in limiting the success of this procedure.^{1 2 3 4} In a series of 525 ...

IT is well known that excessive ingestion of magnesium causes diarrhea. However, such diarrhea is not easily recognized because no diagnostic criteria for magnesium-induced diarrhea have been established. Although previous investigators have suggested ...

PLACEBO-controlled trials in adults have demonstrated that zidovudine (formerly known as azi-dothymidine, or AZT) is effective for the treatment of human immunodeficiency virus (HIV) disease, including asymptomatic infection.^{1 2 3 4 5 6} Phase I studies in ...

INVASIVE candidiasis is difficult to diagnose and is the cause of substantial morbidity and mortality in patients with cancer.^{1 2 3 4 5} The current approach to the diagnosis of invasive candidiasis consists of clinical suspicion and the use of blood ...

A RECENT study showed that kidneys available to more than 100 centers had an extremely high rate of graft survival if the donors and recipients were matched for two antigens at the HLA-A locus, two at the HLA-B locus, and two at the HLA-DR locus (a six-...

THROUGHOUT the 1980s, both the private sector and the federal government energetically attempted to contain the continuing increase in the costs of hospital care. A key part of their strategy has been to eliminate unnecessary hospital days and to shift as ...

A GRAM-NEGATIVE, microaerophilic curved bacillus found in gastric-biopsy specimens from patients with histologie gastritis was successfully cultured in Perth, Australia, in 1982 and was soon named Campylobacter pylori ¹ (a name later changed to ...

Presentation of Case

A 48-year-old man was admitted to the hospital because of chest pain, dysphagia, fever, and a subcarinal mass.

The patient was in good health until six weeks earlier, when dysphagia developed while he was swallowing a piece of hard ...

TRANSPLANTATION, of both bone marrow and solid organs, must be regarded as one of the great success stories of 20th-century biomedical science. At the same time, it must be recognized that the manipulations required to achieve long-term graft function ...

MAGNESIUM ingestion, usually in the form of laxatives or antacids, can produce diarrhea. Patients who go to tertiary referral centers for evaluation of chronic diarrhea include those who abuse laxatives.¹ Among them are patients who surreptitiously ingest ...

THE evolution of fungi of the genus candida from infrequent pathogens to among the most common agents of nosocomial infection has been both dynamic and interesting. The story of their emergence began in the early 1960s with events remarkably similar to ...

To the Editor: The risk of human immunodeficiency virus (HIV) infection after an incident with a needle contaminated with infected blood has been estimated to be 0.47 percent.¹ After such injuries, zidovudine is usually prescribed to reduce the risks of ...

To the Editor: Concerning the Special Article by Gayle et al. (Nov. 29 issue)* on the prevalence of HIV among university students: Did the students know they were being tested for the HIV antibody? Did each give written informed consent? Were the 30 who ...

To the Editor: As Mclntosh stated in his editorial on congenital syphilis (Nov. 8 issue),¹ almost every case is preventable. I reviewed all reported cases of congenital syphilis in Los Angeles County in 1987, 1988, and 1989. Of the more than 1000 ...

To the Editor: Martin et al. (Oct. 25 issue)¹ emphasized the importance of verotoxigenic Escherichia coli as an etiologic agent in the hemolytic uremic syndrome. We have also studied E. coli O157:H7 infections with the purpose of defining risk factors ...

To the Editor: Respiratory syncytial virus (RSV) infection is the most frequent cause of acute lower respiratory tract disease in infants,¹ and pulmonary hypertension is the one condition particularly associated with life-threatening RSV infection during ...

To the Editor: Inferences drawn from comparative analyses of health care in the United States and Canada have been repetitively debated in the Journal. ^{1 2 3} Enthusiasts of the Canadian system aver that curtailing administrative paperwork and truncating ...

To the Editor: The carefully conducted study by Schoenfield et al. (Nov. 1 issue)¹ demonstrates that adjuvant bile acid therapy after shock-wave lithotripsy of gallbladder stones enhances the disappearance of fragments significantly. However, even in ...

These two books will interest those who consider the problems of human immunodeficiency virus (HIV) infection in social terms. Both are based on historical views of the acquired immunodeficiency syndrome (AIDS). One, Action on AIDS, presents one country ...

Different students have different styles of learning. In the area of medical microbiology, these diverse needs are met by a variety of quality textbooks ranging from short reviews to midsize and comprehensive books.

Essentials of Medical Microbiology is ...

Many physicians receive only rudimentary training in dermatology, yet they are confronted daily by a multitude of skin disorders. Timely diagnosis and treatment or referral influence a patient's morbidity greatly. In this second edition, subtitled "A ...

I have been leading house officers through general dermatology textbooks for my entire professional career, and I have a 6-foot shelf filled with these books. Not one of them has given me as much pleasure and enthusiasm for reading as has this book. It is ...

Over the past decade, geriatrics has matured as an academic discipline recognized to be an essential specialty of clinical practice. Sophisticated approaches to care are emerging, as well as advances in the specific management of geriatric conditions. The ...

The editors' aim is "to produce a multi-author text which is authoritative and up-to-date, and which reflects the best British traditions by combining applied science with good clinical practice." They have succeeded admirably. I would add that at least ...

Of what use is a book devoted totally to consultative internal medicine? Why should it be on the shelf of the average internist, who will already have one or two general medical textbooks? Having gone from cover to cover of this readable and concise book, ...

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