CARCINOMA of the rectum is one of the more common malignant diseases in this country, estimated to afflict some 45,500 persons during 1991.¹ It has certainly been one of the most frustrating of therapeutic challenges. Recent national studies have shown 5-...

SCOMBROID-fish poisoning (scombrotoxism) refers to the clinical syndrome that results from the ingestion of spoiled fish, usually of the families Scombridae and Scomberesocidae. This includes tuna, mackerel, skipjack, and bonito.¹ However, nonscombroid ...

HYPOCALCEMIA and hypomagnesemia are frequently encountered in heavy users of alcohol.^{1 2 3 4 5} These changes have been ascribed to concomitant hypoalbuminemia,³ poor nutrition, and increased urinary and intestinal loss of calcium and magnesium.^{6 , 7} ...

CONCERN about the potential reproductive effects of using video display terminals (VDTs) was first raised in 1980, when adverse pregnancy outcomes among several clusters of women who used VDTs were reported.^{1 2 3 4 5} Most subsequent epidemiologic analyses ...

SEVERAL studies have demonstrated insulin resistance in patients with essential hypertension^{1 2 3 4} and an inverse relation between blood pressure and insulin-mediated glucose disposal.^{1 , 2} Thus, it has been postulated that the compensatory ...

DESPITE the well-publicized adverse health effects of tobacco and the declining prevalence of smoking in the United States, slightly more than one in four adults continue to smoke cigarettes.¹ Some smokers may be reluctant to stop smoking because the ...

THE introduction of chlorpromazine in 1952 marked a turning point in the treatment of schizophrenia and other psychotic disorders.¹ Until then, the treatment of these illnesses had met with little success, and many patients with psychosis were held in ...

Presentation of Case

A 65-year-old man was admitted to the hospital because of a question of a lung abscess.

There was a 100—pack-year history of cigarette smoking, with the development of symptoms of chronic obstructive pulmonary disease. The patient was ...

Even the most skeptical observer should be impressed by the rapidity of scientific advances in our management of colorectal cancer, a disease that until recently consumed substantial research efforts that provided no direct benefit to the patient. Now, ...

Despite dramatic advances in food sanitation during the 20th century, acute food-borne disease caused by infectious agents and chemical toxins remains an important public health problem. From 6 to 81 million cases of such disease are estimated to occur ...

More than 1000 years ago, Native Americans were using tobacco, and they were probably aware of its appetite-suppressing and energy-instilling actions.¹ Although scientific papers reporting that the use of tobacco lowered body weight began to appear more ...

To the Editor: We believe that Nadel and his colleagues (Aug. 30 issue)¹ are incorrect in suggesting that there is no need for amniocentesis in patients with elevated maternal serum alpha-fetoprotein levels and a normal ultrasonographic examination. ...

To the Editor: Rearrangement of the variable (diversity) and joining gene segments of the immunoglobulin and T-cell–receptor genes generates unique DNA sequences at the junctional region of these gene segments. This junctional region is different in each ...

To the Editor: The report by Young et al. (April 12 issue)¹ of a prospective, randomized trial in which surgery alone was compared with surgery plus melphalan in patients with well-differentiated or moderately well differentiated ovarian cancer confined ...

To the Editor: Chapman et al. (Oct. 18 issue)* suggest that the renin–angiotensin–aldosterone system is stimulated significantly more in hypertensive patients with polycystic kidney disease than in comparable patients with essential hypertension, and ...

To the Editor: The report of two diabetic patients with painful peripheral neuropathy who were successfully treated with topical capsaicin (Aug. 17, 1989, issue)¹ will have been encouraging to many diabetologists faced with this difficult problem, which ...

To the Editor: Sustained elevation of levels of atrial natriuretic factor in plasma has been reported after human orthotopic heart transplantation despite normal graft function,^{1 , 2} but the exact mechanisms of the increase are still unknown. Studies of ...

To the Editor: Ticks frequently cause human disease by transmitting infectious agents (protozoa, rickettsia, bacteria, and viruses) or by releasing toxins during feeding that are responsible for reactions ranging from local irritation to paralysis.¹ ...

To the Editor:... During the recruiting season for the 1990 National Resident Matching Program, we became aware that some internal medicine programs were offering "perks" to prospective applicants that in our opinion denigrate and blur the academic ...

It is a peculiar phenomenon in psychiatry that there are many books about specialty areas, theoretical frameworks, and treatments, but a book such as this one, devoted entirely to one major disorder, is quite rare. Indeed, the last comprehensive book ...

The international epidemic of human immunodeficiency virus (HIV) infection and the acquired immunodeficiency syndrome (AIDS) among drug injectors has led many countries to consider opening or expanding programs of methadone maintenance treatment. In the ...

Persons with chronic mental illness, like those with mental retardation or dementing illnesses, must rely on their families for protection, support, and advocacy. The families confront an incomplete and poorly coordinated system of long-term care and thus ...

This work is a compilation of manuscripts from a symposium on post-traumatic stress disorder. The chapters lack integration, and the editors did not include a summary of conclusions or attempt to resolve contradictions. One can best use this book by ...

This scholarly book provides a thorough, critical account of the extensive recent work on the relations between personality and disease. It acknowledges the extraordinary difficulties that beset the establishment of such relations: the various types and ...

This book is intended for both physicians and laypersons. It provides an excellent blending of medical, legal, and psychosocial information with sensible clinical applications. While many readers will already be aware of the rampant problem of child abuse ...

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CANCERS OF THE SKIN

The congress will be held in New York, April 18–20, ...