Bacteria from patients in some countries are more likely to be resistant to antimicrobial agents than comparable isolates from patients in other countries.^{1 2 3} Comparative surveys, however, have included strains that were epidemic in some regions or ...

Oral lichen planus is a relatively common disorder affecting up to 2 percent of the general population.¹ Any oral mucosal site may be involved, and there are usually multiple areas of involvement. Although reticular and papular lesions occur most ...

Chronic hepatitis B is a serious and often progressive liver disorder for which there is no accepted therapy. Several small clinical trials have suggested that interferon may be helpful in the management of this condition, but most of these studies were ...

Coagulase-negative staphylococci have become the most common blood-culture isolates in neonatal intensive care units.^{1 2 3 4 5 6 7 8 9 10} Many investigators have suggested that the use of intravascular catheters, particularly central venous catheters, is ...

The human placenta is impermeable to free insulin, so the insulin in the fetus and in the amniotic fluid is presumed to be entirely fetal in origin.^{1 , 2} Furthermore, the inability to detect Radio-labeled insulin in the cord serum of neonates born to ...

Hypersecretion of growth hormone during childhood causes excessive linear growth and gigantism. Acromegaly results from the hypersecretion of growth hormone after epiphyseal fusion. Children with gigantism may also have acromegalic physical ...

Graft-versus-host disease is commonly observed after allogeneic bone marrow transplantation but rarely recognized after transfusion or solid-organ transplantation.^{1 2 3} Transfusion-associated graft-versus-host disease can occur in immunosuppressed ...

Presentation of Case

A 42-year-old woman was admitted to the hospital because of increasing dyspnea and a cough.

The patient was a native of the Cape Verde Islands and spoke only Portuguese. Three months before admission she came to this country to visit ...

Bacterial resistance to antibiotics, initially recognized in hospitals, was subsequently identified in community-acquired infections as well. Today it is a major obstacle to the treatment of infectious diseases, leading not only to treatment failures but ...

Chronic hepatitis B is said to affect at least 5 percent of the world's population and to be the chief cause of cirrhosis and hepatocellular carcinoma.¹ The World Health Organization lists hepatitis B as the ninth major cause of death worldwide, close ...

Coagulase-negative staphylococci are constituents of the normal microflora of the skin, but they are also capable of harming patients who have benefited from medical innovations such as cerebrospinal fluid shunts, intravascular catheters, peritoneal ...

Macrosomia is a characteristic feature of diabetic pregnancy. The infants of mothers with diabetes mellitus (especially those with poorly controlled insulin-dependent diabetes or gestational diabetes) have increased body fat and selective organomegaly, ...

DEATHS

Bartol — George Murillo Bartol, M.D., of Milton, died on June 13 at the age of 80.

Dr. Bartol received his degree from the University of Pennsylvania School of Medicine in 1939. He was a member of the American Medical Association.

Broderick — ...

To the Editor: In his editorial (March 1 issue),* Dr. Relman touches on a key and often ignored issue in the medical-malpractice tangle when he says "incompetent medical practice does exist and is of major concern to the public." The assignment of ...

To the Editor: Electronic fetal-heart-rate monitoring is a technique that simply presents a continuous record of the pulse rate as influenced by uterine contractions. It is imperative that professionals understand the limitations of interpreting a simple ...

To the Editor: The article by Johnson et al. (March 8 issue)* on the inhibition by immunoglobulins of glucose transport into islet cells suggests another possible mechanism for the destruction of islet cells — namely, intracellular hypoglycemia. If beta-...

To the Editor: In their recent study (Jan. 25 issue),¹ Ostlund and coworkers examined a cohort of 146 healthy subjects 60 to 70 years old to determine the main clinical and laboratory characteristics related to HDL₂ subfraction levels in plasma. They ...

To the Editor: We were struck by the report of Pipeleers-Marichal et al. (March 15 issue)¹ that the gastrinomas in eight patients with multiple endocrine neoplasia type 1 (MEN-1) and the Zollinger-Ellison syndrome were located in the proximal duodenum ...

To the Editor: The results of a randomized trial of adjuvant chemotherapy for pathologically proved, Stage II nonseminomatous testicular cancer were published in 1987.¹ Among 97 patients assigned to receive chemotherapy, only 1 had a recurrence despite ...

To the Editor: As an endocrinologist long interested in hair growth I have recently been intrigued by an observation in orthopedic patients. After a tibia-fibia fracture, my wife noted the growth of lush, dark terminal hair on the skin over the area of ...

Table for one? I thought, eyes fixed On the candles On the ceiling.

My, but this wine Takes my breath away And blurs my eyes And ears, and tongue.

Though in haze, I see That this is a feast! A feast of myself! Dressing and all.

Take this away, Waiter! Can'...

In this era of routine echocardiograms and ultra-fast cardiac CT scanning, cardiac auscultation is in danger of becoming a lost art. Fortunately, Proctor Harvey remains dedicated to the idea that the careful auscultation of the heart is important and ...

There has been an increasing need for a new, comprehensive textbook dealing with the electrocardiography of cardiac arrhythmias. This new work provides an excellent resource for cardiologists, internists, students, residents, and critical care workers who ...

Here is a comprehensive textbook that reviews all aspects of electrical treatment for cardiac arrhythmias, The material is presented in four sections: pathophysiology, cardiac pacing, antitachycardia devices, and ablation therapy.

The section on pacing ...

"A man's reach should exceed his grasp," wrote Browning, and so it is with this book which, in the words of its editor, "is designed to draw together studies of human leukemia, both clinical and biologic, in such a manner that it may serve as a useful ...

The role of the immune system as a feature of host defense against cancer is only partly understood. A broad spectrum of responses has been described. On the one hand, there are a variety of cellular and humoral reactions deleterious to tumor growth. On ...

At a time when just about every scientific publishing firm is trying to introduce its own textbooks on a variety of medical topics, books that have enjoyed a good long-term reputation are rarities. Andrews' Diseases of the Skin is such a work. The first ...

It was a pleasure to read this erudite compilation. The author is a professor of dermatology and cutaneous surgery and of pathology at the University of Miami School of Medicine, where he is the director of dermatopathology. Penneys makes splendid use of ...

The receipt of these books is acknowledged, and this listing must be regarded as sufficient return for the courtesy of the sender. Books that appear to be of particular interest will be reviewed as space permits.

Addresses of most overseas publishers ...

Notices submitted for publication should contain a mailing address and phone number of a contact person or department. We regret we are unable to publish all Notices received.

EATING DISORDERS

The course will be offered in London, Sept. 27 and 28.

...

These guidelines are in accordance with the "Uniform Requirements for Manuscripts Submitted to Biomedical Journals." (The complete document appears in the February 6, 1988, issue of the British Medical Journal and the February 1988 issue of the Annals of ...