OF the 25 million patients who undergo noncardiac surgery in the United States each year, approximately 3 million have or are at risk of having coronary artery disease.¹ Despite recent advances in the diagnosis and therapy of coronary artery disease, ...

IT has long been assumed that sperm must pass through a certain length of the epididymis to mature, gain progressive motility, and become capable of fertilization.^{1 2 3} In some animal studies, surgical ligation of the epididymis has allowed sperm to ...

BRONCHOPULMONARY dysplasia was first described in 1967 as a syndrome of chronic lung disease in prematurely born infants who had been treated for respiratory distress syndrome with supplemental oxygen and mechanical ventilation.¹ The clinical diagnosis of ...

HEMOPHILIA A is an X-linked recessive genetic disorder affecting approximately 1 in 10,000 males that is due to a defective or deficient factor VIII molecule, resulting in a hemorrhagic tendency.¹ In its most severe form, hemophilia A is a life-...

ALTHOUGH enterococci are normal inhabitants of the gastrointestinal and female genital tracts, they are now recognized as formidable pathogens in hospitalized patients.^{1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17} Many patients become infected with their own ...

BONE marrow from unrelated donors is increasingly being transplanted for the treatment of patients with leukemia, aplastic anemia, and lethal congenital disorders of hematopoiesis and immunologic function. National and international registries of HLA-...

CONGENITAL adrenal hyperplasia due to 21-hydroxylase deficiency is a relatively common genetic disorder. On the basis of worldwide screening programs, the incidence has been calculated to be approximately 1 per 14,000 births.¹ Despite impressive advances ...

Presentation of Case

A 31-year-old woman was admitted to the hospital because of headache, altered mental status, and dysarthria.

The patient was well until seven years earlier, when squamous-cell carcinoma of the cervix, Stage IB, was found. A radical ...

The development of techniques for the mechanical ventilation of patients with respiratory failure must count as one of the major advances in medical therapy in the past 40 years. During the 1960s, knowledge about how the lung works was translated into ...

The epidemic on an infant–toddler surgical ward that Rhinehart et al.¹ describe in this issue of the Journal has some of the classic characteristics of epidemics in adults and others that are typically pediatric. The antibiotic-resistant strain of ...

DEATHS

Dalrymple — Leolia A. Dalrymple, M.D., of Rockport, died on Feb. 1. He was 95.

Dr. Dalrymple graduated from the University of Toronto Faculty of Medicine in 1925. He was a member of the American Medical Association and the American Psychoanalytic ...

To the Editor: The Sounding Board article by McClung and Kamer (July 26 issue)¹ on the implications of New York's do-not-resuscitate (DNR) law underestimates the mischief wrought by this misguided piece of legislation in New York hospitals. The ...

To the Editor: In their important study Smith et al. (July 19 issue)¹ demonstrated a significant reduction in the risk of death, reinfarction, and cerebrovascular accident in patients who survived a myocardial infarction and received long-term warfarin ...

To the Editor: Samuels et al. (July 26 issue)* conclude that "the absence of a history of immune thrombocytopenic purpura or the presence of negative results on circulating-antibody testing in pregnant women indicates a minimal risk of severe neonatal ...

To the Editor: The article on seroprevalence rates of human immunodeficiency virus type 1 (HIV-1) at sentinel hospitals by St. Louis et al. (July 26 issue)* raised, but did not address, important ethical issues.

The authors described a three-stage ...

To the Editor: The epidemiologic picture of the acquired immunodeficiency syndrome (AIDS) and human immunodeficiency virus (HIV) infection in the Soviet Union is incomplete, partly because of official denial of many health problems carrying a negative ...

To the Editor: Renal-artery thrombosis occurs in 0.1 to 2 percent of cadaveric kidney transplants and is associated with hypotension, rough handling of the organ, the administration of antilymphocyte globulin and early postoperative treatment with ...

To the Editor: A 21-year-old nonsmoking woman with a history of asthma was seen for wheezing and dyspnea of six weeks' duration; these symptoms had been treated with adjusted doses of theophylline preparations, inhaled beta-agonists, and inhaled ...

To the Editor: Aspirin is a well-known cause of tinnitus. Although disturbing, this side effect usually disappears when the dose is decreased. We wish to describe a patient in whom even a very low dose of aspirin caused tinnitus when administered in an ...

With the Diagnostic and Statistical Manual of Mental Disorders (third edition) (DSM-III), and now with DSM-III, revised (DSM-III-R), modern psychiatry has made efforts to achieve a uniform classification of mental disorders and enhance diagnosis, research,...

This book begins by stating a central problem that medical students face in becoming physicians:

The essence of the complete physician is the ability to integrate excellent medical treatment with compassionate psychological care of the patient. The ...

Of the approximately 3 million Americans who served in Southeast Asia during the Vietnam War, a large number acquired a broad range of symptoms on their return, including drug abuse, violence, and other severe social dysfunctions. They were described in ...

The U.S. government has declared war on the production and use of illicit drugs. The international drug business begins with poor farmers who grow opium poppies in Southeast Asia and the Middle East and with their counterparts in Central and South America ...

As Feierman notes in his concluding chapter of this excellent book, Western industrialized societies have recently granted new freedom and tolerance to various minorities and increased their tolerance of sexual behaviors such as homosexuality. Tolerance ...

In their preface, the editors state an ambitious goal: to integrate the two models that compose the biopsychosocial perspective — the "traditional environmental, interpersonal, and psychological" and the "more recent biological/medical." Acknowledging ...

Surgery

Arthroscopic Surgery. (Management of Complications in Orthopaedics.) Edited by Orrin Howard Sherman and Jeffrey Minkoff. 221 pp., illustrated. Baltimore, Williams and Wilkins, 1990. $49.95.

Back Pain: An international review. Edited by John K. ...

MEDICAL ISSUES/DATA MANAGEMENT

The conference will take place in Tucson, Ariz., Jan. 13–16.

Contact American Managed Care and Review Assoc., 1227 25th St., NW, Suite 610, Washington, DC 20037; or call (202) 728–0506.

NEW YORK UNIVERSITY MEDICAL CENTER

The ...