HYPERACTIVITY is a disorder of unknown cause that affects 2 to 4 percent of school-age children.^{1 , 2} Despite extensive efforts, researchers have been unable to demonstrate consistent neurobiologic differences between hyperactive children and normal ...

LARON and colleagues in Israel were the first to describe short stature with the characteristic features of isolated growth hormone deficiency but with elevated serum levels of growth hormone in children and normal-to-slightly-increased levels in adults.¹ ...

ORAL contraceptive agents can induce substantial metabolic changes that resemble those seen in persons at increased risk for premature coronary heart disease.¹ These changes include raised serum triglyceride and low-density lipoprotein (LDL) cholesterol ...

THE importance of Haemophilus influenzae type b bacteria as the primary cause of bacteremic infections in children has been realized only recently. In the United States, 85 percent of the approximately 20,000 cases of invasive H. influenzae type b ...

NATIVE American children, including Alaskan Eskimos,^{1 , 2} Canadian Inuits,³ Navajos,^{4 , 5} and Apaches,⁶ are at greater risk of invasive bacterial infections than white children. Bacteremic infections due to Haemophilus influenzae type b and Streptococcus ...

INVASIVE Haemophilus influenzae type b disease —meningitis, bacteremia, septic arthritis, pneumonia, cellulitis, and epiglottitis — remains a leading worldwide cause of morbidity and mortality among young children. In the United States there are at least ...

THE finding of an adrenal mass in the course of abdominal computerized tomography (CT) performed for other reasons poses an increasingly common clinical problem. The prevalence of such incidentally recognized masses ranges from 0.6 to 1.3 percent.^{1 2 3} An ...

Presentation of Case

A 63-year-old woman was admitted to the hospital because of fever, a bullous lesion on the right buttock, and subcutaneous emphysema.

The patient was well until one month earlier, when there was the onset of intermittent constipation ...

THE findings described by Zametkin and his co-workers in this issue of the Journal ¹ represent a clear advance in our understanding of the biologic antecedents of hyperactivity, or attention deficit–hyperactivity disorder (ADHD). The authors studied ...

Landsteiner¹ and then Avery and Goebel² discovered how to increase the ability of saccharides (haptens) to elicit antibodies by chemically binding them to proteins to form conjugates. About three quarters of a century later, these discoveries have ...

Cardiologic practices are an important contributor to the cost of medical care today. Combining the high prevalence of cardiovascular disease with medical and surgical interventions that involve expensive forms of technology creates high costs. There has ...

DEATHS

Aney — Paul Melvin Aney, M.D., of Hubbardston, died on July 28 at the age of 58.

Dr. Aney received his degree from the University of Illinois College of Medicine in 1960. He was a member of the American Medical Association, the American Academy of ...

To the Editor: Vichinsky et al. (June 7 issue)¹ conclude that alloimmunization following blood transfusion occurs more frequently in black patients with sickle cell disease. They then recommend matching the race of blood donors with that of recipients to ...

To the Editor: Dr. Gelfand stated in his editorial (June 14 issue)¹ that only 10 to 20 percent of patients with severe combined immunodeficiency (SCID) have lymphopenia. This is contrary to our experience and that of others.^{2 , 3} The absolute lymphocyte ...

To the Editor: Well-controlled studies of various physical-therapy treatments are essential to establish their clinical effectiveness. Deyo and colleagues (June 7 issue)¹ have prudently focused their examination on transcutaneous electrical nerve ...

To the Editor: Insulin-like growth factor I (IGF-I) is a homologue of proinsulin, and its intravenous administration has been studied in normal subjects.¹ It possesses approximately 6 percent of the hypoglycemic effect of insulin, and its cellular ...

To the Editor: In a recent letter to the Journal (June 7 issue),¹ Coren presented data from a study of 2228 university freshmen suggesting that higher maternal age is associated with a greater incidence of left-handedness. Coren concluded that "these ...

To the Editor: Emergency treatment for acute loss of vision due to vascular occlusion includes the surgical methods of paracentesis and iridectomy, mechanical ballottement of the globe, rebreathing of carbon dioxide, anticoagulation therapy, and ...

To the Editor: Fine et al., in their letter of June 7,* point to two incidents at New York Hospital—Cornell Medical Center involving confusion between the acid-pump inhibitor Losec (omeprazole), recently released by Merck Sharp and Dohme, and the widely ...

To the Editor: The common disorder called "tennis elbow" has well-known clinical characteristics including discomfort in the region of the radiohumeral joint, is usually associated with the repeated pronation and supination of the forearm with extension ...

Faced with the expanding volume and increasing complexity of information on the pathogenesis of disease, teachers of pathology are confronted with what at first appears to be a no-win situation: teach only the bare essentials of the discipline and leave ...

This introductory textbook is a distillation of the authors' comprehensive volume, Pathology (1576 pp., illustrated. Philadelphia: J.B. Lippincott, 1988), and is designed for medical students. As in the parent volume, 9 chapters are devoted to general ...

The terms "essential" or "concise" in the title of a book all too often mean "superficial" or "incomplete." That is not the case with this textbook, written mainly by the editors and containing specific contributions by eight other authors. Designed ...

Do we need another textbook on aspiration cytology? Dr. Suen addresses this issue succinctly when he discusses the use of aspiration cytology of the breast. Mastectomy is performed without an intervening frozen section when Dr. Suen makes a cytopathologic ...

This book is intended as a practical textbook and atlas for service-oriented pathologists, residents, and cytotechnologists. It is a multi-authored work and includes some distinguished cytologists as contributors. The book contains chapters dealing with ...

The non-Hodgkin's lymphomas constitute a biologically, pathologically, and clinically diverse group of neoplasms of the immune system. Physicians responsible for treating patients with non-Hodgkin's lymphoma often face a wide array of diagnostic tests and ...

Nursing

Assessing the Driving Ability of the Elderly. Edited by Ellen D. Taira, with Marianne Maynard and M. Jeanne Madigan. 215 pp. New York, Haworth Press, 1989. $29.95.

The Cancer Experience: Nursing diagnosis and management. By Doris L. Carnevali and ...

CALL FOR ABSTRACTS

Abstracts are now being accepted for the "3rd Asian Pacific Symposium on Cardiac Rehabilitation," entitled "Cost-Effective Developments in Coronary Artery Disease Management," to take place in Singapore, March 15–17. Deadline for ...

Stereotactic Heavy-Charged-Particle Bragg-Peak Radiation for Intracranial Arteriovenous Malformations (July 12, 1990; 323:96–101). On page 97, in the left-hand column, the first sentence of the second paragraph in the "Methods" section should have read, "...

Leukotrienes and Other Products of the 5-Lipoxygenase Pathway — Biochemistry and Relation to Pathobiology in Human Diseases (September 6, 1990; 323:645–55). On page 648, in the right-hand column, the 12th line of the first paragraph under the heading "...