POSTMENOPAUSAL osteoporosis is a common and costly disease.¹ Approved therapies in the United States include oral estrogen^{2 , 3} and parenteral synthetic salmon calcitonin⁴; sodium fluoride^{1 , 5 6 7} and intranasal calcitonin⁸ have been used experimentally. ...

EXTENSIVE epidemiologic studies^{1 2 3 4} have shown a clear association between chronic infection with hepatitis B virus (HBV) and primary liver cancer. The evidence for this association includes the geographic congruence between areas with a high incidence ...

ERYTHROCYTOSIS (an elevation in red-cell mass with normal plasma volume) is well known to occur after renal transplantation.^{1 2 3 4 5} This complication is estimated to affect 10 to 15 percent of renal-transplant recipients.³ Various causes have been ...

THE consensus has been that women with hypothyroidism who are taking a maintenance dose of thyroxine rarely require an increase in the dose during pregnancy.^{1 , 2} This view is supported by reports that despite an increase in the serum concentration of ...

IN 1983, Kjellberg et al. presented follow-up on the first 74 patients with arteriovenous malformations of the brain treated with Bragg-peak proton-beam therapy.¹ Since then, stereotactic Bragg-peak radiation with protons or helium ions has been used to ...

MYCOBACTERIUM tuberculosis and Mycobacterium avium–intracellulare are among the common pathogens that infect patients with the acquired immunodeficiency syndrome (AIDS).^{1 2 3} In this report, we describe a patient seropositive for the human ...

THE past decade has seen tremendous growth in the use of echocardiography for the diagnosis and treatment of patients with heart disease. This growth has been due primarily to the development of two-dimensional imaging techniques and the integration of ...

Presentation of Case

A 72-year-old woman was admitted to the hospital because of severe abdominal pain.

The patient was well and active until five days earlier, when there was the onset of severe band-like pain about the level of the umbilicus, without ...

Osteoporosis is an enormous public health problem, causing more than 1.5 million fractures and costing up to $10 billion in the United States each year. The most widely used treatment is calcium supplementation. It is safe and relatively inexpensive. ...

In this issue of the Journal, Mandel and coworkers report that women with primary hypothyroidism who were receiving thyroxine therapy often needed a larger dose of thyroxine when they were pregnant.1 This conclusion was based on the authors' finding of ...

The careful report on radiation treatment of cerebral arteriovenous malformations in this issue of the Journal is timely because of the current high level of interest in focused radiation to treat not only cerebral arteriovenous malformations but also ...

To the Editor: In their intriguing report relating hypokalemia to the development of renal cysts, Torres et al. (Feb. 8 issue)¹ note with surprise a positive correlation of plasma renin activity with the extent of cystic involvement and demonstrate that ...

To the Editor: Diaz et al. (Jan. 11 issue)* found deletions of interferon genes in the leukemic cells of patients with acute lymphoblastic leukemia (ALL), which led them to some questionable propositions. Their paper concludes:

We have shown that ...

To the Editor: Patchell et al. (Feb. 22 issue)¹ report that surgical resection followed by whole-brain radiation therapy for single brain metastasis prolongs overall survival and functional independence and reduces the risk of local recurrence as ...

To the Editor: In regard to the review article of Williams (Feb. 8 issue)¹ concerning periodontal disease, we wish to point out the crucial role of proteolytic enzymes of human cells, most notably interstitial collagenases, in the destruction of ...

To the Editor: Diclofenac (Voltaren) is a recently introduced anti-inflammatory agent that is formulated as an enteric-coated product. We report the development of colonic ulcerations after the initiation of diclofenac therapy in two patients who were ...

To the Editor: Recent legislation directed the Massachusetts Department of Public Health to promulgate regulations establishing a lead-screening schedule for children in the commonwealth, "after consultation with major medical groups." A committee, which ...

To the Editor: When Sloan et al. compared guns, gun laws, and homicide rates in Vancouver and Seattle,¹ the study was denounced by me^{2 , 3} and, among others, two of the leading criminologists on the gun issue — Wright⁴ and Kleck, who said:

The research ...

Armed with the advantage of undivided authorship, Rosse has merged the complementary aspects of hematology, immunology, and transfusion—transplantation biology into a single, harmonious presentation of immunohematology. This is a feat with no strong ...

With a format more reminiscent of a coffee-table art book than a medical textbook, this atlas provides a pictorial approach to most of the topics normally covered in standard textbooks of respiratory medicine. Even though the illustrations provide the ...

Here the editors have gathered a number of contributors to place diagnostic endocrine testing in a context of pathophysiologic mechanisms, with an emphasis on common disorders. The chapters have succeeded variably in reaching this goal, at best a ...

Clinical strategies for the use of prostaglandins and related blocking drugs are the broad subjects of this book. A number of valuable therapeutic methods have been developed in the past decade; the future is promising for the introduction of others.

The ...

Here is the first edition of a comprehensive, well-written textbook of pathology of the gastrointestinal "tubes" (esophagus, stomach, small and large bowel, appendix, and anus). Churchill Livingstone has published Pathology of the Liver (MacSween RNM, ...

Here is a comprehensive multiauthored textbook encompassing the abnormalities of the urinary tract, male genital system, and adrenal glands. Glomerular, renovascular, and tubulointerstitial diseases are excluded, since they are primarily the purview of ...

This well-balanced book combines the basic and practical aspects of both exfoliative cytopathology and fine-needle aspiration biopsy. Part 1 offers a systematic review of the criteria for the identification of normal and malignant cells and includes ...

INTERNATIONAL SOCIETY FOR CARDIOVASCULAR SURGERY

The "20th Latin American Congress of Angiology" will be held in Buenos Aires, Argentina, Sept. 2–6.

Contact Dr. Carlos D. Carbonell, 426 Castroville Rd., San Antonio, TX 78207; or call (512) 433–6452.

NEW ...