BEHçET'S syndrome is a multisystem disorder characterized by recurrent oral and genital ulcers, arthritis, thrombophlebitis, and uveitis. Its cause is presumed to be viral or immunologic,^{1 , 2} and its basic underlying pathologic process is that of a ...

HIP fractures accounted for more than 3 million days of hospital care among Americans 65 years of age or older in 1987.¹ The substantial effect of hip fractures on functional status, mobility, loss of independence, and survival in older people makes the ...

CYSTIC fibrosis is the most common severe autosomal recessive genetic disorder affecting the white population. A review of the clinical, physiologic, and genetic aspects of cystic fibrosis has been published recently.¹ The reported disease frequency in ...

THE identification of more accurate predictors of relapse or survival in patients with cancer of the breast might improve the selection of therapy and guide further investigation into basic biologic questions concerning such tumors.

In 1979, Westley and ...

NEONATAL screening for cystic fibrosis with use of the immunoreactive-trypsin assay on dried blood samples has been adopted by many medical centers worldwide.^{1 2 3 4 5} The rationale for screening is that early diagnosis permits early therapy, which in ...

THE terms "withholding of life support" and "withdrawal of life support" refer to the processes according to which various medical interventions either are not given to or are removed from patients with the expectation that they will die as a result. Life ...

PORPHYRIA cutanea tarda, which is the most common and readily treated form of porphyria in humans, results from a deficiency of uroporphyrinogen decarboxylase in the liver.^{1 2 3} It is characterized by cutaneous photosensitivity. The disease is usually ...

Presentation of Case

A 61-year-old woman was admitted to the hospital because of fever, chilliness, and nausea three weeks after an operation for carcinoma of the pancreas.

The patient was well until three months earlier, when she began to have persistent ...

In 1937, Hulusi Behçet, a Turkish dermatologist, published his observations on two patients with recurrent oral and genital aphthous ulcerations and hypopyon iritis (pus in the anterior chamber of the eye).¹ He proposed a viral origin for the new syndrome,...

Cystic fibrosis is a chronic disease of children and increasingly of adults; one third of the more than 15,000 patients listed in the registry of the North American National Cystic Fibrosis Foundation are older than 21 years. Respiratory complications ...

The article by Tandon et al.¹ in this issue of the Journal highlights one of the most important areas of research in clinical oncology today — the search for better means of predicting the risk of a recurrence in women after local and regional treatment ...

To the Editor: Truog and Fletcher's Sounding Board article (Aug. 10 issue)¹ is a creative addition to the debate on the use of anencephalic infants as organ donors. However, their argument is subject to several criticisms. Their proposed criterion for ...

To the Editor: In his report in the August 10 issue,¹ Dr. Zinman directs attention to a number of problems related to the administration of insulin. He fails, however, to come to the essence of why the physiologic replacement of insulin is an elusive ...

To the Editor: Could Lin et al. (Aug. 3 issue)¹ give their recommendations on how to treat transplant recipients with gouty arthritis? The care of these patients is complicated by the existence of a potentially serious drug interaction between ...

To the Editor: Cyclosporine is a potent immunosuppressive agent used in solid-organ transplantation, bone marrow transplantation, and autoimmune diseases. However, nephrotoxicity and systemic hypertension are serious side effects of cyclosporine therapy.^...

To the Editor: Wirt and collegues (Aug. 10 issue)¹ described a very interesting patient who had a new subpopulation of T cells expressing the alpha/beta form of the T-cell receptor (TCRα/β) but neither CD4 nor CD8. They suggested that the proliferation ...

To the Editor: Granulocytemacrophage colony-stimulating factor (rhGM-CSF) has recently entered clinical trials for patients with bone marrow failure.^{1 , 2} We are participating in a crossover study comparing the relative effectiveness of intravenous as ...

To the Editor: In their excellent discussion of the pathogenesis and treatment of anaerobic infection in the July 27 issue,¹ Styrt and Gorbach excluded vancomycin and parenterally administered aminoglycosides as antibiotics associated with ...

To the Editor: In 1987 the Department of National Health and Welfare in Ottawa instituted a surveillance program for Listeria monocytogenes infection in Canada to determine the public health importance of food contaminated with this organism. As a result ...

To the Editor: The paper by Little et al. (Aug. 17 issue)* reported evidence of an association between an infant's psychomotor development at one year and maternal use of alcohol during breast-feeding. The authors concluded that this effect was caused by ...

Knowledge in surgical pathology has grown considerably in the eight years since the previous edition of this textbook. The author has extensively revised and expanded the text, incorporating new and important information that makes for an instructive and ...

This atlas achieves its objective. Its many high-quality color photographs, both gross and microscopical, cover many of the most important lesions in the pathology of organ systems. The photographs and text were prepared in Germany, and the text was ...

This textbook covers the pathologic anatomy of the hollow alimentary tract and does not deal with the liver, pancreas, or biliary tree. The pathology of surgically resected specimens as well as biopsy specimens is covered. The book is organized into ...

This is a large, basic, and yet comprehensive textbook, whose great strength lies in its generous use of color images of both clinical and histopathologic material. Several plates are presented on each page, so that thousands of figures are included. They ...

This textbook provides detailed and comprehensive coverage of urologic pathology, including radiologic and clinical correlations. Unlike many textbooks of pathology, which are designed for pathologists and dominated by light-microscopical photographs of ...

Biomedical Science

ADP-Ribose Transfer Reactions: Mechanisms and biological significance. Edited by Myron K. Jacobson and Elaine L. Jacobson. 527 pp., illustrated. New York, Springer-Verlag, 1989. $80.

Assessment of the Elastic Properties of the ...

CALCIOTROPIC HORMONES

The 1st world conference will take place in Bologna, Italy, March 29–31.

Contact Prof. M. Cecchettin, Fondazione Clinica del Lavoro di Pavia, 27040 Pavia, Italy; or call (39) 385 60–561.

HMO POLICY

The conference will be held in ...

These guidelines are in accordance with the "Uniform Requirements for Manuscripts Submitted to Biomedical Journals." (The complete document is available in the June 12, 1982, issue of the British Medical Journal and the June 1982 issue of the Annals of ...