PLATELETS have an important role in atherosclerosis and its complications, such as acute coronary ischemia.^{1 2 3 4} The pathophysiologic mechanism by which platelets contribute to the acute manifestations of coronary artery disease is not fully understood. ...

STIFF-MAN syndrome is a rare, severe disease of the central nervous system characterized by progressive rigidity and painful spasms of the body musculature.^{1 2 3 4} Its cause is unknown. Symptoms are alleviated by drugs that enhance neurotransmission ...

LEFT ventricular hypertrophy, although infrequently noted on the electrocardiogram, imparts a substantial risk of morbidity and mortality.^{1 2 3} Echocardiography has permitted the reliable, noninvasive estimation of left ventricular mass^{4 5 6 7} and has ...

THE association among maternal epilepsy, anticonvulsant drugs, and an increased incidence of congenital abnormalities has been suspected for at least 25 years.¹ Despite numerous clinical and epidemiologic studies in humans that have documented well over ...

MOST infants with congenital diaphragmatic hernia die because their lungs are inadequate to support extrauterine life. This remains true despite advances in postnatal care, including preoperative stabilization,^{1 , 2} pharmacologic treatment of persistent ...

WHEN impaired older persons become ill, they are at high risk of death or functional deterioration that leads to institutionalization.^{1 , 2} Acute care hospitals have financial incentives to discourage the prolonged stays these patients may require to ...

IMMEDIATE vascular access is required for the optimal management of many emergencies in children, including cardiopulmonary arrest, burns, prolonged life-threatening status epilepticus, and shock due to trauma, dehydration, or sepsis.^{1 2 3} In many of ...

Presentation of Case

A 19-year-old woman was admitted to the hospital because of a painful mass in the right shoulder and jaundice.

The patient was well until approximately nine months earlier, when she began to have intermittent pain in the right ...

In recent years, physicians and patients have tended to move toward shared decision making. Although it sounds reasonable on the surface that patients and physicians should collaborate in making decisions about medical care, surprisingly little attention ...

IN forgiving coinsurance, a health care provider agrees to accept a third-party payer's reimbursement as sole and total compensation for services rendered. The practice is common; a recent survey suggested that 23 percent of patients with fee-for-service ...

The threat to the future of the physician-scientist is currently the focus of considerable attention. Addresses to the scientific community and articles in the medical press frequently express concern over projected shortages in the number of physicians ...

To the Editor: As a pediatric hematologist-oncologist I have intimate knowledge of the territory Ms. Wolf discusses (Jan. 18 issue).* Most of my patients are competent, but because they are minors, proxy decision making is the rule rather than the ...

To the Editor: We applaud the article by McCord and Freeman (Jan. 18 issue)* detailing excess mortality in Harlem and wish to plead for an examination of the root causes of the progressive deterioration of health and living standards in the predominantly ...

To the Editor: Phair and colleagues (Jan. 18 issue)¹ are to be complimented on their presentation of rates and markers of Pneumocystis carinii pneumonia in the Multicenter AIDS Cohort Study of homosexual men with human immunodeficiency virus type 1 (HIV-...

To the Editor: In his editorial on pancreas transplantation in diabetic patients (July 13 issue),¹ Dr. Tattersall commented on the proposed criteria developed at the University of Michigan to evaluate candidates for pancreas transplantation who do not ...

To the Editor: To date, there have been only two randomized prospective studies that have examined the effect of protein restriction on the progression of renal disease.^{1 , 2} The results of the more recent study, that of Ihle et al. (Dec. 28 issue),² are ...

To the Editor: Atrial infarction is an underrecognized clinical entity, and atrial rupture is a complication in fewer than 5 percent of the cases diagnosed.^{1 , 2} We report a rare case of an isolated right atrial infarction with rupture and epicardial ...

To the Editor: Upper-trunk injuries of the brachial plexus are rare in adults. We report a hitherto unrecorded cause of Erb's palsy.

A 26-year-old male backpacker reported weakness in his right arm after a trek in the mountains. The weakness started soon ...

Pregnancy's dark terror

Life snatched away, before it's begun,

No motion felt! When was the last?

Move, please move!

Doctor somber, half-hearted assurance

Urgent tests, seeing with sound

No movement, heart still

Floating quiet and dead.

A labor without ...

This general medical textbook is designed to be used by residents, students, and primary care physicians. It is revised annually and covers all aspects of internal medicine, including such subjects as psychiatry, ophthalmology, preventive medicine, ...

This book is intended for clinicians and scientists interested in atherosclerosis research. In the introduction, the editor writes, "The completed volume will hopefully provide researchers and physicians with information required to perform experiments ...

This book attempts an overview of "today's state of the art in managing acute myocardial infarction." It is devoted to coverage of the pathophysiology and application of diagnostic and therapeutic methods.

The book is well written and easy to read. Basic ...

The rapid development of new methods in echocardiography has required revisions of current textbooks. This book has been updated to include new information on two-dimensional, Doppler, and contrast echocardiography, and it introduces the techniques and ...

In their preface, Drs. Babior and Stossel state that hematology "is the most beautifully rational and therefore the most intellectually satisfying of all the disciplines of medicine." Such enthusiasm pervades their book. In this thoroughly revised and ...

Perhaps more than any other medical specialty, gastroenterology epitomizes the blend of science and art in medicine. The practice of gastroenterology may be viewed as a recurring challenge to distinguish organic from functional disease, predicated on the ...

This is the second edition of a major geriatric textbook. The editors note that significant advances in geriatric medicine have occurred since the previous edition in 1984: sophisticated approaches to urinary incontinence, falls, and other conditions; the ...

CALL FOR PAPERS AND PRESENTATIONS

Papers and presentations are now being accepted for the 2nd annual conference, entitled "Prenatal Drug Exposure: The Challenge to Education," to be held in Oakland, Calif., Jan. 18 and 19, 1991. Deadline for receipt is ...

Erythropoietin for the Treatment of Porphyria Cutanea Tarda in a Patient on Long-Term Hemodialysis (February 1, 1990; 322:315–7). The Système International (SI) values given for serum iron and total iron-binding capacity were too low by a factor of 100, ...

Anatomical Abnormalities in the Brains of Monozygotic Twins Discordant for Schizophrenia (March 22, 1990; 322:789–94). On page 792, in Table 2, the values for the third ventricle were transposed and should have been 0.71±0.28 cm³ for the unaffected twin ...