THE acquisition of a sexually transmitted disease as a result of sexual assault can have serious physical and emotional consequences. In previous studies, the prevalence of gonorrhea in victims of rape ranged from 2.5 to 13.3 percent, and the prevalence ...

MACROPHAGE Fc_γ receptors are important in the clearance of IgG-coated particulate antigens and immune complexes. The functional integrity of these receptors has been widely studied in patients with autoimmune disease, by measuring the clearance of Radio-...

TWENTY to 60 percent of patients with the Zollinger—Ellison syndrome have features of multiple endocrine neoplasia type 1 (MEN-1), an autosomal dominant disorder characterized by tumors of the parathyroids, the endocrine pancreas, and the anterior ...

SINCE the publication of our preliminary report describing the operative procedure and early improvement in lung function in the first two successful single-lung transplantations,¹ the procedure has been used to treat selected patients with end-stage ...

CYCLOSPORINE is the basis of the immunosuppressive regimen in most patients undergoing orthotopic liver transplantation.¹ It is a cyclic polypeptide that is produced by two species of fungi and is essentially insoluble in water.² Its oral form consists of ...

BIOMEDICAL research is rightly an enterprise involving international cooperation. Understanding the relative contributions of different countries to the effort is nevertheless useful, and one measurable indicator of productivity in biomedical research is ...

PATIENTS who have a first myocardial infarction deserve consideration as a special group. For the most part, the early mortality rate from a first infarction is roughly half the rate found in patients with a second or third infarction,^{1 , 2} and the long-...

Presentation of Case

A 38-year-old woman was admitted to the hospital because of abdominal pain, fever, and a rash.

She was well until two months earlier, when she experienced the onset of intermittent weakness, nausea, and vomiting that continued for six ...

IN the first edition of his Principles and Practice of Medicine, Sir William Osler stated that the clinical manifestations of uremia are caused by the retention of the excretory products. The nature of these poisonous ingredients is not yet known. It was ...

Students of human-organ transplantation have watched with attention the progress in lung transplantation during the past decade. A clinical reality since 1981, lung transplantation is now generally accepted as a useful procedure. Progress in its ...

To the Editor: Reducing the risk of human immunodeficiency virus (HIV) transmission among sexually active teenagers and young adults is a major public health concern.¹ Young people are advised to select potential sexual partners from groups at lower risk ...

To the Editor: In their article on the natural history of transfusion-associated infection with HIV, Ward et al. (Oct. 5 issue)* found that the majority of recipients of HIV-infected blood become seropositive. Their paper includes an analysis of factors ...

To the Editor: We read the Sounding Board article by Hallagan et al. (Oct. 12 issue),¹ on the use of anabolic—androgenic steroids by athletes, with considerable dismay. The authors' assertion that dissemination of "information on the adverse health ...

To the Editor: The paper by Pollare et al. (Sept. 28 issue)¹ comparing the effects of hydrochlorothiazide and captopril on glucose and lipid metabolism in patients with hypertension is of great interest, is well and carefully done, and may well help ...

To the Editor: Effective treatment of acute leukemia requires marrow-ablative chemotherapy, the success of which relies on transfusions of platelets and red cells during the period of marrow aplasia.¹ The patient with acute leukemia who is a Jehovah's ...

To the Editor: Benign essential blepharospasm may be severely incapacitating. The disorder is characterized by bilateral, progressively debilitating spasm of the orbicularis oculi and upper facial muscles, ultimately interfering with vision. Current ...

To the Editor: A 95-year-old woman with dementia who was not a native speaker of English had been a resident of a skilled-nursing home for nearly one year when she was noted to have increased pharyngeal secretions. Marked pulmonary congestion developed ...

To the Editor: Dr. Benjamin's article (Oct. 26 issue)¹ suggests that mid-19th-century medicine involved a homogeneous group of general practitioners, "virtually indistinguishable from one another." According to Starr's The Social Transformation of ...

To the Editor: The sample size required in a randomized trial depends on the alpha (or type I) error and the beta (or type II) error deemed acceptable and on the size of the treatment effect sought (called the delta). We have examined all the randomized ...

To the Editor: The article by Alexander Leaf (Sept. 28 issue)* raises a number of excellent points. Rigorous studies to evaluate diagnostic-testing strategies and treatment methods are surely needed. Although some of these methods may be shown to be ...

Not even reading,

I lie in bed breathing air:

A bear in winter.

Or perhaps a small snail

Creeping with care on sharp stones

Seeking a safe spot.

I give myself orders:

Conjugate love in Latin;

Recite your mantra;

Think of the stone couch —

Cleopatra's. Her ...

Creative Solutions

Outrageous Perspectives on Problem Solving. We often look to logic instead of creativity for "true answers" to life's struggles. This workshop explores the creative process and teaches skills for problem solving. We will examine (1) ...

The second edition of the Oxford Textbook of Psychiatry is a crisply written, compact, consistent, and thoughtful introduction to the field. The book opens with a pleasantly short preface and moves on to a description of the signs and symptoms of ...

In the introduction to their popular textbook, Diseases of the Nervous System: A Textbook of Neurology and Psychiatry (3rd edition, Philadelphia and New York, 1919), Jelliffe and White explained the difficulty of writing such a book by observing that "the ...

The first of these books, The Eating Disorders, is an up-to-date, state-of-the-art textbook on all that can happen to us and our appetites as regards food intake and human behavior. If it fails to read like a novel, it should not be expected to do so, ...

There has been a growing interest, particularly in the United States, in that peculiar gray zone of clinical practice between psychiatry and neurology. In psychiatry, there has been a move away from psychodynamic toward biomedical formulation, especially ...

The recent increase in suicide among young people has been alarming. The secretary of health and human services therefore established the Task Force on Youth Suicide. Researchers, clinicians, and educators convened to assess the available information, ...

The sexual abuse of children, and particularly intrafamilial sexual abuse, is one of the most pernicious forms of child maltreatment, carrying implications of both immediate and long-term effects. While incest has existed throughout recorded time, strong ...

The first book here, edited by While, is a timely review and synthesis by British researchers and clinicians of health care problems associated with life in the inner city. Each chapter deals with problems specific to particular age groups of inner-city ...

OCCUPATIONAL MEDICINE

The 11th annual update will be held in St. Paul on March 23.

Contact Midwest Ctr. for Occupational Health and Safety, Program in Cont. Educ, 640 Jackson St., St. Paul, MN 55101; or call (612) 221–3992.

SCIENCE AND MEDICAL WRITERS

The ...