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August 24, 1989  Vol. 321 No. 8

Original Articles
485-491

    HUMAN parvovirus B19 is a small, single-stranded DNA virus discovered in asymptomatic blood donors in 1975.1 , 2 It was later found to be associated with aplastic crisis in patients with chronic hemolytic anemia,3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18and ...

    492-496

    IN 1965, Bethune and Nelson1 described eight patients with hypopituitarism and hyponatremia in whom the hyponatremia appeared to be due to water retention rather than to hypotonic dehydration. Ahmed et al.,2 using a very sensitive bioassay, found ...

    497-501

    TRICHOTILLOMANIA, a form of traction alopecia described a century ago by Hallopeau,1 is characterized by an irresistible urge to pluck one's own hair. This disorder, classified as a disturbance of impulse control,2 has an unknown natural history and ...

    501-507

    CURRENT treatments to prevent stroke in high-risk patients include vascular surgery, anticoagulants, and platelet antiaggregating drugs1 , 2; the value of these therapies remains controversial. Two randomized studies of carotid endarterectomy3 , 4 have ...

    Special Article
    508-513

    RECENT reports have called attention to the widespread lack of health insurance nationally and in California.1 2 3 4 5 6 Nine to 18 percent of the nonelderly U.S. population lacks public or private health insurance.2 , 7 8 9 During 1984, 17 percent of all ...

    Mechanisms of Disease
    513-518

      A PREVIOUSLY undescribed protein, called insulinoma- or islet-amyloid polypeptide (IAPP), was recently identified as the principal constituent of amyloid deposits in a human insulin-producing tumor (insulinoma).1 This same protein was subsequently found ...

      Medical Intelligence
      519-523

      PARVOVIRUS B19 is the etiologic agent of transient aplastic crisis, an acute episode of bone marrow failure in persons with underlying hemolysis.1 , 2 In tissue-culture studies, parvovirus B19 infects3 and replicates4 in erythroid progenitor cells. The ...

      Case Records of the Massachusetts General Hospital
      524-535

      Presentation of Case

      A 74-year-old woman was admitted to the hospital because of vertigo, anorexia, and weight loss.

      She was well until about two months earlier, when vertigo developed. One month before entry she was examined before a scheduled cataract ...

      Editorials
      536-538

        The two articles on human parvovirus B19 infection in this issue of the Journal 1 , 2 make important contributions to our understanding of the epidemiology and treatment of the disease. Since its discovery in 1975, B19 has been shown to have a number of ...

        538-539

        IN their classic paper describing the clinical syndrome of inappropriate secretion of antidiuretic hormone (SIADH), Schwartz et al. deduced that the abnormal combination of hyponatremia with concentration of the urine and renal sodium wasting was probably ...

        539-541

        "I know it's stupid. I feel like a crazy person, but I know that I'm not crazy!" These are typical statements from a patient with obsessive–compulsive disorder who for the past 10 years has spent more than six hours a day washing her hands, although she ...

        541-542

          Americans have no right to health care. In this respect, we stand almost alone among the industrialized nations of the world. Only some of our citizens pay the price directly for this lapse in commitment, however. In this issue of the Journal, Braveman ...

          Correspondence
          542-543

          No extract is available for articles shorter than 400 words.

          543-544

          No extract is available for articles shorter than 400 words.

          544-545

          No extract is available for articles shorter than 400 words.

          545

          To the Editor: Altitude illness has been called a disease of "protean manifestations."* Early recognition of the symptoms and a high index of suspicion are necessary at altitudes to prevent needless deaths. However, familiarity with the signs and ...

          545-546

          To the Editor: In experimental autoimmune encephalomyelitis (EAE) — the animal model of the early "encephalitic phase"1 of multiple sclerosis — an increase in venular permeability precedes the invasion of the parenchyma of the central nervous system by ...

          546

          To the Editor: It is generally agreed that torsion and ischemia of adnexa will require treatment by adnexectomy.1 Since torsion of the adnexa in female patients usually occurs at or before the age of reproduction,2 we conducted a study to determine ...

          546-547

          To the Editor: A high proportion of women who have intrauterine contraceptive devices (IUDs) inserted have them removed within the first year because of symptoms attributed to the device.1 A substantial proportion conceive with the device in situ.2 ...

          547

          No extract is available for articles shorter than 400 words.

          548

          No extract is available for articles shorter than 400 words.

          548-550

          No extract is available for articles shorter than 400 words.

          Occasional Notes
          550-551

          No extract is available for articles shorter than 400 words.

          Book Reviews
          552

          Here is an up-to-date review of the pathophysiology of heart failure and its diagnosis and treatment. More than one third of its pages are devoted to an overview, cardiac muscle physiology, vascular and neurohumoral factors, the renin–angiotensin–...

          552

          In 1929, Werner Forssmann performed the first cardiac catheterization, on himself, and subsequently shared the Nobel prize for his contributions to the field of invasive cardiology. By 1960, invasive cardiology had proved to be an indispensable tool for ...

          552-553

          The practice of cardiology and cardiovascular surgery has evolved dramatically over the past decade, with major technological advances in diagnosis and treatment. Nowhere is this more evident than in coronary care and cardiothoracic surgical intensive ...

          553

          There are a number of comprehensive books available in pulmonary medicine. This one compares favorably with them. In its fourth edition, it has been appreciably expanded. There are two volumes, 11 parts, 78 sections, and 1660 pages. Sixty contributors, ...

          553-554

          Regrettably, increased life expectancy is not yet accompanied by prolonged youth. Elderly people must endure the ravages of senescence, which are all too apparently mirrored by the skin, a victim of both biologic aging processes and environmental ...

          554

          The editor of this three-volume work suggests that it is appropriate for undergraduates (probably undergraduate medical students), residents, postgraduate scholars, and practicing physicians. I am not sure how many of these potential readers will want to ...

          Books Received
          554-555

          Health Policy

          Administration and Supervision in Laboratory Medicine. Second edition. Edited by John R. Snyder and Donald A. Senhauser. 525 pp. Philadelphia, J.B. Lippincott, 1989. $39.50.

          Children and Health Care: Moral and social issues. (Philosophy and ...

          Notices
          555-556

          EUROPEAN UNION FOR SCHOOL AND UNIVERSITY HEALTH AND MEDICINE

          The congress will be held in Paris, Sept. 18–21.

          Contact AFPSSU, 53 rue Truffaut, 75017 Paris; or call (33) 1 42–29–50–30.

          RADIOLOGY ON ISCHIA

          The 11th annual international radiology congress ...

          Corrections
          556

          No extract is available for articles shorter than 400 words.

          556

          No extract is available for articles shorter than 400 words.

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