CIMETIDINE (N"-cyano-N-methyl-N'-[2-[[(5methyl- 1H-imidazol -4-yl)methyl] thio]ethyl] guanidine) is a histamine H₂–receptor antagonist that has been widely used in the treatment of peptic ulceration. In 1988 it was the sixth most frequently prescribed ...

OSTEITIS FIBROSA is the bone abnormality most frequently found in patients with end-stage renal disease. Histologically, it is characterized by increased rates of bone formation and bone resorption in association with varying amounts of marrow fibrosis.¹ ...

SEPTIC SHOCK, a life-threatening complication of serious bacterial infections, is a major cause of irreversible hypotension, multiple organ dysfunction, and death.^{1 2 3 4} Endotoxin is one of the principal bacterial components that interacts with the host ...

DURING the course of one month, three recipients of renal allografts presented to our services with acute gouty arthritis. All three were receiving cyclosporine and prednisone for maintenance immunosuppression. A review of the literature at that time ...

THERE is substantial evidence that endogenous hormones are involved in the causation of breast cancer,¹ and that breast cancer can be induced in laboratory animals by exogenous estrogens.² Epidemiologic studies of the risk of breast cancer after treatment ...

(Second of Two Parts)

Another clinical syndrome for which a putative anaerobic pathogen has been tentatively identified is nonspecific vaginitis, now often referred to as anaerobic vaginosis. In the past this condition was thought to be caused by ...

DRUG therapy in the elderly is complicated by many factors unique to this age group. Because it requires careful individualization, such therapy should be based on the principles of pharmacokinetics. Multiple disease processes, environmental influences, ...

Presentation of Case

A 12 1/2-week-old boy was admitted to the hospital because of tachypnea and bilateral rales.

The child was born of a full-term pregnancy; the second trimester was complicated by streptococcal pharyngitis, which was treated with ...

Replacement of the kidney's excretory function by dialysis has prolonged life, but it has also revealed the extent and importance of the organ's endocrine function. Lacking the kidney's endocrine contributions, patients undergoing long-term maintenance ...

AN epidemiologic study in this issue of the Journal ¹ could change the way we think about postmenopausal hormone replacement. In the report, 23,244 Swedish women identified from prescription records for the noncontraceptive use of estrogen were followed ...

Sudden death or acute and extensive myocardial infarction are common presenting manifestations of coronary artery disease.^{1 , 2} In attempting to determine whether screening tests can identify persons at risk of sudden death, three studies in which ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: We were gratified to see further attention drawn by the paper of Almquist et al. (Feb. 9 issue) ¹ to the important area of orthostatic stress testing for the induction of vasovagal syncope in patients with unexplained syncope. In our ...

To the Editor: Despite the widespread use of iron, cases of secondary iron overload are exceptionally rare.^{1 , 2} We present a case of iron overload after the prolonged administration of intramuscular iron.

A 63-year-old woman was found to have a raised ...

To the Editor: Communion wafers made from wheat flour may provoke symptoms in patients with celiac disease,^{1 , 2} although many believe their gliadin content is insufficient to damage intestinal mucosa. Gliadin was extracted from gluten by ethanol ...

No extract is available for articles shorter than 400 words.

It goes almost without saying that it is more difficult to write a concise book on a subject than it is to write a long, scholarly one. One reason for this is that the expert has a misplaced sense of what will be important to the nonexpert and too great a ...

The acquired immunodeficiency syndrome (AIDS) epidemic needs no introduction. The human immunodeficiency virus (HIV) has changed the nature of medical care in our major cities, created fear with respect to sexual behavior, raised the specter of the ...

No extract is available for articles shorter than 400 words.

"The fundamental problem facing scientists and clinicians in Rheumatology is that so little is known about the biology of joints. It is our view that a real interface between basic and clinical science offers the best chance of gaining a better ...

This is the third edition of the separate publication of the virology section of Zinsser's Microbiology. It was written by a recognized leader in the field of virology and is intended for advanced undergraduates, medical students, and those taking ...

ADVANCED MANAGEMENT PROGRAM FOR CLINICIANS

Applications are now being accepted from outstanding health care professionals interested in the development of management skills. Deadline for receipt is Aug. 5.

Contact Cindy Mazur, AMPC, New York Univ., 738 ...

These guidelines are in accordance with the "Uniform Requirements for Manuscripts Submitted to Biomedical Journals." (The complete document is available in the June 12, 1982, issue of the British Medical Journal and the June 1982 issue of the Annals of ...