ALTHOUGH chewing willow bark, which has L aspirin-like properties, was prescribed for pain relief by Hippocrates in the fifth century B.C., the possible role of aspirin in reducing the risk of cardiovascular disease has been recognized only very recently. ...

AN increased risk of acute myeloid leukemia (AML) in patients with Hodgkin's disease treated with combinations of cytotoxic drugs, with or without irradiation, has been reported by many international centers and cooperative groups.^{1 2 3 4 5 6} Explanations ...

TREATMENT of childhood acute lymphoblastic leukemia is now regarded as curative, and the majority of children with acute lymphoblastic leukemia will survive to adulthood.¹ As a result, there has been increasing concern about the effects of therapy on ...

THE recent availability of purified recombinant human erythropoietin in large quantities has allowed clinical trials of its efficacy in treating anemia.^{1 2 3 4} With the use of this recombinant hormone as a tracer and immunogen, it has also been possible ...

CHRONIC renal failure almost invariably results in anemia. Suggested contributors to this anemia include a relative or absolute deficiency of erythropoietin,^{1 , 2} decreased survival of red cells,³ and retained inhibitors of erythropoiesis.⁴ Although ...

THE development of specific antiviral drugs that are minimally toxic to normal cells has ushered in a new era of antiviral therapy. The advent of this therapy is especially timely in the light of the threat to the lives of immunocompromised patients from ...

Presentation of Case

A 79-year-old man was admitted to the hospital because of fever, abdominal pain, and an inflamed right eye.

The patient felt well until six days earlier, when he ate a huge turkey sandwich. Several hours later he began to experience ...

The salutary effects of willow bark have been known to several cultures for centuries. Salicin, the active ingredient, is a bitter glycoside from which sodium salicylate was isolated in 1829 by Leroux, who demonstrated its antipyretic effects.¹ The ...

Current therapy cures most children with acute lymphoblastic leukemia (ALL). Two thirds of the patients have favorable prognostic features at the time their ALL is diagnosed, and the results of the latest clinical trials strongly suggest that almost 90 ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: The report by McFarland et al. (Jan. 26 issue)* contributes new information about the acquisition of Clostridium difficile by hospitalized patients. A number of points were omitted from the results that, if available, would be useful in ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Here is a valuable resource book on Canadian health care services, aimed at students, health workers, and users, according to the authors. Interspersed with many informative tables and figures are discussions of an impressive array of topics in Canadian ...

With its serious title and its pale-blue cover showing an old photograph of a family of hookworm sufferers, this slender book confirms the adage: Do not judge a book by its cover. The book is an attractive collection of seven essays by professors of ...

This edited collection of historical articles on the variety of healing systems that have prevailed in America is a valuable addition to the historiography of medicine. The essays consider the preeminent alternative medical systems of the past two ...

This compendium of 74 interviews was obtained from people who work at Columbia–Presbyterian Medical Center. The interviewer, a medical sociologist, spent many days, nights, and parts of weekends at the hospital from 1985 to 1988 talking to security guards,...

This books attempts a monumental task: the characterization of American hospitals in the 20th century. That it succeeds so well is precisely because it does not strain to size up its subject, which by its very nature resists ready characterization. ...

Historically and conceptually, ethics has been a branch of philosophy distinct from the empirical sciences. This distinction was not seriously challenged until the 19th century, when evolutionary biologists sought to derive moral norms from the facts and ...

HEALTH OF INNER CITIES AND URBAN AREAS

The international conference will be held in Cardiff, Wales, Sept. 4–7.

Contact Lori Butterworth, Meeting Point West, Paramount House, 77 Mutley Plain Lane, Plymouth, Devonshire PL4 7DS, United Kingdom; or call (44) ...

America's social contract with its physicians, historically based on a binding trust reflected in the self-regulated nature of the profession, is being subjected to new questions that stem from the rapidly changing nature of medical care delivery and ...