RETINOBLASTOMA is a cancer of the retina that appears predominantly in children younger than four years of age. It occurs in both hereditary and nonhereditary forms and is the eighth most common cancer among children younger than 15.^{1 , 2} Roughly 40 ...

BOTH amantadine and rimantadine have been shown to be effective in the prevention and treatment of infections with influenza A virus in certain clinical settings.^{1 2 3 4} At conventional doses rimantadine has the advantage of a lower risk of adversely ...

TRANSIENT loss of consciousness may be caused by intermittent atrioventricular block or sinus-node dysfunction.^{1 , 2} When syncope occurs infrequently and the electrocardiogram is otherwise normal, it may be difficult to obtain electrocardiographic ...

ACUTE mountain sickness frequently strikes travelers who rapidly ascend to altitudes above 2500 m.¹ It is characterized by headache, lassitude, anorexia, nausea, and vomiting. Although often disabling, it is usually self-limited.² However, it occasionally ...

BOTH transient and long-lasting neurobehavioral impairments have been found in a group of young, fit mountaineers after an expedition to climb Mount Everest (altitude, 8848 m; barometric pressure, about 34 kPa [253 mm Hg]).¹ Before and after the ...

EACH year since 1986, the Health Care Financing Administration (HCFA) has compared the annual mortality rates, adjusted for case mix, for all hospitals in the United States that serve Medicare patients. One purpose of these analyses is to assess the ...

ATHERAPEUTIC attack on the immune system is initiated in anticipation of or in response to immunologically mediated tissue damage. Drug regimens seek to inhibit selectively the T-cell and B-cell elements that permit adaptive, specific recognition of ...

Presentation of Case

A 72-year-old woman was admitted to the hospital because of anorexia, weight loss, and a right pleural effusion.

She was well until 4 1/2 years earlier, when a mass was discovered in the upper outer quadrant of the right breast. A ...

"For the first time ever, national health insurance has a serious chance of passing the Senate during this Congress." So began an article in The Wall Street Journal on July 16, 1979.¹ Just over a decade later, similar predictions of universal health ...

To the Editor: Some proarrhythmia must be expected with the use of all antiarrhythmic drugs. The results of any antiarrhythmic drug trial should therefore be considered in terms of an antiarrhythmia–proarrhythmia equilibrium, with beneficial outcome ...

No extract is available for articles shorter than 400 words.

To the Editor: Zidovudine (AZT) is a nucleoside analogue that inhibits the replication of human immunodeficiency virus (HIV) in vitro by an inhibitory effect on the reverse transcriptase of the virus. The DNA polymerase of the hepatitis B virus (HBV) has ...

To the Editor: Turhan and colleagues observed in their article (June 22 issue)¹ that of 12 recipients of marrow transplants evaluated, 1 recipient had monoclonal and another oligoclonal hematopoiesis in donor hematopoietic cells. Monoclonal ...

No extract is available for articles shorter than 400 words.

To the Editor: In October 1987, a 57-year-old woman was admitted to the hospital for breathlessness and right-sided chest pain of four months' duration. Her erythrocyte sedimentation rate was 100 mm per hour. A CT scan disclosed thickening of the ...

No extract is available for articles shorter than 400 words.

To the Editor: The Sounding Board article by Miles et al. (July 6 issue)¹ on institutional conscience brings needed attention to the relatively primitive status of our efforts to define the appropriate balance between the competing moral claims of ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

In this edition of Rob and Smith's Trauma Surgery, the book has been extensively revised and expanded. There are more than 100 contributors from many countries. This book is an atlas of surgical technique; it is not a textbook on trauma. An example of the ...

Although pediatric surgery is still relatively young, its scope has grown considerably. The practice of the pediatric surgeon encompasses many diseases in a variety of organ systems, ranging from the commonplace, such as pyloric stenosis, to the unusual, ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Health Policy

Animal Research and Ethical Conflict. By M.T. Phillips and J.A. Sechzer. 251 pp. New York, Springer-Verlag, 1989. $69.

Caring and Responsibility: The crossroads between holistic practice and traditional medicine. By June S. Lowenberg. 296 ...

DRUG INFORMATION ASSOCIATION

The following workshops will be held: "Medical Communications DIA Subgroup Annual Workshop" (Charleston, S.C., Jan. 29 and 30) and "Legal Liability for the Pharmaceutical Industry and Its Employees — How to Minimize the Risk" (...

Health insurance programs reflect the cultural beliefs, political priorities, and medical imperatives of the countries in which they evolve. Across a continuum that features more or less reliance on government or private mechanisms, most Western countries ...