EPIDEMIOLOGIC studies of irradiated populations clearly indicate that the female breast is a highly radiosensitive organ.¹ Most such studies, however, have been restricted to women exposed to ionizing radiation during adolescence or adulthood. Early ...

HIGH doses of ionizing radiation, such as x-rays and gamma rays, have been shown to increase the risk of breast cancer in women.^{1 2 3 4} It is therefore important to quantify the risk associated with lowdose exposures to permit a risk–benefit evaluation of ...

BETWEEN 25 and 60 percent of preschool children cared for in group day-care centers shed cytomegalovirus (CMV) without apparent symptoms.^{1 2 3 4} These high rates of infection with CMV are due to child-to-child transmission of the virus.⁵ The mothers of ...

PATIENTS who undergo peripheral vascular surgery are at increased risk for postoperative cardiac complications,¹ presumably because of the high prevalence of important coronary artery disease.² However, assessing cardiac risk is difficult because these ...

IN Asian countries where infection with hepatitis B virus (HBV) is hyperendemic, most people are infected during childhood^{1 2 3 4 5} through either perinatal (mother-to-newborn) or child-to-child transmission.^{6 , 7} Since 1975, nearly one million refugees ...

GUIDELINES for medical practice are produced with increasing frequency in North America.^{1 , 2} The Physician Payment Review Commission has recently recommended making them even more available, "so that they are incorporated into physicians' practices."³ ...

DESPITE early observations suggesting an inverse relation between serum levels of high-density lipoprotein (HDL) cholesterol and coronary disease,^{1 2 3} the possible protective role of HDL in atherogenesis received little attention until its "rediscovery" ...

Presentation of Case

A 48-year-old woman was admitted to the hospital because of the adult respiratory distress syndrome and left flank pain.

She was well until eight months earlier, when she was admitted to another hospital because of chest pain that was ...

The cardiac risk associated with noncardiac surgery is due primarily to clinically silent or apparently stable coronary artery disease that is unmasked by the stress of surgery. Since it is too hazardous and expensive to perform coronary angiography on ...

The first vaccine against human hepatitis B virus was licensed for use in the United States in 1981 and became commercially available in 1982.¹ The development of this vaccine represented a milestone in medicine and was the product of two decades of ...

Since the acquired immunodeficiency syndrome (AIDS) was first described in 1981, thousands of papers have been written on all aspects of the disease, from basic virology through social psychology. With few exceptions,^{1 , 2} however, little has been said ...

To the Editor: Widespread interest in both the safety of blood transfusion and the public perception of that safety prompts us to offer additional analysis and commentary on the report by Cohen et al. (May 4 issue).*

Since this study identified only one ...

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No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

The appellation "textbook" implies that a work is a standard of reference, an authoritative and comprehensive treatise. Also implicit in this designation is the development of a taxonomy for the codification of diffuse and disparate concepts and subject ...

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No extract is available for articles shorter than 400 words.

This author is renowned for his clinical tales. Whether exploring the phenomenology of illness through his own leg injury or the ambivalent awakenings of comatose patients with Parkinson's disease, Sacks' medical gaze is filtered through the humanity of ...

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No extract is available for articles shorter than 400 words.

The appearance of this revised edition has been awaited with keen anticipation. The first edition has been out of print for some years and has been in an enviable position as the only available work devoted exclusively to the neuropathology of the ...

No extract is available for articles shorter than 400 words.