IT is known that blood transfusion can immunize a recipient and lead to the formation of leukocytotoxic antibodies,¹ which may be associated with the rejection of allografts.² It was therefore surprising to learn that transfusion can also have a ...

CHRONIC granulomatous disease is a clinical syndrome characterized by recurrent, severe pyogenic bacterial or fungal infections and phagocytic-cell dysfunction. The diagnosis is confirmed by the demonstration of defective granulocyte responses to ...

THE ability to produce antibody in response to specific protein antigens has been shown to be controlled by autosomal dominantly expressed Class II genes of the major histocompatibility complex (MHC) in mice and other species.¹ The demonstration of such ...

VENTRICULAR late potentials are bursts of low-amplitude potentials that prolong the QRS complex on a signal-averaged surface electrocardiogram. Their presence in patients with acute myocardial infarction has recently been described as a marker for the ...

SHOULD Kellogg advertise All-Bran cereal as helping to reduce the risk of cancer?¹ Should federal requirements for labeling nutrients mandate the disclosure of the cholesterol, fatty acid, and fiber content on food packages? Do food-labeling regulations ...

THE development of a rational therapy against the etiologic agent of the acquired immunodeficiency syndrome (AIDS)^{1 2 3} was made possible by the discovery that a cytopathic retrovirus, now called the human immunodeficiency virus (HIV), caused the ...

Presentation of Case

A 60-year-old man was admitted to the hospital because of cranial-nerve palsies, ataxia, and a left-sided sensory deficit.

The patient was well until 5 1/2 months earlier, when he was first admitted to this hospital because of ...

One of the most critical interactions that initiate an immune response is the genetically determined signal provided by molecules encoded by the major histocompatibility complex (MHC) of genes. The human MHC, termed the HLA region, includes HLA Class I (...

Fast-food restaurants are here to stay and are gaining patronage.¹ But how nutritious are the meals they serve? How should health care professionals discuss the consumption of fast foods with patients and their families responsibly yet practically?

Every ...

To the Editor: Just one week after a Journal editorial on the disclosure of investigators' financial ties (April 6 issue),¹ there was a Sounding Board article on isotretinoin (Accutane) by Dr. Robert Stern (April 13 issue),² in which no disclosure was ...

To the Editor: In an analysis of their data on recurrence of thyroid nodules after surgery in patients irradiated for benign conditions, Fogelfeld et al. (March 30 issue)¹ report that 19.5 percent of the patients had a recurrence during a median follow-...

To the Editor: In their study, Chavers et al. (April 13 issue)¹ address a crucial point regarding the validity of using the level of urinary albumin excretion to predict the likelihood of overt diabetic nephropathy in a given patient. However, their ...

To the Editor: In their study of the survival of ¹¹¹In-labeled autologous platelets in 10 patients with acute and 9 with chronic autoimmune thrombocytopenia during the thrombocytopenic phase and after recovery, Gernsheimer et al. (April 13 issue)¹ state, ...

To the Editor: The clinical implications of heterozygosity for β-thalassemia are largely unknown.¹ The high prevalence of β-thalassemia carriers in areas that once had the highest incidence of malaria has given rise to the hypothesis that β-thalassemia ...

To the Editor: Minuk and Lewkonia (Feb. 27, 1986, issue)¹ suggest that the familial concurrence of multiple sclerosis and idiopathic inflammatory bowel disease (ulcerative colitis or Crohn's disease) may represent shared genetic causes, environmental ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

George Frideric Handel was the first of the great entrepreneurial composers. Giants often become the centers of myth, and Handel was no exception. The Handelian myths include serious solemn religiosity, an asexual life in the service of his music, two ...

The author of this basic textbook has certainly taken on a herculean task. No other field of radiology has borne the brunt of new methods of imaging more than neuroradiology. Every new method, especially magnetic resonance imaging, has contributed ...

No extract is available for articles shorter than 400 words.

The management of stroke is fraught with such controversy that after sustaining a degree of cerebrovascular compromise a patient may be given some aspirin and sent home or prepared for major surgery — depending solely on proximity to a particular ...

Despite a decrease in incidence over the past three decades, stroke remains the third leading cause of death in the United States. The diagnosis and management of stroke are complicated by a morass of conflicting studies and recommendations, often made on ...

The appearance of a book with "handbook" in its title is an exciting event for child neuropsychology, heralding perhaps a further consolidation of elements from clinical child neurology and psychiatry, adult neuropsychology, school psychology, and even ...

Much of the literature on aging and human neurobiology falls into one of two subgenres: that emphasizing geriatrics and that emphasizing neurology. In this monograph, Giaquinto, chief of neurology at a rehabilitation hospital in Rome, has endeavored to ...

The contributors to this extensive work include 16 psychiatrists or psychologists, 7 specialists in rehabilitation medicine, anesthesiology, and neurosurgery, 5 in orthopedic surgery, and 3 in family medicine, pharmacology, neurology, physiology, and "...

1990 PEDIATRIC EXAMINATIONS

The Sub-Board of Pediatric Hematology–Oncology of the American Board of Pediatrics will administer its next certifying examination on July 20, 1990. Registration will extend from Oct. 1, 1989, to Dec. 30, 1989.

The Sub-Board of ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.