Dramatic declines in the prevalence of both rheumatic fever and serious infection caused by group A streptococci have been observed throughout the 20th century in much of the Western world.^{1 2 3 4} The decline has been thought by some^{2 , 3} to be related in ...

Herpes simplex virus type 2 (HSV-2) most commonly infects the genitalia and is usually transmitted sexually.^{1 2 3 4 5} Perinatal transmission is comparatively infrequent but results in severe, often fatal disease in newborns.⁶ After infancy, HSV-2 ...

A Basic question about congenital hypothyroidism is whether thyroid hormone is transferred from the mother to the hypothyroid fetus, especially in late gestation. This question is raised by observations of neonates with severe hypothyroidism, most of whom ...

YERSINIA ENTEROCOLITICA is rapidly emerging worldwide as an enteric pathogen associated with a wide spectrum of clinical and immunologic manifestations. The clinical illness caused by this pathogen ranges from self-limited enterocolitis to potentially ...

Acute graft-versus-host disease has been described in immunocompromised patients receiving nonirradiated blood products.^{1 2 3} In addition to the involvement of the skin, liver, and gut typically seen in graft-versus-host disease after bone marrow ...

The advent of new immunosuppressive drug regimens has produced a substantial improvement in organ-allograft survival during this decade.^{1 2 3 4 5} However, the treatment of organ-transplant recipients still involves the lifelong use of immunosuppressive ...

Presentation of Case

A 59-year-old woman was admitted to the hospital because of a sore throat, fever, and profound weakness.

She was well until one month earlier, when facial palsy developed and resolved in about one week. Six days before entry a sore ...

THE syndrome of cretinism, the irreversible mental retardation that occurs in infants with untreated hypothyroidism, is the best evidence that thyroid hormone is required for normal human development. Nonetheless, most newborn infants with congenital ...

An editorial by Relman proclaims, "Universal Health Insurance: Its Time Has Come."¹ Other recent Journal articles recommend various consumerchoice health care systems,^{2 , 3} and the report of the National Leadership Commission on Health Care proposes what ...

The right of patients to forgo life-sustaining treatment has been well established in health law and medical ethics. But do patients also have a right to compel health care facilities or their staffs to participate in carrying out such a decision? What ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: The article by Avorn et al. (Jan. 26 issue)* adds to the confusion about appropriate homes for society's frailest people — those who are mentally ill or neurologically impaired. Their study implies that rest homes are negligent and frees ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

With the Food and Drug Administration's approval of gadolinium–DTPA (diethylenetriamine pentaacetic acid) in 1988 for intracranial neuroradiologic clinical magnetic resonance imaging (MRI) and in 1989 for spinal MRI examinations, there has been a sudden ...

The intent here is to provide an atlas and reference for emergency ward physicians who lack experience in radiology, as a guide to the interpretation of skull radiographs of victims of head trauma. The authors acknowledge the limited role that skull ...

During the 1950s and early 1960s, when pediatric cardiac surgery was in its infancy, the physiologic information obtained at cardiac catheterization was usually sufficient to permit planning of the appropriate palliative procedures — a Blalock-Taussig ...

A variety of new instruments and methods as well as improved techniques of cardiac imaging have been introduced in the past five years. A major task facing both the clinician and the imaging specialist is to determine which of these is the best for any ...

The receipt of these books is acknowledged, and this listing must be regarded as sufficient return for the courtesy of the sender. Books that appear to be of particular interest will be reviewed as space permits.

Addresses of most overseas publishers ...

Notices submitted for publication should contain a mailing address and phone number of a contact person or department. We regret we are unable to publish all Notices received.

HEALTH CARE AND THE POLITICS OF CHANGE

The symposium will be held in Colorado ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

These guidelines are in accordance with the "Uniform Requirements for Manuscripts Submitted to Biomedical Journals." (The complete document is available in the June 12, 1982, issue of the British Medical Journal and the June 1982 issue of the Annals of ...