EPIDEMIOLOGIC surveillance data in the United States have suggested an important association between tuberculosis and the acquired immunodeficiency syndrome (AIDS). Increasing rates of tuberculosis have been noted in areas with high concentrations of AIDS ...

INSULIN-DEPENDENT diabetes mellitus (IDDM) is thought to be due to an autoimmune process that destroys the beta cells.¹ The sequence of events leading to the total destruction of beta cells is unknown. Attempts at preserving the beta cells in patients ...

OSTEOPOROSIS is a disorder associated with considerable morbidity and mortality.¹ Since no safe and effective treatment is currently available that replaces the bone already lost after menopause and during aging, preventive strategies must be devised so ...

THE cause of polycystic ovary syndrome is the subject of intense controversy.¹ The most widely accepted hypothesis is that it is the result of a complex cycle in which the peripheral formation of estrone from androstenedione, which originates in part from ...

MUCH of the knowledge used to design therapeutic regimens has been gained in only one or two ethnic groups. Many studies of drug effects in humans do not describe the ethnic or racial background of their subjects, and of those that do the majority have ...

AMERICAN interest in the Canadian health care system appears to be on the rise, as evidenced in a recent three-part article by Iglehart^{1 2 3} in the Journal. Such interest has been intermittent in the past, depending in part on the position of national ...

TRANSIENT global disorders of cognition and attention, usually referred to as delirium or acute confusional states, are one of the most common and important forms of psychopathology in later life.^{1 2 3 4 5 6} Hodkinson has stated, "Acute mental confusion ...

Presentation of Case

A 32-year-old man was admitted to the hospital because of the acquired immunodeficiency syndrome (AIDS), dyspnea, substernal pain, and an apparent cavitary lesion in the right lung.

The patient was a practicing homosexual with a ...

The study by Zhou et al. in this issue of the Journal ¹ compares the physiologic effects and the pharmacologic disposition of propranolol in a group of American whites and a group of Orientals of Chinese descent. The reason for the study was the ...

IN their incisive analysis of the Canadian health care system in this issue of the Journal,¹ Evans and his colleagues offer some illuminating observations on the position of the medical profession.

In Canada, where government pays almost all the bills, ...

Radon has recently become recognized as a potentially important cause of lung cancer in the general population. This chemically inert gas, which has been linked causally to lung cancer in miners of uranium and other underground minerals, occurs in nature ...

To the Editor: Recent interest in the causation of Parkinson's disease has raised the issue of whether the disease existed before the Industrial Revolution. An answer to this question can be found in Leonardo da Vinci's anatomical manuscripts in the ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Ng et al. interpret the data from their study¹ of alcohol consumption and withdrawal in patients admitted to the hospital for workup of a first seizure so as to discredit the commonly accepted concept of alcohol withdrawal seizures. Before ...

To the Editor: In an article in the Journal in 1986, Weil et al. described 16 patients who had cardiopulmonary arrest in the intensive care unit, 15 of whom had an endotracheal tube in place, were receiving mechanical ventilation before the arrest, and ...

To the Editor: The use of vest restraints in conjunction with wrist restraints is common in confused or combative patients and is not without risks. Death due to strangulation has been reported.^{1 2 3} We describe two patients who sustained brachial plexus ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Quality is hardly a new idea in medicine. Hippocrates' admonition to the physician, "First, do no harm," is an example of an outcome measure (treatment should not leave the patient worse off). A quality-assurance system could operationalize "harm" with ...

No extract is available for articles shorter than 400 words.

In May 1987, Alvin Tarlov, president of the Henry J. Kaiser Family Foundation, convened a group of scholars at a resort in Arizona to discuss the nature of the medical enterprise and the directions medicine must take in the future. One result was this ...

Yogi Berra would have described this informative book as "déjà vu all over again." Reading about the historical context of the Medicare program and the analysis of its successes and failures, while knowing that this account was written before the passage ...

No extract is available for articles shorter than 400 words.

Here is a revised and expanded edition of Gert's earlier book on moral rules (The Moral Rules. New York: Harper and Row, 1973). Three of the 14 chapters are new, and other chapters have undergone major revisions. Thomas Hobbes' influence becomes evident ...

Biomedical Science

Aging and the Skin. Edited by Arthur K. Balin and Albert M. Kligman. 372 pp., illustrated. New York, Raven Press, 1989. $75.

Allosteric Modulation of Amino Acid Receptors: Therapeutic implications. Vol. 1. (Fidia Research Foundation ...

HEALTHY WORK ENVIRONMENT

A workshop, entitled "Understanding Our Preferences: A Teambuilding Approach for a Healthy Work Environment," will be held in La Crosse, Wis., March 21 and 22. Deadline for enrollment is March 13.

Contact Extended Educ, 227 Main ...

No extract is available for articles shorter than 400 words.

These guidelines are in accordance with the "Uniform Requirements for Manuscripts Submitted to Biomedical Journals." (The complete document is available in the June 12, 1982, issue of the British Medical Journal and the June 1982 issue of the Annals of ...