WITH recent improvements in prophylaxis for graft-versus-host disease (GVHD), transplantation of bone marrow from an HLA-identical sibling has become a safer procedure than it was in the past decade and the treatment of choice for a variety of hematologic ...

CLOSTRIDIUM difficile has been associated with outbreaks of diarrhea and colitis in hospitalized adults receiving antimicrobial therapy.^{1 2 3 4 5} In addition, limited evidence of person-to-person transmission in the hospital^{6 7 8 9} has been gathered, and ...

IDIOPATHIC membranous nephropathy is the most common cause of the nephrotic syndrome in adults^{1 , 2}; it is responsible for approximately 8 percent of cases of end-stage renal disease due to primary glomerular disease.^{3 , 4} Prednisone therapy for patients ...

THE term "reactive arthritis" was first used by Ahvonen and coworkers in 1969¹ to describe joint disease developing after infection elsewhere in the body. Later, Dumonde² categorized such arthritides according to the nature of the association between the ...

MUSIC and medicine have always been closely linked. Apollo the Physician, referred to in early versions of the Hippocratic oath, was an accomplished musician. Shamans, who were perhaps the earliest health care providers, continue to use music and dance as ...

THE growing proportion of frail elderly persons in the population and the movement to deinstitutionalize chronically mentally ill patients from large state hospitals have produced important changes in the character of facilities providing long-term care. ...

THE past few years have seen extensive legal activity concerning the provision of immunity from liability, especially in antitrust suits, to physicians who take part in peer-review programs to monitor performance and to discipline fellow physicians in ...

Presentation of Case

A 56-year-old woman was admitted to the hospital because of abdominal pain, vomiting, and hematemesis.

She was well until the day of admission, when she experienced the acute onset of nonradiating midepigastric pain while she was ...

IS infection involved in the pathogenesis of chronic polyarthritis? Many teeth have been extracted, high colonic irrigations given, and prolonged courses of antibiotics administered in the belief that it is. The best supporting evidence in humans is the ...

Performing artists have always had medical problems, and these have been attended to by practitioners using a wide variety of diagnostic and therapeutic techniques. Interest in the illnesses of the more celebrated artists of the past continues to the ...

Idiopathic membranous nephropathy, one of the many renal diseases to emerge as a clearly defined clinicopathological entity after the use of renal biopsy became widespread, is characterized by distinctive changes in the glomerular capillary wall, which ...

Buck — Robert William Buck, M.D., of Waban, died on November 11 at the age of 95.

Dr. Buck received his degree from Harvard Medical School in 1921. He was a member of the American Medical Association. Dr. Buck held several offices with the Massachusetts ...

To the Editor: Human immunodeficiency virus (HIV) can be transmitted by the inoculation of blood by needles shared by drug abusers and by needle-stick injuries in health care workers, although the probability of infection in health care workers is low.^{1 ,...}

To the Editor: In the United States, female-to-male sexual transmission of HIV has been reported infrequently.* Until now, oral sex alone has not been proved to be a mode of transmission of HIV from women to men. We now report what appears to be a case ...

To the Editor: The silent period that follows exposure to HIV type 1 (HIV-1) and precedes seroconversion remains a problem in the screening of the blood supply.¹ Besides the virion structural proteins gag, pol, and env, the HIV-1 provirus also codes for ...

To the Editor: A high prevalence of antibodies to human T-lymphotropic virus Type I (HTLV-I) in persons with parasitologic evidence of Strongyloides stercoralis infection was recently reported from Okinawa by Nakada et al.¹ It has also been suggested ...

No extract is available for articles shorter than 400 words.

To the Editor: Nilsson et al. (April 14 issue)¹ described the induction of immune tolerance in patients with hemophilia and antibodies to factor VIII. As part of their regimen, patients with high-titer antibodies were initially treated with ...

To the Editor: Several patients with classic amyotrophic lateral sclerosis (ALS) were recently reported to have elevated antibody titers to Borrelia burgdorferi.¹ In one case, the disease apparently stabilized after antibiotic therapy. On the basis of ...

To the Editor: The increased survival of infants with extremely low birth weights has led to a resurgence of retinopathy of prematurity (ROP).¹ Young gestational age and low birth weight are among the most important risk factors for the development of ...

To the Editor: Batten disease, or neuronal ceroid lipofuscinosis (NCL), is a term applied to a group of inherited storage disorders whose cause is unknown, occurring mainly in infancy and childhood and characterized by the rapid accumulation of an ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

In our pragmatic world of superspecialization, we should welcome an honest effort to collect in an anthology more than 200 poems, by nearly 200 poets, dedicated to a lyrical insight into medicine. In the "old days," poetry was indeed part of the life of ...

Ian Kennedy is a professor of medical law and ethics at Kings College in London and a well-known author and broadcaster on topics in medical law. This book brings together 18 of his essays, many of them previously published, in the area of medical law and ...

Today, the expert generalist is rare indeed. The knowledge explosion, the devaluation of the theorist in both the biologic and the social sciences, and the rewards in income and status that go to the specialist, all help account for that fact. John Last ...

No one likes waste, be it ordinary household trash or medical waste, but radioactive waste arouses a special degree of public outcry, media attention, and political furor in this country. Accidents at the Three Mile Island and Chernobyl nuclear reactors ...

Workplace health promotion is a collection of efforts, based in the workplace, to improve the health of employees. Generally, these efforts focus on modifying employees' behavior, in such areas as smoking, diet, and exercise habits. Workplace health-...

No extract is available for articles shorter than 400 words.

UNIVERSITY OF CALIFORNIA, SAN DIEGO

The following programs will be held in San Diego, unless otherwise noted: "implementing Environmental Strategies for the Prevention of Alcohol-Related Problems" (Lake Arrowhead, Calif., Feb. 28–March 3); "Evaluating ...