IN Europe and North America relatively few women of childbearing age are infected with human immunodeficiency virus type 1 (HIV-1). As a result, perinatal transmission accounts for only a small proportion of the new cases of HIV-1 infection.^{1 , 2} By ...

MOTHER-to-child transmission is now virtually the only source of infection with human immunodeficiency virus type 1 (HIV-1) in infants, at least in countries where screening is carried out before blood transfusions.^{1 , 2} Little is known about the ...

STUDIES have shown that 30 to 50 percent of the infants born to women with human immunodeficiency virus (HIV) infection will acquire the virus from their mothers in utero, during labor and delivery, or post partum through breast-feeding.^{1 2 3 4 5 6} The ...

ALLOGENEIC bone marrow transplantation is a well-established treatment for a variety of conditions, particularly acute and chronic myeloid leukemia and acute lymphoid leukemia.¹ Usually, hematopoietic reconstitution occurs as a result of the sustained ...

CARBAMAZEPINE, first used clinically for the treatment of trigeminal neuralgia, was approved as an anticonvulsant in the United States in 1974. Despite the widespread use of this drug, not only for the treatment of virtually all types of epilepsy but also ...

MEASLES remains a major cause of morbidity and mortality in much of the world.¹ Most of the serious complications of measles are due to secondary bacterial and viral infections causing pneumonia and diarrhea^{2 , 3} or to postmeasles encephalomyelitis, an ...

RECOMMENDATIONS to limit the working hours of house officers^{1 , 2} have brought the issues of long work shifts, the level of resident supervision, and sleep deprivation to public consciousness. At the same time, medicine as a profession and internal ...

Presentation of Case

A 56-year-old man was admitted to the hospital because of hemoptysis.

He was well until about three weeks earlier, when there was the onset of weakness, malaise, anorexia, and chilliness. A physician made a diagnosis of a "viral ...

Although the total number of reported cases of the acquired immunodeficiency syndrome (AIDS) in children in the United States is less than 2 percent of the number in adults, the seriousness of the problem of pediatric AIDS threatens to grow in the coming ...

Learning clinical medicine is a lengthy process. From the first years of medical school through the residency years, students are gradually given more responsibility for patient care. The central rationale for this approach is that we learn clinical ...

The subject of industrial marketing and medical ethics has concerned thoughtful physicians and medical educators for several years. Medical-service companies that offer bonuses — cash or travel and lodging or both — for attendance at what are primarily ...

To the Editor: The article by Myers and Gleicher (Dec. 8 issue) ¹ is perhaps ill named. The word "successful" in its title suggests that it is admirable, even useful. The authors have produced little evidence in their study that the reduction in the ...

To the Editor: The National Institutes of Health (NIH) multicenter trial of high-frequency oscillatory ventilation (Jan. 12 issue) ¹ raises the difficult question of when to submit a new therapy to large-scale evaluation. If one waits too long, ...

To the Editor: Although Dr. Burrows and his colleagues (Feb. 2 issue) ¹ present an interesting analysis of the relation between asthma and serum IgE levels, we do not believe that their results are relevant to an understanding of intrinsic asthma. Their ...

To the Editor: Silverberg et al. (Feb. 2 issue) ¹ provide important information on abnormalities of parathyroid hormone (PTH) secretion and 1,25-dihydroxyvitamin D₃ (1,25(OH)₂D) formation in osteoporosis. Changes in the secretion of PTH were attributed ...

To the Editor: Pintor et al. (Feb. 9 issue) ¹ describe a child who presented with clinical and laboratory evidence of Laron dwarfism. The diagnostic factors in favor of this syndrome were high plasma levels of normal growth hormone, the lack of ...

To the Editor: In regard to Case 49–1988 (Dec. 8 issue),* I would like to raise several questions about the final pathological diagnosis of Histoplasma capsulatum. I am not convinced that this was the correct diagnosis.

Figure 4 was interpreted as ...

No extract is available for articles shorter than 400 words.

These two authors, lecturers in forensic psychiatry at the Institute of Psychiatry in London, have made a careful study (financed by the British government) of the way in which offenders are sent to the Criminal Lunatic Asylum at Broadmoor and how their ...

Delivering health care in a jail or prison requires that medical providers function outside "health care space." It requires subordinating the rhythms, assumptions, and control of medical practice to the demands of correctional systems. Medicine exists to ...

In The Health of the Republic, Beauchamp sets forth the notion of "republican equity" as the basis for providing medical care. He opposes the sale of commercial medical care in the market-place, which has led to the existence of millions of uninsured ...

This slim book by a psychiatrist at the University of Pittsburgh is the result of a year-long examination of the stresses faced by contemporary medical residents. Although the book was started before the public outcry over the tragic Libby Zion affair, ...

This video is a professionally executed documentary that provides a total perspective on the malpractice suit. Its purpose is to inform physicians about the litigation process, its emotional impact on the physician and his or her family, and the ...

Biomedical Science

Advances in Neuroimmunology. (Annals of the New York Academy of Sciences. Vol. 540.) Edited by Cedric S. Raine. 745 pp., illustrated. New York, New York Academy of Sciences, 1988. $185.

Affective Disorders. (Genetic Analysis of Complex ...

TWIN METHODOLOGY

The 2nd international course will be held in Leuven, Belgium, Sept. 4–8.

Contact Ctr. for Human Genetics, Univ. Hosp. Gasthuisberg, Herestraat 49, B-3000 Leuven, Belgium; or call (32) 16 215865.

INTERNATIONAL UPDATE IN DERMATOLOGY AND ...