CIGARETTE smoking is an important risk factor for coronary heart disease in women, as it is in men.^{1 2 3 4 5 6 7 8 9 10 11} The risk increases with the number of cigarettes smoked; it is elevated even in people who smoke only a few cigarettes a day,^{7 , 9} ...

CONGENITAL agranulocytosis, or Kostmann's syndrome, is a congenital disorder characterized by persistent severe absolute neutropenia (500 neutrophils per microliter or less). It is usually detected in the first months of life, with a bone marrow ...

MUCH of our knowledge about the epidemiology of infection with the human immunodeficiency virus (HIV) is based on surveillance of cases of the acquired immunodeficiency syndrome (AIDS) and on limited surveys of HIV seroprevalence and incidence in the ...

THE most severe complication of Plasmodium falciparum infection is cerebral malaria, from which more than 1 million children die annually in sub-Saharan Africa.^{1 , 2} Little is known about the pathogenesis of this condition.^{3 , 4} Recent reports suggest ...

DUCHENNE'S muscular dystrophy is an inexorably progressive disease that results in severe disability by the age of 10 to 12 years and in death in early adulthood. Despite recent major advances in the understanding of the molecular genetic defect,^{1 2 3 4 5} ...

THE cumulative number of reported cases of the acquired immunodeficiency syndrome (AIDS) now exceeds 90,000 and is projected by the Centers for Disease Control to reach 365,000 by the end of 1992.^{1 , 2} Furthermore, it is estimated that 1.0 to 1.5 million ...

THE two plasma forms of apolipoprotein B—B-100 and B-48 — are important proteins in mammalian lipoprotein metabolism.¹ Both are products of the same structural gene,² which in humans is located on chromosome 2.^{3 4 5} Apolipoprotein B-100 is a glycoprotein ...

Presentation of Case

A 77-year-old man was admitted to the hospital because of an inability to walk of acute onset.

The patient was in a stable state of health until three months earlier, when he began to experience difficulty in swallowing solids, with a ...

Between 1955 and 1987 the average tar and nicotine yield of American cigarettes declined substantially. The average tar yield (weighted for the volume of sales of the cigarette) fell from 34 to 13 mg, and the average nicotine yield declined from 2 to 0.9 ...

In the past five years, progress in understanding the molecular basis of Duchenne's muscular dystrophy has been substantial. The affected gene in this disease has been cloned, and its protein product, dystrophin, characterized.¹ The importance of ...

IN this issue of the Journal, Winkenwerder and his colleagues report on federal spending to date for research, education, and medical care to cope with the crisis caused by the human immunodeficiency virus (HIV). They also project probable federal ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: We have been following all known pregnant patients with human immunodeficiency virus (HIV) infection in Rhode Island, and have noted an interesting change in trend. In 1988, for the first time, a smaller number of children were born to HIV-...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

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To the Editor: In the movie A Fish Called Wanda, a caper comedy embodying various styles of British humor, Ken (played by Michael Palin) is a stutterer who does funny things. Never mind the fact that he stutters where true stutterers would not (Ken ...

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It is a promising moment when a person who has studied an organ over a lifetime, as Ronald Belsey has studied the esophagus, takes on an equally committed student, like David Skinner, to write a book on their subject. The result is a superbly written work ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Our understanding of the physiology of the breast and of the pathobiology of the most serious breast disease, cancer, has undergone considerable recent growth and change. A new book on breast diseases is therefore appropriate. To accomplish this, these ...

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Special Services

Biofeedback: Principles and practice for clinicians. Third edition. Edited by John V. Basmajian. 396 pp., illustrated. Baltimore, Williams and Wilkins, 1989. $49.95.

Essentials of Critical Care Medicine. By Martin J. Tobin. 578 pp., ...

CLINICAL MICROBIOLOGY AND IMMUNOLOGY

The 7th annual summer update will take place in Jackson, Wyo., July 16–22.

Contact Dr. John M. Matsen, Dept. of Pathology, Univ. of Utah School of Med., Salt Lake City, UT 84132; or call (801) 581–7480.

CONTROL OF ...