BICYCLING is an increasingly popular sport that is enjoyed by more than 85 million people in the United States. However, it has its hazards. In 1985, bicycling injuries accounted for an estimated 574,000 emergency room visits and 1300 deaths in the United ...

THE incidence of cutaneous malignant melanoma is rising more rapidly than that of any other cancer.¹ Although the upward trend appears to be due largely to intermittent exposure to solar ultraviolet radiation,² higher relative risks are associated with ...

HUMAN cryptosporidiosis was first described in 1976 in a three-year-old child with no obvious immunodeficiency.¹ It was subsequently recognized as a cause of severe diarrhea in patients with the acquired immunodeficiency syndrome and found to be a common ...

PRIMARY biliary cirrhosis is a well-characterized autoimmune disease of unknown cause that destroys the intrahepatic bile ducts of the liver. A characteristic serologic finding in patients with this disease is the presence of antimitochondrial antibodies ...

CYTOMEGALOVIRUS has been recognized since 1964 as a major pathogen in recipients of renal transplants.¹ In a prospective study of 272 renal-allo-graft recipients at the University of Minnesota, cytomegalovirus infection was a significant risk factor (P<...

PREVIOUS studies of the prognosis of patients infected with the human immunodeficiency virus (HIV) have focused mainly on the transition from HIV-positive status to AIDS (acquired immunodeficiency syndrome)-related complex,^{1 2 3 4} or from AIDS-related ...

THIS two-part article briefly presents the current understanding of both emergency management of actively bleeding esophageal varices and long-term care of varices that have bled and those that have never bled.

Esophageal varices result from portal ...

Presentation of Case

A newborn girl was admitted to the hospital because of respiratory distress, muscular hypotonia, and cutaneous vesicles.

The child was born at full term by a normal spontaneous vaginal delivery and was the second child of a 29-year-...

Medical education in this country has been shaped by many institutions and personalities, but a century ago none were more influential than the Johns Hopkins University and the men who conceived and directed its new hospital and medical school. The ...

Not many months ago, I gave my adult daughter a bicycle as a birthday present. After buying her a tire pump and a small tool kit, I wondered whether I should also buy her a helmet, the least expensive of which cost about $45. I complained about the price, ...

The question of the safety of drinking water has concerned the American public for more than 150 years. The issues have changed from the dramatic cholera and typhoid epidemics of the 1800s and early 1900s to other microbial pathogens and myriad chemical ...

Having a useful classification system is critical to understanding and treating any complex disease process. Some classification systems help with diagnosis, such as the Jones criteria for acute rheumatic fever. Some describe the natural history of a ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: One major side effect associated with the in vivo use of the murine monoclonal antibody OKT3 is the spontaneously reversible systemic clinical reaction that is invariably associated with the first one or two injections of the antibody.¹ ...

No extract is available for articles shorter than 400 words.

To the Editor: Human immunodeficiency virus type 2 (HIV-2) was first identified in 1985 in healthy West Africans,¹ and it was associated subsequently with the acquired immunodeficiency syndrome (AIDS) in West Africans and Europeans.^{2 , 3} One case of AIDS ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

William Osler was widely acknowledged to be the most influential physician in the English-speaking world at the turn of the century. Born in 1849 in Bond Head, Ontario, he was educated in Canada and Great Britain but emigrated to the United States in 1884 ...

The art and science of physical examination is the principal discipline that differentiates the physician from all other health professionals. An introduction to the physical examination moves the medical student into the role of doctor. With skill in ...

No extract is available for articles shorter than 400 words.

The field of medical genetics has undergone a dramatic revolution. The advent of molecular biology has not only revised the practice and potential of medical genetics, but has attracted a new generation of investigators schooled in recombinant technology ...

This is the fourth edition of an American classic. Since its first appearance in 1973, Sleisenger and Fordtran has been widely recognized as a comprehensive, authoritative work on gastrointestinal physiology and disease. The current edition lives up to ...

Parasitic Infections is the seventh volume of an excellent series on infectious diseases. The monograph is considerably less general than its title implies. Its principal emphasis is on protozoal infections, and the editors have selected only the most ...

Careful — this book is seductive. For those interested in the genre, almost any page will serve to start you browsing, reading, and musing, until suddenly the hour is late and your work neglected.

The first edition (1983) set a new standard for books ...

Medicine

Acute Myocardial Infarction: Emerging concepts of pathogenesis and treatment. Edited by Robert H. Cox. 203 pp., illustrated. New York, Praeger, 1989. $49.95.

Cancer and Aging. Edited by Terry V. Zenser and Rodney M. Coe. 251 pp. New York, ...

NEW TRENDS IN CARDIOVASCULAR THERAPY AND TECHNOLOGY

The 1st international workshop will be held in Genoa, Italy, June 14–17.

Contact Studio Viale von der Goltz, Via Goito, 26/7, 1–16122 Genoa, Italy; or call (39) 10 87–31–06.

FINGERS TO THE TOES

The 13th ...