SUDDEN death due to ventricular fibrillation may be the first manifestation of the Wolff–Parkinson–White syndrome.¹ Ventricular fibrillation results from atrial fibrillation with a very rapid ventricular response over an accessory atrioventricular ...

IN VITRO fertilization was developed as a treatment for infertility due to injury of the uterine tubes.^{1 , 2} The first pregnancy induced with this method resulted from the fertilization of a single oocyte aspirated during a spontaneous menstrual cycle.¹ ...

MORE than $2 billion is spent annually in the United States for the treatment of end-stage renal disease.¹ The costs associated with less severe renal disease are difficult to document, but may be substantial. Surprisingly, few epidemiologic studies have ...

VASOACTIVE intestinal polypeptide (VIP) is present in the normal human lung¹ and has been localized to nerve fibers supplying the smooth muscle, blood vessels, and submucosal glands in the trachea, bronchi, and bronchioles.^{2 , 3} These fibers probably ...

EIGHT years into the most serious pandemic of infectious disease in modern history, we possess the technology and resources to test for evidence of human immunodeficiency virus (HIV) infection accurately and economically. Yet there has been great ...

AMONG the hyperchylomicronemias, familial deficiencies of lipoprotein lipase (LPL) and of apolipoprotein C-II are rare variants in which the underlying biochemical defects are relatively well defined. The diseases are characterized by a deficiency of LPL, ...

Presentation of Case

A 41-year-old woman was admitted to the hospital because of mitral stenosis with slowly progressive exertional dyspnea and hoarseness.

There was a history of rheumatic fever at the age of 10 years, with persistent murmurs of mitral ...

Each day in the United States, television advertisements advocate the use of analgesics, available without prescription, for the aches, pains, and headaches of daily living. Because of the effectiveness of modern advertising, the sale of analgesics over ...

Much has been learned in recent years about the mediators of airway constriction in bronchial asthma and about the immunologic reactions that trigger the release of those mediators. Despite these undeniable advances, the pathogenesis of the disease ...

In this issue of the Journal, Kihara et al. report marked hypertriglyceridemia and pancreatitis in a young woman with autoimmune disease.¹ IgA antibodies to lipoprotein lipase appeared to block its function, resulting in marked hypertriglyceridemia. ...

The ethics of physicians' entrepreneurship have been debated extensively.¹ Proponents have pointed to the necessity of entrepreneurial arrangements; critics fear their effect on medical decision making, the quality of care, and the professionalism and ...

No extract is available for articles shorter than 400 words.

To the Editor: Dattwyler and his associates (Dec. 1 issue)¹ make important and provocative observations about a group of patients with a clinical diagnosis of chronic Lyme disease who have no apparent serologic response to the causative agent, Borrelia ...

To the Editor: To interpret human immunodeficiency virus (HIV) Western blots, the specific nature of each band must be understood. Bands near the top of each strip, for example, were thought to reflect the reactivity of antibodies with the HIV gpl60 ...

No extract is available for articles shorter than 400 words.

To the Editor: The risk of acquiring hepatitis A virus infection during travel to regions where it is endemic is well known. Less is known about the risk of acquiring hepatitis B virus infection during travel, and very little is known about the ...

No extract is available for articles shorter than 400 words.

To the Editor: The pathogenesis of IgA mesangial glomerulonephritis is controversial, but the presence of IgA directed toward food antigens,^{1 2 3 4} immune complexes containing IgA, and decreases in the levels of these immune complexes after the ...

No extract is available for articles shorter than 400 words.

To the Editor: Markedly elevated levels of the BB isoenzyme fraction of serum creatine kinase (CK-BB; EC 2.7.3.2) were found in three adult patients with osteopetrosis. Patient 1 was a 31-year-old black man who had no other medical problems. Patient 2 ...

To the Editor: Taylor et al. (Dec. 1 issue)¹ report a relation between the prevalence of cortical cataracts and exposure to ultraviolet B and no correlation between nuclear cataracts and ultraviolet exposure.

In the cataract-grading system described in ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Concern over the carcinogenic effects of manmade and naturally occurring toxins has dominated the field of environmental health for years. Only recently has major effort been given to studying noncancer end points such as teratogenicity, immunotoxicity, ...

Competition in the Health Care Sector has a style that exhibits either virtues or faults, depending on one's viewpoint. Of its eight sections, seven look back at papers from the 1977 Federal Trade Commission conference on competition in health care, ...

The contemporary tradition of physicians' memoirs seems to have begun 25 years ago with the publication of Intern (New York: Harper and Row, 1965) by "Dr. X" — a pseudonym later abandoned by author-physician Alan Nourse. Since then, a stream of nonfiction ...

Despite all that we have learned from medical science about disease and its therapy, mysteries of clinical practice remain. In Placebos and the Philosophy of Medicine (Chicago: University of Chicago Press, 1980), Howard Brody, a philosopher and family ...

No extract is available for articles shorter than 400 words.

HYPERTENSION IN BLACKS

The 4th international interdisciplinary conference will be held in Nairobi, Kenya, June 28–July 2.

Contact Intl. Soc. on Hypertension in Blacks, 69 Butler St., SE, Atlanta, GA 30303; or call (404) 589–3810.

SCIENTIFIC AND CLINICAL ...

The earthquake disaster of December 7, 1988, in Spitak, Armenia, set in motion a series of events that led to the delivery of 36,300 kg (80,000 lb) of dialysis equipment and supplies and two teams of dialysis workers from the United States to Yerevan, ...