LONG-TERM prognosis after myocardial infarction is related to the size of the infarct and to left ventricular function.¹ Thrombolysis with streptokinase is now established as effective therapy for improving survival^{2 , 3} and preserving left ventricular ...

RESULTS of a clinical trial (Protocol B-06) conducted by the National Surgical Adjuvant Breast and Bowel Project to evaluate segmental mastectomy (lumpectomy) in the treatment of Stages I and II breast cancers ≤4 cm in size were published in 1985.¹ Life-...

THE term "adoptive immunotherapy" is used to define the immune-mediated antileukemic effect of allogeneic bone marrow transplantation.^{1 , 2} Experimental studies in a variety of models involving transplantable tumors have demonstrated that cells in the ...

PROPHYLACTIC treatment with thyroid hormone is often recommended to reduce recurrences in patients after partial thyroidectomy for benign thyroid nodules. The rationale is the removal of a potential stimulus for recurrence by suppressing thyroid-...

ORAL anticoagulant agents (vitamin K antagonists, including warfarin and dicumarol) prevent thromboembolism by reducing the plasma concentrations of coagulation factors II, VII, IX, and X. Because patients with mechanical cardiac-valve prostheses are at ...

SOME of the practices that were controversial five years ago¹ in the care of the dying patient have become accepted and routine. Do-not-resuscitate (DNR) orders, nonexistent only a few years ago, are now commonplace. Many physicians and ethicists now ...

PRESSURE ulcers are a serious and all too common complication of immobility among the elderly. The prevalence of pressure ulcers is 3 to 11 percent in acute care hospitals and nursing homes.^{1 2 3} One study has suggested that the incidence over a three-...

Presentation of Case

A 76-year-old woman was admitted to the hospital because of pain about the right hip.

There was a history of the radiographic detection of osteosclerotic lesions of the lumbosacral spine, pelvis, right femur, and ribs; some of the ...

IN this issue of the Journal, White and his colleagues¹ report on a clinical trial in which 270 patients presenting with a first myocardial infarction were randomly assigned to receive intravenously either 1.5 million units of streptokinase or 100 mg of ...

For reasons that are unknown, chronic kidney failure of diverse causes tends to progress to end-stage renal disease. Several hypotheses have been advanced to explain the mechanisms by which renal insufficiency progresses,^{1 2 3} but none have been ...

No extract is available for articles shorter than 400 words.

To the Editor: The importance of atrial natriuretic factor (ANF) in volume and sodium homeostasis is well recognized.¹ Yet the part played by this hormone in the pathogenesis of primary hypertension is still subject to debate.² Ferrier et al. (Nov. 3 ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

It is remarkable that a disease we have known and studied for less than a decade is the subject of an entire book, let alone a book in its second edition. Yet, the explosion of data on the acquired immunodeficiency syndrome (AIDS) from a smorgasbord of ...

John Langone, a distinguished science writer and journalist, has written a very readable and remarkably comprehensive book about the manifold scientific, medical, and social aspects of infection with HIV. In a series of excellent chapters he discusses the ...

This is the book I have been waiting for. Edited by one of the dermatologists who was among the first to recognize the AIDS epidemic in 1981, it contains the best and most thorough collection of clinical photographs of the many cutaneous manifestions of ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Much has recently been written about the declining autopsy rates in U.S. hospitals: the rates have fallen from about 50 percent in the 1950s to less than 13 percent today (or less than 5 percent in many hospitals). These low rates persist despite some ...

NYU MEDICAL CENTER

A course, entitled "The Impact of Transplantation on Nursing Practice," will be offered in New York on May 12.

Contact NYU Medical Ctr. Post-Graduate Medical School, 550 1st Ave., New York, NY 10016; or call (212) 340–5295.

CALL FOR ...

As I have reported previously in the Journal,¹ there has been concern in Britain for several years about the state of the National Health Service (NHS). Long waiting lists for elective surgical procedures such as hip replacement and cataract operations, a ...