MOST of our knowledge of the clinical features and natural history of hypertrophic cardiomyopathy comes from observations derived from hospital-based study populations and investigations performed at referral institutions. Thus, the clinical picture of ...

HYPERTROPHIC cardiomyopathy is a disorder characterized by a nondilated, hypertrophied left ventricle in the absence of any overt cause.¹ Histologically, there is marked myocardial hypertrophy and fiber disarray.^{2 , 3} Functionally, the ventricle is ...

IN 1985, approximately 31 percent of American women in their late teens and early 20s reported that they had used marijuana within the past year.¹ The finding of such widespread use during the prime reproductive years raises important questions about the ...

THE use of silver nitrate for prophylaxis against gonococcal ophthalmia neonatorum was one of the triumphs of preventive medicine of the 19th century. Credé reported in 1881¹ that 2 percent silver nitrate reduced the incidence of gonococcal ophthalmia ...

THE attachment of bacteria to urothelial cells is an important factor in the pathogenesis of urinary tract infections.¹ The receptors for uropathogenic organisms, particularly Escherichia coli, are carbohydrate residues located on the surface glycolipids ...

THE latest published survey of contraceptive use in the United States was conducted in 1987. Of the 57.4 million women in the reproductive age group (15 to 44 years), 16.1 million (28 percent) were not exposed to unwanted pregnancy.¹ Of the remaining 41.3 ...

During the halcyon days of the populist political movements of the 1960s, much was said about the need for a broad-based program of publicly financed health care for all Americans. After the defeat of legislation to create such a system during the 1960s ...

Presentation of Case

A 24-year-old man was admitted to the hospital because of right flank pain and fever.

The patient was a native of Haiti, who came to this country five years before admission to attend educational institutions. There was a history of "...

Students of medical history observe a familiar sequence in the growth of knowledge about many diseases. The initial description is often a pathologic one, involving patients with the most advanced, usually fatal, form of the disease. Clinical–pathological ...

Gonococcal ophthalmia neonatorum is a potentially blinding disease. As noted elsewhere in this issue of the Journal, the introduction of silver nitrate eye drops for prophylaxis against gonococcal ophthalmia neonatorum was a major triumph of preventive ...

Urinary tract infections are a common cause of morbidity, especially among otherwise healthy women of childbearing age. Antibiotic therapy will cure the infection in approximately 80 percent of such women; additional episodes occur in the rest. Most ...

To the Editor: Preliminary reports suggest that zidovudine (AZT) has a positive risk-to-benefit ratio in some children with human immunodeficiency virus (HIV) infection. We believe, however, that Pizzo et al. (Oct. 6 issue)¹ did not provide data to ...

To the Editor: Infection with Chlamydia trachomatis has been reported in immunocompromised patients,^{1 , 2} but to our knowledge, not in association with HIV infection. We report a case of C. trachomatis pneumonia and possible pericarditis associated with ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: A severe febrile reaction occurred in a 38-year-old woman with multiple myeloma after transfusion of 60 ml of packed red cells. The transfusion was stopped immediately. Over the ensuing hour, profound septic shock developed that was ...

No extract is available for articles shorter than 400 words.

To the Editor: Shock-wave lithotripsy is being evaluated in clinical trials for the treatment of cholelithiasis.^{1 2 3 4 5} The first lithotriptor in clinical use (Dornier HM 3, Dornier, Munich, Federal Republic of Germany) required general anesthesia and ...

To the Editor: Computers used in diagnostic imaging, intensive care monitoring, and other such functions have been relatively immune to computer vandalism, because they have been special-purpose units that are not easily programmed by amateurs. A ...

No extract is available for articles shorter than 400 words.

This is an important contribution to the long-standing debate about how to deal with a major anomaly in American health care—the absence of provision for long-term disability — that has led to serious distortion in medical delivery and financing systems. ...

This book attempts to integrate knowledge about biologic aging with the clinical resources of the surgeon. There are 47 contributors, mostly from Canada or the United Kingdom, and all are recognized experts in the areas on which they have written.

The ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Despite major advances in diagnostic techniques ranging from immunohistochemistry to magnetic resonance imaging, the diagnosis of soft-tissue tumors continues to pose a challenge, particularly to the pathologist. Although the incidence of soft-tissue ...

No extract is available for articles shorter than 400 words.

AMERICAN SOCIETY OF INTERNAL MEDICINE

The "3rd Annual Leadership Development Conference: Tuning Up for the 1990s," will be held in Nashville, May 4–7.

Contact ASIM, Marketing Dept., 1101 Vermont Ave., NW, Suite 500, Washington, DC 20005; or call (202) 289–...