CHORIONIC villus sampling is a method of obtaining cells for the prenatal diagnosis of genetic abnormalities that can be used in the first trimester of pregnancy, thus providing a substantial advantage in terms of time over amniocentesis, which is usually ...

THE early treatment of acute myocardial infarction with intravenously administered thrombolytic agents represents an important advance in the management of this condition. Thrombolytic therapy has been demonstrated to recanalize occluded coronary arteries,...

APPROXIMATELY 50 to 60 percent of patients with breast cancer have disease that is apparently confined to the breast, without axillary nodal involvement.¹ The incidence of node-negative breast cancer will probably increase with the implementation of ...

SIXTEEN million persons in the United States have or have had cholesterol gallstones, most of which are radiolucent on abdominal plain films or oral cholecystograms.^{1 , 2} In vitro studies suggest that a large majority of such stones can be dissolved by ...

IN some disease states, one or more manifestations of hormonal excess may be caused by the interaction of one hormone with the receptor for a different hormone. When one receptor is activated by a signal designed for another, the event is termed a "...

IN 1978 we described a group of infants who presented with an apparently familial enteropathy characterized by protracted diarrhea from birth and hypoplastic villous atrophy.¹ Electron microscopical examination of surface enterocytes in a jejunal biopsy ...

Presentation of Case

A 60-year-old man was admitted to the hospital because of an intracardiac mass.

There was a questionable history of a coronary attack 15 years earlier, characterized by "crushing" chest pain, for which he was treated in another ...

During the past two decades, the diagnosis of genetic diseases in the fetus has become an integral part of obstetrical care. Most commonly, cells obtained by amniocentesis after a 16-week gestation are being used for testing. The safety, efficacy, and ...

The results of phase II of the National Institutes of Health–sponsored Thrombolysis in Myocardial Infarction trial (TIMI II), which appear in this issue of the Journal,¹ constitute a giant step forward in our understanding of the treatment of acute ...

During the past 18 years, three approaches have been introduced as alternatives to surgical treatment of gallbladder stones,^{1 2 3 4} a condition known since antiquity. All have as their objective the dissolution of the stones, leaving the gallbladder ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: When new, potentially lifesaving devices are introduced into clinical practice, the temptation to forgo randomized clinical trials is great. Unfortunately, proof of efficacy of management in a given clinical setting does not guarantee that ...

No extract is available for articles shorter than 400 words.

To the Editor: A 37-year-old woman was infertile, with irregular menses and a monophasic basal temperature. Conservative treatment with clomiphene was unsuccessful. Acromegaly was diagnosed at another institution in 1984. Her basal growth hormone level ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: We recently treated a 28-year-old victim of toothpick ingestion. We report the details of his case to reemphasize the need for adequate and immediate treatment in the event of such an ingestion.

The patient presented to the emergency room ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

This new and cohesive offering for beginning medical students has a number of important attributes — brevity, accuracy, readability, minimal use of jargon, and an absence of excessive enthusiasm for eponyms. Numerous textbooks of endocrinology are ...

Unifying themes in immunology are hard to come by. Historically, immunology has been described as a diverse set of medical and cellular phenomena, and it is only recently that basic principles of molecular genetics have established some common basis for ...

This book is described as a complete textbook of microbiology, intended for beginning students, medical technologists, and others who serve as experts and consultants in the field of medical microbiology. It is substantially updated and improved over the ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.