IN America, nearly 1 million institutionalized elderly persons have urinary incontinence, a condition associated with falls, fractures, pressure sores, urinary tract infections, urosepsis, and depression.^{1 , 2} The U.S. Surgeon General estimated that the ...

IDIOPATHIC membranous nephropathy is one of the most common glomerular diseases in adults and occurs worldwide. Its treatment is still controversial. Both retrospective and prospective controlled trials have produced conflicting conclusions about the ...

CHRONIC idiopathic hematuria, particularly when it is associated with substantial proteinuria, is usually of glomerular origin. Analysis of renal biopsy specimens from patients with this condition may identify glomerular abnormalities that are visible on ...

THE frequency of genetic mutations or chromosomal abnormalities in humans can be determined from the frequency of inherited disorders with characteristic physical abnormalities,^{1 2 3} the frequency of chromosomal abnormalities, such as translocations,⁴ and ...

DIVERSION colitis is an inflammatory process that occurs in segments of the colorectum after surgical diversion of the fecal stream. The condition is usually asymptomatic, but it may be manifested by drainage of bloody fluid and cramping pains.¹ Its ...

Why Universal Health Insurance?

The Paradox of Excess and Deprivation

The health care economy of the United States is a paradox of excess and deprivation. We spend about 11.5 percent of the gross national product (GNP) on health care, much more than any ...

CHRONIC idiopathic neutropenia is characterized by maturational arrest of neutrophil precursors in the bone marrow and a circulating neutrophil count of less than 1500 cells per microliter. Other hematopoietic cell counts are usually normal, and ...

Presentation of Case

A 50-year-old man with alcoholic cirrhosis of the liver was admitted to the hospital because of gastrointestinal hemorrhage.

There was a long history of alcohol abuse complicated by multiple minor injuries, withdrawal syndrome with ...

Two articles appear in this issue of the Journal that deal with apparently disparate topics. One, by Ponticelli and colleagues, describes the long-term outcome of an open, randomized, and prospective controlled trial of glucocorticoid combined with ...

Imagine two assembly lines, monitored by two foremen.

Foreman 1 walks the line, watching carefully. "I can see you all," he warns. "I have the means to measure your work, and I will do so. I will find those among you who are unprepared or unwilling to do ...

No extract is available for articles shorter than 400 words.

To the Editor: The study by Dyck et al. in the September 1 issue of the Journal ¹ permits none of the conclusions presented concerning the roles of sorbitol or myo-inositol in the pathogenesis of diabetic neuropathy. Dyck et al. found higher levels of ...

To the Editor: To determine what new trainees in nephrology are taught about treating potassium intoxication in renal failure, we conducted a survey by mail of the directors of nephrology training programs.¹ Each was asked to prescribe an initial ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Several recent articles have focused attention on recurrences of neurosyphilis after standard treatment of patients with concomitant infections with the human immunodeficiency virus (HIV).^{1 , 2} We report a case in which syphilitic uveitis ...

To the Editor: Nonophthalmic drops are ubiquitous in most surgical wards. Lack of familiarity with topical ophthalmic preparations on the part of patients, nonophthalmic medical staff, and nursing personnel contributes to the accidental instillation of ...

To the Editor: Advances, particularly in molecular biology, have provided valuable new insights into the pathogenesis of human neuropsychiatric diseases.^{1 2 3 4} Numerous sophisticated techniques, such as the identification of mRNA, were initially carried ...

To the Editor: Proximal sciatic-nerve lesions have been included in the differential diagnosis of low back pain since the 1920s.¹ We present a case of sciatic damage related to the use of an exercise bicycle — a device often used in the rehabilitation of ...

To the Editor: I drafted the following letter to the editor one week before I expected to hear the results of my amniocentesis:

"I am 40 years old and 19 weeks pregnant with what will presumably be my third child. I am on the basic-science faculty of a ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Here is an excellent primer for pediatricians that should be mandatory reading for all physicians who deliver primary care. The authors begin with an overview of normal psychosexual development, arguing that a child's capacity for sexual responsiveness ...

A medical student considering a career in psychiatry recently expressed to me his concern about some of the latest findings in molecular biology. He worried that the discovery that manic-depressive illness and Alzheimer's disease had strong genetic ...

This book is intended for serious beginners in child psychiatry, such as students and general practitioners. The authors attempt to present an updated view of the field as a growing body of knowledge, skills, and attitudes. They do not hesitate to show ...

STANFORD UNIVERSITY MEDICAL CENTER

The following programs will be held: "Dermatology: Update in Italy" (Abano Terme, Ischia, and Florence, Italy, March 19–26) and "Stanford Department of Dermatology Presents a Podiatric Medicine and Surgery Seminar in ...

These guidelines are in accordance with the "Uniform Requirements for Manuscripts Submitted to Biomedical Journals." (The complete document is available in the June 12, 1982, issue of the British Medical Journal and the June 1982 issue of the Annals of ...