WHETHER insulin-dependent diabetes mellitus increases a woman's risk of having a spontaneous abortion is controversial.¹ Although most earlier studies found no increased risk, several more recent studies have suggested that the risk of fetal loss in ...

DESPITE extensive investigation into immune reconstitution after bone marrow transplantation in humans, there is a paucity of information about the transfer of antigen-specific immunity from donors to recipients. Studies in animals have shown that the ...

APLASTIC anemia is a hematopoietic disorder characterized by bone marrow failure and pancytopenia. Several mechanisms have been implicated in the pathogenesis of this disease, including the loss of pluripotent stem cells, dysfunction of progenitor cells, ...

COMPETENT patients have the right to decide whether to accept or reject proposed medical care. Patients thought to be incompetent are denied this right, and others make their decisions for them. Competence is a legal concept; it can be formally determined ...

CIRRHOSIS of the liver, usually as a complication of alcoholism, is the third most frequent cause of death among those 25 to 64 years of age in urban areas such as New York City.¹ This alcohol-induced disease was formerly attributed exclusively to ...

CARDIAC involvement in multiple myeloma has been associated with certain complications of severe or prolonged disease.¹ Myocardial infiltration with amyloid has been well described as a cause of dilated or restrictive cardiomyopathy and congestive heart ...

Presentation of Case

A 92-year-old woman was admitted to the hospital because of diplopia and weakness of the right facial nerve and left leg.

There was a history of hypothyroidism, managed with levothyroxine. She was otherwise in good health until about ...

The care of women with diabetes who become pregnant represents one of the medical success stories of this century. Maternal mortality among diabetics fell sharply after the discovery of insulin in 1922. For decades, stillbirths and neonatal deaths ...

No extract is available for articles shorter than 400 words.

To the Editor: Alessandrini et al. (July 28 issue)¹ did not observe a significant difference in plasma levels of β-thromboglobulin (βTG) or platelet factor 4 (PF₄) in three small groups of patients with diabetes (6 with background retinopathy, 6 with ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: We present suggestive evidence of an adverse drug interaction between dextromethorphan and monoamine oxidase inhibitor therapy, which occurred in a 32-year-old woman with a history of chronic atypical depression.

After taking 30 mg of ...

To the Editor: A major factor in the cost of care for patients with the acquired immunodeficiency syndrome (AIDS) is short-term inpatient hospitalization.^{1 2 3 4} Previous studies have suggested that the primary reason that the care of patients with AIDS ...

To the Editor: After a three-month hospitalization at a community hospital, a patient was recently transferred to my care at a Veterans Administration Medical Center without copies of his medical records. Numerous studies had to be repeated, but more ...

No extract is available for articles shorter than 400 words.

The discovery of the structure of DNA by James Watson and Francis Crick in 1953 was the most important event in 20th-century biology. The hordes of molecular biologists unraveling the secrets of human physiology today are the intellectual heirs of a small ...

The relation between academia and industry has stimulated passionate debate over the protection of academic freedom and concern about how — or even whether — such a relation can be established to the benefit of both parties. In describing the history of ...

This examination of the adverse social and economic consequences of medical innovation is organized around four case studies: the use of diethylstilbestrol in medicine and animal husbandry, the development of the artificial heart (which has fortunately ...

No extract is available for articles shorter than 400 words.

Medical students find themselves facing a variety of decisions crucial to their later lives, decisions about which they feel anxious and uninformed. Unfortunately, there are no certain guidelines, and as the authors say, "Trying to predict the future of ...

This book contains the offerings at a conference on the history of internal medicine in the United States, held at the College of Physicians of Philadelphia. An overview by Paul Beeson and Russell Maulitz surveys the separation of American internists from ...

BAYLOR COLLEGE OF MEDICINE

The following courses will be offered in Houston: "Practical Aspects of Adolescent Medicine" (Feb. 11); "Occupational Medicine for the Practitioner: Medical Care and Legal Issues" (March 9–11); "The Cullen Course–1989: Clinical ...

WE have previously reported that adoptive immunotherapy using lymphokine-activated killer (LAK) cells plus interleukin-2 or high-dose interleukin-2 alone can result in the regression of cancer in a variety of murine models^{1 2 3 4} and in selected patients ...