A STRONG genetic component in the origin of non-insulin-dependent diabetes mellitus (NIDDM) is suggested by the concordance of 60 to 90 percent in monozygotic twins.^{1 2 3} The search for specific genetic markers for NIDDM, however, has yielded inconsistent ...

HYPERTENSION is an important risk factor for the development of coronary artery disease, and the development of angina pectoris in a patient with hypertension is therefore commonly ascribed to coronary atherosclerosis. However, angina may occur in a ...

MEDIUM-CHAIN acyl-CoA dehydrogenase (MCAD) deficiency is an inborn error of fatty acid metabolism that has recently drawn considerable attention because of its high incidence, unpredictable clinical presentation, and high mortality and because of the ...

CURRENT use of oral contraceptive agents increases the risk of myocardial infarction, especially among older women and cigarette smokers. Although this association is well established,^{1 2 3 4 5 6 7 8 9 10 11 12 13 14} whether there are excess risks ...

NICOTINE has been consumed in the form of tobacco and other plants for many hundreds of years. The compulsive use of tobacco has been observed in nearly every culture into which tobacco has been introduced. Nearly 30 percent of adult Americans smoke ...

CARNITINE (β-hydroxy-γ-trimethylaminobutyric acid) is an essential cofactor for the oxidation of fatty acids by mitochondria. It serves to carry long-chain fatty acids in the form of their acyl-carnitine esters across the barrier of the inner ...

Presentation of Case

A 59-year-old man was admitted to the hospital because of a right adrenal mass.

There was a long history of obesity, hypertension, and angina pectoris, with the more recent development of diabetes mellitus. A coronary-artery bypass ...

Inborn errors involving the oxidative metabolism of fatty acids represent a newly recognized area of human disease. Despite their recent discovery, these disorders in the aggregate appear to be relatively common. Their clinical presentation may be ...

Each year, diarrheal diseases kill at least 5 million children before they reach their fifth birthday. For the most part, poor countries bear the brunt of this burden. In many developing nations, it is usual for children to experience three or more ...

Over the past decade the issue of whether it is ever permissible to withhold life-sustaining treatment has been debated by doctors and ethicists and in the courts and state legislatures. Gradually, a consensus has emerged that it is indeed permissible and ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Central venous cannulation using either the subclavian or the internal jugular approach is a common procedure in critically ill patients. Performed correctly, the procedure is safe and the risk of complication low. Pneumothorax is the most ...

No extract is available for articles shorter than 400 words.

To the Editor: In their review of continuous ambulatory peritoneal dialysis, Nolph et al. (June 16 issue)¹ mention the use of measures of the quality of life in comparing different treatments for end-stage renal failure. However, drawing firm conclusions ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Some years ago I was discussing physician-writers with Anatole Broyard, a book reviewer for The New York Times. We eventually came around to Robert Coles. "Ah, Dr. Coles," Mr. Broyard fairly whistled into the telephone, "he can write about anything." As ...

In its own way, poetry is often as obscure and difficult as medicine. Why in the world would busy doctors spend time reading this short book of poems by a talented pediatrician? They would read it for pleasure and because every lesson in humanity offers a ...

This collection of related but independent essays explores an important theme in medical history: the iconography of illness. This historical view includes the popular beliefs about a particular disease, some of which were accepted as scientific fact for ...

Here is an entertaining and informative book. True, it is not particularly scholarly; no struggling through dusty diaries or musty museums to unearth new information here. It is remarkably personal, even autobiographical, for a book about people other ...

This is a study of the union of science and medicine in the setting of a modern medical school. Its subject is the medical school and hospital of Vanderbilt University, which were rebuilt in Nashville in the early 1920s as a model for medical education ...

No extract is available for articles shorter than 400 words.

Biomedical Science

Advances in Atrial Peptide Research. (American Society of Hypertension Symposium Series. Vol. 2.) Edited by Barry M. Brenner and John H. Laragh. 621 pp., illustrated. New York, Raven Press, 1988. $140.

The Alphabet and the Brain: The ...

WOMEN IN HEALTH SCIENCES

A workshop, entitled "The Role of Women in Health Sciences and Health Care in Developing Countries," will be held in Madras, India, Feb. 1–5.

Contact Prof. C.V. Ramakrishnan, Committee on Science and Technology in Developing ...