AN increasing number of patients with insulin-dependent diabetes mellitus (IDDM) are being treated with intensive insulin regimens designed to maintain normoglycemia. The principal complication of these regimens is hypoglycemia,^{1 2 3 4} which often occurs ...

A MAJOR effort in cancer research is directed at finding correlations between specific gene alterations and the clinical behavior of tumors. The outcome of such studies could provide new diagnostic tools and, eventually, new treatments. In breast cancer ...

STROKE following coronary-artery bypass surgery is often disabling. Early studies recognized that strokes were consistent, though uncommon, complications of revascularization. Loop et al.,¹ reported a stroke frequency of 2 percent among 6800 patients who ...

DIAGNOSTIC cardiac catheterization, including coronary arteriography, is performed more than 500,000 times a year in the United States.¹ Although it was formerly almost exclusively an inpatient procedure, technical improvements combined with an increased ...

APPROXIMATELY 20,000 persons are murdered in the United States each year, making homicide the 11th leading cause of death and the 6th leading cause of the loss of potential years of life before age 65.^{1 2 3} In the United States between 1960 and 1980, the ...

EVERY calling, every profession, every common activity of people develops its maxims, its short-hand messages, imparting to later generations the hard-earned lessons of the past. These maxims are often designed to save time that would be wasted, or to ...

PROTEIN C is the zymogen of a serine protease that regulates blood coagulation by inactivating thrombin-activated blood coagulation factors V and VIII.^{1 2 3} A congenital deficiency of this plasma protein is associated with a high incidence of ...

Presentation of Case

A 67-year-old woman was admitted to the hospital because of confusion and a left homonymous hemianopia.

There was a seven-year history of chronic lymphocytic leukemia. Twelve months before entry an x-ray film of the chest showed a ...

Research that analyzes prognostic variables in breast cancer can find clinically important associations although it cannot prove causal relations. Disease-associated variables that predict relapse and survival are particularly needed for neoplasms such as ...

AS a clinical cardiologist who began performing coronary angiography in 1965, I am startled to observe the changes in technique, procedures, and attitudes about coronary angiography that have taken place since its inception. For example, in the early ...

During 1984 and 1985, the last two years for which data are available, the number of people who died of injuries inflicted by firearms in the United States (62,897) exceeded the number of casualties during the entire 8 1/2-year Vietnam conflict.¹ In 1985 ...

To the Editor: Although the results of the study by Kershenobich et al. (June 30 issue)¹ raise hope that a treatment for cirrhosis is at hand, they are not conclusive because of serious flaws, most of which were identified in the accompanying editorial ...

To the Editor: The continued influx of immigrants from Southeast Asia will increase the likelihood that persons infected with schistosomiasis will be seen by American physicians. Drs. Kaplan and Tan Liu raised several points about the diagnosis of this ...

To the Editor: Hall et al. have recently reported on a trial of immunosuppressive drugs in renal transplantation that compares a short-term cyclosporine protocol (three months of cyclosporine followed by conversion to prednisolone and azathioprine) with ...

To the Editor: The symptoms of a patient with Parkinson's disease on a particular regimen of levodopa, alone or with a decarboxylase inhibitor, can vary markedly, adequate or inadequate control alternating with drug toxicity.¹ On the assumption that ...

To the Editor: Paroxysmal nocturnal hemoglobinuria (PNH) is a syndrome characterized by red cells with an increased sensitivity to lysis by complement. The total population of red cells in patients with PNH contains normal PNH-I and abnormal PNH-III ...

To the Editor: Prompt and effective antibiotic administration is an essential part of the management of febrile neutropenia. Aminoglycoside antibiotics are common first-line agents, but both efficacy and toxicity are closely related to serum ...

To the Editor: On July 8, 1988, we contacted the Illinois Department of Public Health to report five cases of cutaneous sporotrichosis. In an effort to establish the extent of the epidemic, these five patients were contacted, as were any patients who had ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

It is a measure of recent transformations in the field of human genetics that the first sentence of this book can state, "All branches of genetics owe their standing as a science primarily to the rediscovery — and full appreciation — in 1900 of ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

The eagerly awaited second edition of Rapaport's Introduction to Hematology has finally become available. The original work, published in 1971, was an extremely popular student manual. It was noted for a well-organized, clear, and consistent narrative ...

This book on mitral-valve prolapse is far more comprehensive than Jeresaty's monograph, which was published in 1979 (Mitral Valve Prolapse. New York: Raven Press). The multiple authorship of this book reflects the fact that mitral-valve prolapse has ...

The editors of this new textbook have undertaken "to provide a well-balanced, authoritative, and fully documented book that integrates scientific principles with the practice of respiratory medicine." This is a formidable task, and it is impressive that ...

UNIVERSITY OF CALIFORNIA, IRVINE

The following symposia will be held: "6th Annual Reider Laser Symposium–Gynecology" (Long Beach, Calif., Jan. 6 and 7); "6th Annual Reider Laser Symposium–Urology" (Long Beach, Calif., Jan. 6 and 7); and "American ...