THE Framingham study has demonstrated that the risk that coronary heart disease will develop increases with the level of obesity,¹ which is defined as the excessive accumulation of body fat. This association may be due in part to an adverse pattern of ...

THE incidence of systemic group B streptococcal infection during the first two months of life has not changed in 15 years.^{1 , 2} Invasive group B streptococcal infection develops in approximately 3 neonates per 1000 live births, resulting in approximately ...

PATIENTS who have undergone combined heart–lung transplantation have a marked improvement in their quality of life and exercise tolerance as compared with their pretransplantation condition.¹ However, no study has attempted to determine whether ...

THE mineralocorticoid hormone aldosterone is synthesized in the adrenal cortex under the primary control of the renin–angiotensin system. As with all adrenal steroids, the biosynthetic pathway to aldosterone (Fig. 1) starts with cleavage of the side chain ...

ALTHOUGH modern medicine provides great benefits to large numbers of people, medical professionals and clinical researchers have expressed concern about the effectiveness and appropriateness of many current and emerging medical practices. For example, the ...

INFANTS with severe combined immunodeficiency usually become ill in the first few months of life.¹ Although growth and development proceed normally for a few months, length and weight gain cease, and failure to thrive becomes a striking feature of the ...

Presentation of Case

A 25-year-old man was admitted to the hospital because of mediastinal, hilar, and subcarinal lymphadenopathy and a pericardial effusion.

He was well until six months earlier, when pain and stiffness developed in his neck and a ...

In this issue of the Journal, Wood and colleagues¹ at Stanford report on a clinical trial comparing two methods of weight loss: restricting energy intake and increasing energy expenditure. Each method was equally effective in reducing fat weight, raising ...

The concept of preventing neonatal infections by immunizing pregnant women has been appreciated for over a century and has been studied extensively in the prevention of tetanus, diphtheria, and pertussis infections.¹ Protective antibodies in the pregnant ...

Since the end of World War II the United States has seen two revolutions in its medical care system. It is now on the threshold of a third.

The first of these began in the late 1940s and early

1950s and continued through the 1960s. It can be described as ...

To the Editor: In his review (July 7 issue)* of inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, Dr. Grundy concluded that these drugs are effective and usually well-tolerated cholesterol-lowering agents. He also pointed out, ...

To the Editor: The pathogenesis of essential hypertension involves one or more hereditary disturbances. An impaired capacity of the kidneys to excrete sodium^{1 , 2} could result from a deficiency in, or a decreased renal response to, endogenous natriuretic ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Human infection by fish parasites belonging to the family Anisakidae was, until recently, a medical oddity in the United States. However, the number of cases of anisakiasis in the United States has increased markedly in recent years, and ...

This book draws a striking contrast between 19th-century medical attitudes toward female invalidism and the images of energetic, well-exercised women conveyed by the popular press. The author draws on three historical sources to trace the concept of women'...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

The title of this book refers to the federal government's entry into the arena of fiscal support for a system of hospice care for the terminally ill. The body of the book is a report on the National Hospice Study, commissioned by Congress in 1979. ...

No extract is available for articles shorter than 400 words.

AMERICAN MEDICAL ASSOCIATION

The 12th assembly of the AMA Hospital Medical Staff Section will meet in Dallas, Dec. 1–5.

Contact Dept. of Hosp. Medical Staff Services, AMA, 535 N. Dearborn St., Chicago, IL 60610; or call (312) 645–4754.

OSTEOPOROSIS

The ...

These guidelines are in accordance with the "Uniform Requirements for Manuscripts Submitted to Biomedical Journals." (The complete document is available in the June 12, 1982, issue of the British Medical Journal and the June 1982 issue of the Annals of ...