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October 27, 1988  Vol. 319 No. 17

Original Articles
1105-1111

THE findings of recent angiographic,1 2 3 angioscopic,4 pathological,5 , 6 and hematologic7 8 9 studies emphasize the role of plaque rupture, platelet activation, and thrombus formation in the pathophysiologic process of unstable angina. Unstable angina ...

1112-1117

    A NUMBER of studies1 2 3 4 5 6 7 have shown that school-children with a history of lower respiratory tract illnesses during infancy have both poorer lung function and a higher prevalence of bronchial hyperresponsiveness than subjects without such a ...

    1118-1123

    IN August 1983, the Centers for Disease Control (CDC), in cooperation with health care institutions throughout the United States, began an ongoing surveillance project to quantitate the risk to health care workers of acquiring infection with the human ...

    1123-1127

    SEVERAL studies in Africa have demonstrated the importance of human immunodeficiency virus (HIV) infection in selected African populations.1 2 3 4 5 A 1984 prevalence study in Kinshasa, Zaire, among employees at Mama Yemo Hospital, indicated that being ...

    Medical Progress
    1127-1134

    (Second of Two Parts)

    Cirrhosis

    The Underfilling versus the Overflow Hypothesis of Sodium and Water Retention

    The earlier, classic "underfilling" theory of sodium and water retention in cirrhosis proposed that ascites formation led to circulatory ...

    Medical Intelligence
    1135-1138

      FETAL hydrothorax has a perinatal mortality of 57 to 100 percent. Mortality is higher when the hydrothorax occurs in association with generalized hydrops than when it is an isolated finding.1 , 2 Intrathoracic compression of the developing lung produces ...

      Case Records of the Massachusetts General Hospital
      1139-1148

      Presentation of Case

      A 52-year-old man was admitted to the hospital because of severe diarrhea and weight loss.

      He was well until nine weeks earlier, when there was the abrupt onset of explosive, watery diarrhea one day after he ate raw clams and oysters ...

      Sounding Board
      1149-1151

      With health care expenditures in the United States running close to 12 percent of the gross national product, it is certainly not surprising that many are calling for strong cost-containment measures. One of the most frequently mentioned approaches is ...

      Correspondence
      1152-1154

      No extract is available for articles shorter than 400 words.

      1154-1155

      To the Editor: As a middle-aged general surgeon who has recently undergone coronary bypass graft surgery, I have looked for ways of preventing further atherosclerosis. I have assiduously avoided such known risk factors as obesity, smoking, and lack of ...

      1155

      No extract is available for articles shorter than 400 words.

      1155-1156

      No extract is available for articles shorter than 400 words.

      1156

      To the Editor: Nilsson et al. (April 14 issue)1 have reported the induction of immune tolerance in patients with antibodies to factor VIII (antihemophilic factor) by a combined regimen of intravenous IgG, cyclophosphamide, and factor VIII. The patients ...

      1157

      No extract is available for articles shorter than 400 words.

      1157-1158

      No extract is available for articles shorter than 400 words.

      1158

      To the Editor: The debate over the future form of health care financing and delivery is also important to us in South Africa, where we share many of the problems experienced in the United States (rising health care expenditures, incomplete coverage, and ...

      1158-1159

      To the Editor: In the good old days, patients usually had one doctor, who was likely to be a board-certified internist. He (rarely she) took care of the patient's various chronic problems, "kept up" in the medical specialties, tested himself with the ...

      1159

      To the Editor: Halloween seems to be giving way to more hazardous activities than trick-or-treating. Halloween egg throwing has become a popular prank among adolescents. Physicians may be unaware of the risk of injury that can result. We report five ...

      Occasional Notes
      1159-1161

      Dr. Adam Alpha, a young, able, and ambitious ophthalmologist, wished to "do better," and he hired a consultant. The consultant recommended a three=part strategy. Adam should advertise his "differentiating points" (unique services and skills), "systematize"...

      Book Reviews
      1161

      No extract is available for articles shorter than 400 words.

      1161-1162

      The preface states that the aim of this book is to "present auditory function and dysfunction from a biological perspective . . . providing data that will be of value to both teachers and pupils in audiology, otolaryngology, speech pathology and other ...

      1162

      In her preface, the author writes, "A single book describing the brain systems which govern the behavior of man, suggesting how these systems may malfunction to produce various types of mental disorder, and discussing how drugs might affect these systems ...

      1162-1163

      No extract is available for articles shorter than 400 words.

      1163

      Since the first edition of their manual on neurologic and neurosurgical intensive care was published in 1983, as the authors mention in their preface, the field has been consolidating. The art and science of intensive care in general have progressed, but ...

      1163

      No extract is available for articles shorter than 400 words.

      1163-1164

      No extract is available for articles shorter than 400 words.

      Books Received
      1164-1165

      Public Health and Environmental and Occupational Medicine

      Advances in Cancer Control: Cancer control research and the emergence of the oncology product line. (Progress in Clinical and Biological Research. Vol. 278.) Edited by Paul F. Engstrom, Paul N. ...

      Notices
      1165-1166

      UNIVERSITY OF CALIFORNIA, SAN DIEGO

      A workshop, entitled "Triple Threat: Alcohol, Other Drugs and Post Traumatic Stress Disorder," will be held in San Diego, Nov. 4–6.

      Contact UCSD Alcohol Program, UCSD Extension, X-001, La Jolla, CA 92093; or call (619) ...

      Corrections
      1166

      No extract is available for articles shorter than 400 words.

      1166

      No extract is available for articles shorter than 400 words.

      Health Policy Report
      1166-1172

      Japan's medical care system, remarkably inexpensive by American standards, has nevertheless entered an era of economic stress and incremental change as a consequence of efforts to address its most serious challenges. These challenges include medical ...

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