IT is no longer surprising that ionizing radiation can induce leukemia and other cancers in adults and children.^{1 , 2} However, data concerning the effects of radiation on the nervous system are limited. In 1974, we reported a significant increase in brain ...

HYPOGLYCEMIA is a well-recognized complication of severe Plasmodium falciparum malaria.^{1 2 3 4 5 6 7 8 9 10 11} A proportion of patients with severe infections become hypoglycemic before receiving any treatment^{3 , 10}; others become hypoglycemic during ...

THE results of three previous studies have been consistent with the hypothesis that increased body iron stores are associated with an increased risk of cancer^{1 , 2} and with increased overall death rates.³ Two lines of evidence provide a biologic rationale ...

IN recent years, the most common cause of infection in patients with neutropenia has shifted from gram-negative to gram-positive bacteria.^{1 2 3} An emerging controversy in the treatment of such patients is whether vancomycin should be included as a ...

THE future of biomedical research and technological innovation depends first and foremost on talent — on the quality of the biomedical man- and womanpower that is being developed now for tomorrow. The advice that the American educator and former president ...

(First of Two Parts)

Introduction

Volume-Control System

The regulation of the excretion of sodium and water in health and disease has been a topic of fascination for many investigators for several decades. It seems inescapable that there is some overall ...

Presentation of Case

A 67-year-old woman was admitted to the hospital because of dysphagia, epigastric pain, and a mass at the esophagogastric junction.

She was well until 8 to 10 months earlier, when she began to experience dysphagia for solid food but ...

A Sounding Board article and an exchange of letters in this week's Journal raise important issues about the ethics of medical research in other countries. In the former,¹ Dr. Barry discusses the special problems associated with clinical research on the ...

As pressure mounts within the scientific community to find a vaccine and develop strategies for the treatment of human immunodeficiency virus (HIV) infection, researchers are turning to developing countries, especially in sub-Saharan Africa, where large ...

Gainful employment has traditionally been one of medicine's goals.¹ Even the Hippocratic corpus includes suggestions about gaining the respect and attracting the business of patients.² Because of physicians' economic concerns, the history of medicine is ...

To the Editor: Readers of the Journal are told, in the May 12 issue,¹ about another "discovery" in nutrition. A similar earlier claim also misled the public and was exploited commercially.² It was easy to show that the claimed cholesterol-lowering effect ...

No extract is available for articles shorter than 400 words.

To the Editor: Opelz reported that matching of the HLA-A, -B, and -DR antigens of donors and recipients of cadaveric renal allografts had a beneficial effect on allograft survival in cyclosporine-treated recipients (May 19 issue),¹ in contradistinction ...

To the Editor: In his editorial on the possible causes of non-insulin-dependent diabetes mellitus (NIDDM), Cahill (May 12 issue)¹ draws attention to findings that appear to demonstrate either β-cell dysfunction or increased insulin resistance in this ...

To the Editor: Chorionic villi have become increasingly important in antenatal diagnosis. The tissue is used for the detection of chromosomal abnormalities and occasionally for the investigation of enzyme activities. Enzyme deficiencies can be determined ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Two nursing home patients had difficulty breathing due to occlusion of the mouth and nares by an involuntary snout-like reflex. In each case advanced dementia, edentia, and downward-angled nasal base were present. Intermittent life-...

No extract is available for articles shorter than 400 words.

This is the fourth edition of a book first published in 1974, testifying to the book's popularity with medical students. It follows very closely the educational objectives of the Association of Professors of Gynecology and Obstetrics, an organization ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

In spite of many years of debate about abortion, little insight has been gained. Now more than at any other time since 1973, the Supreme Court's decision in Roe v. Wade is in danger of reversal by a new Court, largely appointed by President Reagan. It is ...

No extract is available for articles shorter than 400 words.

Biomedical Science

Advances in Second Messenger and Phosphoprotein Research. Vol. 21. Edited by Robert S. Adelstein, Claude B. Klee, and Martin Rodbell. 222 pp., illustrated. New York, Raven Press, 1988. $80. (Series formerly entitled Advances in Cyclic ...

UNIVERSITY OF CHICAGO SCHOOL OF MEDICINE

The following courses will be offered in Chicago: "Clinical Neuroimmunology VI" (Nov. 3–5); "Antidote to Adjuvant: The Changing Role of Leucovorin in Clinical Oncology" (Nov. 9); "Lipoprotein (a): 25 Years of ...