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Table of contents for

July 7, 1988  Vol. 319 No. 1

Original Articles
1-7

NECROTIZING enterocolitis is a major cause of morbidity and mortality in preterm infants and those of low birth weight.1 2 3 4 A wide range of bacterial and viral pathogens have been isolated from the blood, stool, or peritoneal fluid of children with the ...

8-15

ENDOSCOPIO sclerotherapy of esophageal varices has been widely adopted as the primary treatment to prevent recurrent variceal bleeding. In contrast to the portacaval-shunt operation,1 2 3 4 it does not affect hepatic perfusion,5 is less invasive, and may ...

15-18

    DUCHENNE'S muscular dystrophy is a fatal X-linked recessive disease. Clinical descriptions of the disorder focus principally on skeletal-muscle degeneration, which causes a severe, debilitating weakness. Another manifestation, frequently overlooked, ...

    19-23

    THE molecular genetic basis of phenotypic diversity has been examined in the hemoglobinopathies and in inborn errors of metabolism involving enzyme deficiencies. A carefully studied example of the latter class of diseases is the most common form of ...

    Medical Intelligence
    24-33

    THE recent introduction of a unique class of cholesterol-lowering drugs offers new promise for the treatment of hypercholesterolemia. These drugs are inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, the rate-limiting enzyme in the ...

    33-37

    DEVELOPMENT of systemic infections with Neisseria meningitidis can usually be ascribed to the absence of protective IgM or IgG antibodies, or to the presence of IgA antibodies that block serum bactericidal reactions.1 , 2 Studies of rare complement-...

    Case Records of the Massachusetts General Hospital
    37-44

    Presentation of Case

    A 25-year-old man was admitted to the hospital because of hematemesis.

    He was well until one year earlier, when upper gastrointestinal tract bleeding developed, and the patient was informed of hepatic enlargement; no medical follow-up ...

    Editorial
    45

    No extract is available for articles shorter than 400 words.

    Sounding Board
    46-48

      Clinical cancer research is in jeopardy. Current budgetary constraints on federal support for biomedical research, the escalating costs of health care delivery, and the recent refusal of some third-party payers to support the costs of patient care as part ...

      Correspondence
      48-49

      No extract is available for articles shorter than 400 words.

      49-51

      No extract is available for articles shorter than 400 words.

      51-53

      No extract is available for articles shorter than 400 words.

      53

      To the Editor: The report by Williams et al. (Dec. 3 issue)* draws conclusions based on a prospective randomized trial comparing immediate brief-course chemotherapy with delayed chemotherapy in patients with pathological Stage II nonseminomatous germ-...

      53-54

      No extract is available for articles shorter than 400 words.

      54-55

      No extract is available for articles shorter than 400 words.

      55-56

      To the Editor: Eggers (Jan. 28 issue) 1 noted that 11 percent of black patients with end-stage renal disease received kidney transplants, as compared with 22 percent of white patients with the disease, during eight years of the end-stage renal disease ...

      56-57

      No extract is available for articles shorter than 400 words.

      57-58

      No extract is available for articles shorter than 400 words.

      Book Reviews
      58

      In an age when books frequently overlap, the first edition of Sir Roy Calne's textbook on liver transplantation was a unique, modern reference source when it was published in 1983. In this second edition, a number of new contributions reflect the rapidly ...

      58

      No extract is available for articles shorter than 400 words.

      58-59

      No extract is available for articles shorter than 400 words.

      59

      The field of noninvasive diagnosis of peripheral vascular disease continues to evolve and expand; these two books provide practical information on the techniques and clinical applications of noninvasive tests used in the diagnosis of cerebrovascular, ...

      59-60

      No extract is available for articles shorter than 400 words.

      60

      No extract is available for articles shorter than 400 words.

      60

      This book is dedicated to the memory of Gen Niwayama, a pathologist who was one of its two editors. The product of his and Resnick's labors is monumental in all respects, and serves as a fitting memorial to a man dedicated to the understanding of disease ...

      60-61

      No extract is available for articles shorter than 400 words.

      Books Received
      61-62

      Public Health and Environmental and Occupational Medicine

      Air Quality Guidelines for Europe. (WHO Regional Publications, European Series. No. 23.) 426 pp. Geneva, World Health Organization, 1987.

      Clinical Epidemiology: The essentials. Second edition. By ...

      Notices
      63

      PERIPHERAL VASCULAR DISEASE AND HYPERTENSION

      The seminar will be held in Hot Springs, Va., July 29–31.

      Contact Susan N. Seiders, Vascular Med. Assoc., Ltd., 650 N. 12th St., Lemoyne, PA 17043; or call (717) 761–8085.

      ANNALES DE MEDECINE INTERNE

      The ...

      Information for Authors
      64

      These guidelines are in accordance with the "Uniform Requirements for Manuscripts Submitted to Biomedical Journals." (The complete document is available in the June 12, 1982, issue of the British Medical Journal and the June 1982 issue of the Annals of ...