IT is estimated that 25 to 50 percent of people in most affluent societies are either obese or overweight.^{1 , 2} The development of these disorders must involve a prolonged period in which energy intake exceeds energy expenditure. However, the energy ...

OBESITY is a familial disorder that may be genetically determined.^{1 2 3} The familial occurrence of obesity could result from a similarity among siblings in either an excessive caloric intake, a deficit in energy expenditure, or both. Because of ...

THE voluntary deferral of blood donation by donors at risk for human immunodeficiency virus (HIV) infection and the laboratory screening since March 1985 of blood donations for HIV antibody have reduced the risk of transfusion-associated HIV infection.^{1 2} ...

EIGHTEEN years ago Melvin et al.¹ initiated a prospective study for the early detection of hereditary medullary thyroid carcinoma in a large family with multiple endocrine neoplasia type 2a. The family studied, the American branch of a large Swedish ...

ENDOMETRIOSIS affects as many as 1 in 15 women of reproductive age¹; the need for an effective nonsurgical therapy is pressing, particularly for patients concerned about their future fertility. Since endometriosis resolves after ovariectomy and menopause, ...

Cephalosporins

Cephalosporins have been grouped into "generations" on the basis of their spectrum of activity against gram-negative rods (Table 4). Since the pharmacologic characteristics of first- and second-generation cephalosporins have previously been ...

Presentation of Case

A 65-year-old woman was admitted to the hospital because of thrombocytopenia and uterine carcinoma with vaginal bleeding.

There was a five-year history of intermittent vaginal bleeding that was ascribed to uterine leiomyomas; a ...

There seems to be no end to the contradictory statements made about human obesity. Here are a few. Obesity is the result of a metabolic defect; no, it is no more than the unfettered drive for pleasure derived from eating. Obesity is genetically determined;...

When it appeared probable in late 1982 that the acquired immunodeficiency syndrome (AIDS) could be transmitted by transfusions of blood or blood components,¹ the Food and Drug Administration made a series of recommendations to reduce transmission by this ...

Endometriosis is the presence of tissue resembling endometrial glands and stroma outside the uterus. The anatomical sites most often affected by endometriosis are the ovaries, uterosacral ligaments, pelvic peritoneum, rectovaginal septum, cervix, vagina, ...

To the Editor: Both clinical investigators studying steroids and doctors working in intensive care units hoped that the two multi-center trials (Sept. 10 issue)^{1 , 2} would provide a conclusive answer in the controversy over high-dose glucocorticosteroid ...

To the Editor: Azidothymidine (AZT, or zidovudine [Retrovir]) has been shown to be capable of prolonging survival in patients with the acquired immunodeficiency syndrome (AIDS) who have had Pneumocystis carinii pneumonia and in patients with the AIDS-...

No extract is available for articles shorter than 400 words.

To the Editor: Hurley et al. (Aug. 27 issue)¹ showed that bone mineral density in the lumbar spine in patients with medullary carcinoma of the thyroid was significantly lower than that in normal controls. We have studied bone mineral density in the ...

To the Editor: An editorial by Haddy (March 5 issue)¹ stated that the role of endogenous digitalis-like factor in the pathogenesis of essential hypertension is still to be elucidated. I previously proposed that antidigoxin antibody may be therapeutic in ...

To the Editor: High-dose intravenous immunoglobulin has been shown to be effective in the treatment of several immune diseases, with no adverse effects.^{1 2 3} We have used this agent to improve the outcome of pregnancy in two women with severe Rh ...

To the Editor: The fairness of the present Medicare prospective payment system to hospitals, physicians, and patients should be reviewed by the Health Care Financing Administration. Jencks and Dobson (Sept. 10 issue)¹ state, "A hospital will be protected ...

To the Editor: Given the many changes that have occurred in the practice of medicine, I thought some revisions in the traditional Hippocratic oath were in order to allow physicians to comply with the regulations and potential conflicts of interest that ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Anesthesiologists and critical care physicians surely must be skilled in interpreting the electrocardiogram. Accurate diagnosis based on complete 12-lead recordings and assiduous monitoring of real-time ischemic and dysrhythmic events (as displayed on ...

No extract is available for articles shorter than 400 words.

This computer program contains 22 "classic" and 30 "difficult" case histories of patients with abdominal pain, presented in a problem-solving format. These cases represent a broad spectrum of abdominal disorders and show the variation of presentation ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Here is a topic seriously in need of new departures, a new textbook, and coverage of new treatment options and prevention. In the preface, the author states that the book is neither a compilation of research papers nor a textbook of microbiology. This is ...

No extract is available for articles shorter than 400 words.