GLUCOSE tolerance is defined as impaired if plasma glucose concentrations fall between glucose-tolerance values in normal subjects and those in patients with diabetes.^{1 , 2} Population studies in Pima Indians and other groups with a very high prevalence of ...

INSULIN is secreted in a pulsatile fashion in humans,¹ monkeys,² and dogs (both in vivo³ and from the isolated pancreas⁴). Pulsatile hormone secretion is found in several endocrine feedback loops⁵ in which oscillatory signals can enhance the sensitivity ...

THE contribution of abnormal insulin secretion, as compared with resistance to insulin action, to the pathogenesis of non-insulin-dependent diabetes has been controversial. We investigated whether noninsulin-dependent diabetes is associated with specific ...

ENTEROTOXIGENIC Escherichia coli is the organism most frequently associated with diarrhea in travelers to less-developed countries, accounting for 30 to 70 percent of cases.^{1 2 3 4} Several studies have shown that prophylaxis with agents active against ...

DIETARY saturated fatty acids have been implicated as an important factor in the production of high levels of plasma cholesterol in populations at high risk for coronary heart disease.¹ Although these fatty acids vary in chain length from 4 to 18 carbon ...

THE value of the autopsy in detecting diagnostic errors was emphasized by Cabot¹ in 1912 and has been confirmed by numerous subsequent studies.² Despite this overwhelming scientific evidence, autopsy rates in U.S. hospitals have fallen from about 50 ...

SUDDEN death is a well-recognized outcome of hypertrophic cardiomyopathy. It occurs at an annual rate of 3 percent, often in young patients,^{1 2 3 4} in whom the most likely precipitating mechanism is an arrhythmia.¹ Ventricular tachycardia or fibrillation, ...

Presentation of Case

A 33-year-old man was admitted to the hospital because of cough, fever, and a left pleural effusion.

He was well until about five weeks earlier, when a Dry cough, headaches, myalgia, malaise, and anorexia appeared. He stayed off his ...

Non-insulin-dependent diabetes (Type II, or maturity-onset diabetes) remains a popular topic in biomedical science because of its prevalence, morbidity, and undefined pathophysiologic aspects. Several general facts about the disorder have been known for ...

THE report by Bonanome and Grundy in this issue of the Journal ¹ demonstrates convincingly that a diet high in stearic acid (18 carbon atoms and no double bonds — 18:0) does not cause an elevation in plasma levels of low-density lipoprotein (LDL) ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: In a paper that purports to study drunk drivers, scientific accuracy demands that the study's authors clearly define the method by which presenting patients are identified as "drivers." There is a social stigma associated with being a ...

No extract is available for articles shorter than 400 words.

Do the conditioning and training of professional athletes determine their length of life or cause of death? We have addressed this question through an analysis of the rate and causes of death of American professional baseball players.

The cohort comprised ...

Two types of smokeless tobacco are popular among baseball players today: moist snuff, commonly referred to as "dip," and chewing tobacco. Snuff is a finely ground, processed tobacco product that is placed between the cheek and gum. Chewing tobacco is cut ...

One of the most distinctive features of American culture is its commitment to the concept of progress. The goal of progress has long dominated the rhetoric of government, business, science, and politics.

There are few areas of intellectual or social ...

At one time or another, nearly every student of medicine has been dismayed by the vast number of eponyms attached to diseases, syndromes, anatomical parts, surgical instruments, and virtually everything else in medicine. Whether we like it or not, eponyms ...

The concept of the self is one that has attracted the interest of theologists, philosophers, and in more recent times, psychoanalysts. That Dr. Mendelsohn, an analyst of adults and children, has devoted four volumes to this topic is a tribute to both its ...

Here, the author mixes Eastern meditation with Western neurophysiology and creates a scientific basis for the "relaxation response." Then he mixes faith, religion, literature, poetry, and medicine with positive thinking, and comes up with the "principle ...

No extract is available for articles shorter than 400 words.

Here is a compassionate, readable perspective for the "helping professional." Parkes' work examines several aspects of grief in adult life with special consideration given to the reactions of the survivor. In its successive chapters, the focus is on the ...

ARTOIS-BAILLET LATOUR HEALTH PRIZE

The prize for 1989 will reward an important contribution to the knowledge of the role of viruses and oncogenes in cellular pathology. Deadline for submission is July 1, 1988.

Contact Denis Dewez, Embassy of Belgium, 3330 ...