IN 1881 Credé introduced silver nitrate prophylaxis for the prevention of gonococcal ophthalmia neonatorum.¹ The simple method was immediately hailed as one of the triumphs of preventive medicine, because gonococcal ophthalmia virtually disappeared on ...

PRIMARY hyperparathyroidism is a common disorder characterized by hypercalcemia due to excessive secretion of parathyroid hormone. The causes of the underlying conditions are unknown. In most cases, a single hypercellular parathyroid gland (adenoma) is ...

THERE is a large body of evidence that Type I insulin-dependent diabetes mellitus (IDDM) is of autoimmune origin.¹ Consequently, recent therapeutic efforts have been directed toward intervention with various immunosuppressive agents. The results of ...

MAJOR malformations are said to be two to three times more common in infants whose mothers had insulin-dependent diabetes mellitus at conception.¹ The recognition that these diabetes-associated malformations occur in the first six weeks after conception² ...

THERE has been a good deal of controversy about the current federal regulations governing the treatment of severely handicapped infants — the "Baby Doe" regulations¹ — based on the 1984 amendments to the Child Abuse Prevention and Treatment Act.² An ...

THE neurofibromatoses consist of two distinct disorders,^{1 , 2} the genes for which have recently been located on separate chromosomes.^{3 4 5 6} Neurofibromatosis 1, also called von Recklinghausen's neurofibromatosis, affects approximately 100,000 people in ...

CLINICALLY evident generalized graft-versus-host disease is not thought to occur as a consequence of transplantation of most solid organs. The requisite large inoculum of donor lymphoid cells and inability of the recipient to destroy these passenger cells^...

Presentation of Case

A 44-year-old woman was seen at this hospital because of thrombocytosis.

She was well until six months earlier, when anorexia developed and she lost 4.5 kg in weight.

Two months before entry evaluation elsewhere showed that the ...

Primary hyperparathyroidism is a common disorder, and its causes are uncertain. Most patients have overactivity of a single gland, in the form of an adenoma. It has been suggested that parathyroid adenoma may be an expression of parathyroid hyperplasia, ...

After repeated demonstrations of the pathogenic role of autoimmunity in insulin-dependent diabetes mellitus (IDDM), physicians have turned their attention to treating this disease with immunosuppressive drugs. Recently, interest has centered on the use of ...

Before total parenteral nutrition was possible, most infants with extensive intestinal loss died of starvation and infection. The ability to provide sufficient calories intravenously has permitted the survival of many infants with short intestines. For ...

No extract is available for articles shorter than 400 words.

To the Editor: The earliest trial of zidovudine (Retrovir; formerly called azidothymidine, or AZT) in the treatment of human infections with human immunodeficiency virus began in 1985. Nearly 9000 persons with acquired immunodeficiency syndrome (AIDS) or ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: The drug of choice in the treatment of persistent hiccup is chlorpromazine, a dopaminergic blocker.^{1 , 2} Haloperidol is the drug of second choice and also has well-established dopaminergic-antagonistic effects.³ The drug of third choice is ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

As the field of computer education in clinical medicine develops, computer algorithms have been created to provide challenges to a wide audience. That is the case with this program. Stupor and Coma, from the computer sciences department of Massachusetts ...

It is always difficult to develop a clinical discussion of viral encephalitis. For most physicians, the factors that lead to the diagnosis are deceptively simple. They include the onset of an acute or subacute encephalopathy with or without fever, the ...

The first book here was written for patients and families affected by multiple sclerosis. As such, it meets a deeply felt need, and it meets it well.

After an introductory overview, there are chapters discussing symptoms and signs, how a diagnosis is made,...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Ocular injuries are an important cause of blindness. Prompt, complete, and accurate diagnosis followed by effective treatment can often avert or minimize visual loss. Ocular injuries also constitute an important source of litigation.

This book provides a ...

Biomedical Science

Advances in Age Pigments Research. (Advances in the Biosciences. Vol. 64.) Edited by E. Aloj Totaro, P. Glees, and F. Pisanti. 427 pp., illustrated. New York, Pergamon Press, 1987. $94.

Antibiosis and Host Immunity. Edited by Andor ...

ASSOCIATES OF CLINICAL PHARMACOLOGY

The 12th Annual Meeting will be held in Seattle, April 19–23.

Contact ACP, 2317 International Ln., Suite 115, Madison, WI 53704: or call (608) 244–2973.

CRITICAL CARE MEDICINE 1988

The 2nd Annual Review and Update ...