CURRENT projections indicate that by 1991 at least 100,000 cases of Pneumocystis carinii pneumonia will have occurred in patients with the acquired immunodeficiency syndrome (AIDS) in the United States.¹ The rapidly growing incidence of this infection has ...

ALTHOUGH the plasma anion gap is widely used in the evaluation and classification of acid–base disorders,^{1 2 3 4} the value of the urinary anion gap (sodium plus potassium minus chloride) in the evaluation of metabolic acidosis is not well recognized. ...

JUVENILE acquired hypothyroidism has an insidious onset characterized by gradual slowing and eventual cessation of growth, thickening and yellowing of the skin, and coarsening of the facial features.^{1 , 2} Untreated patients eventually have delayed ...

SEVERAL groups of investigators have independently developed evidence that inflammation plays an important part in the airway hyperresponsiveness characteristic of bronchial asthma.^{1 2 3 4 5 6 7} Corticosteroids act directly to suppress this inflammatory ...

DURING cardiopulmonary resuscitation (CPR), precordial compression generates systemic blood pressure and blood flow.^{1 2 3} The cardiac output during experimental precordial compression is maintained at levels corresponding to approximately 25 percent of ...

THE doctor caring for a patient with lung cancer faces difficult choices, since the treatment of this condition is often futile. Surgery offers the only real chance of cure, but it is suitable only for the small proportion of patients with limited disease ...

THE past decade has witnessed great changes in our understanding of the molecular origins of cancer. Much of this progress stems from the discovery of specific genes, the oncogenes, which are carried in the genomes of a variety of tumor cells and appear ...

Presentation of Case

A 73-year-old man was admitted to the hospital because of right hemiparesis.

He was well until 15 months earlier, when he awoke from a nap with nausea and a severe supraorbital headache that was more marked on the left side; he ...

Growth is a complex process. It depends on an adequate nutritional substrate, stimulation by a variety of hormones, including growth hormone, thyroid hormones, and gonadal steroids, and mediation by growth factors such as the somatomedins, epidermal ...

Asthma is a disease characterized by an increase in airway reactivity together with a propensity for the airways to constrict in response to a variety of stimuli.¹ The cumulative prevalence of this disorder in America is estimated to be between 5 and 7 ...

Multiple factors contribute to the process of deciding on a choice of treatment for the patient with cancer. Some of these factors, such as the histologic diagnosis, stage of disease, functional status, and pattern of metastatic spread, are attributes of ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: The effort by Olson et al. (Sept. 17 issue)¹ to characterize deposits of cardiac amyloid is identical to our work on the characterization of amyloid deposits in muscle and nerve biopsy specimens from patients with amyloid polyneuropathy of ...

No extract is available for articles shorter than 400 words.

To the Editor: We have treated a 45-year-old woman with metastatic melanoma with high-dose interleukin-2 alone, administered intravenously as a continuous infusion. On the first two days the patient received 3 x 10⁶ U per square meter of body-surface ...

No extract is available for articles shorter than 400 words.

To the Editor: We have previously demonstrated that a physiologic increase in dietary calcium intake can suppress the parathyroid hormone–1,25-dihydroxyvitamin D axis in patients with primary hyperparathyroidism.* We reasoned that the converse may also ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Emergency medicine has established itself as a viable specialty, not only because of the vigorous efforts of those who practice it but also because it truly constitutes another territory with its own challenges. To help us find our way, there is a new ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Ever since Hargraves described the lupus erythematosus cell phenomenon in the 1940s and Friou introduced the antinuclear antibody test in the 1950s, rheumatology has laid claim to a motley collection of clinical syndromes held together by the twin threads ...

This is an ambitious attempt to integrate diagnostic microbiology within a pathogenic, clinical, and epidemiologic context. It is an enormous undertaking by a group of coauthors who are mainly from the field of clinical microbiology. It is intended as a ...

When a favorite textbook appears in a second edition, it is difficult to be critical. The reader hopes to find preserved everything that made the book useful in the past and expects that it will incorporate the important conceptual changes and technical ...

Biomedical Science

Neuropeptides and Brain Function. (Progress in Brain Research. Vol. 72.) Edited by E.R. de Kloet, V.M. Wiegant, and D. de Wied. New York, Elsevier, 1987. $141.50.

Perspectives in Biological Dynamics and Theoretical Medicine. (Annals of ...

NEUROFIBROMATOSIS AWARDS

The Neurofibromatosis Institute is accepting applications for the George Krejci Memorial Award.

Contact Dr. Vincent M. Riccardi, Neurofibromatosis Inst., 715 Bison Dr., Houston, TX 77079; or call (713) 558–9907.

PREVENTION AND ...